Detailed information for compound 548444

Basic information

Technical information
  • TDR Targets ID: 548444
  • Name: ethyl pyridine-4-carboxylate
  • MW: 151.163 | Formula: C8H9NO2
  • H donors: 0 H acceptors: 2 LogP: 1.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1ccncc1
  • InChi: 1S/C8H9NO2/c1-2-11-8(10)7-3-5-9-6-4-7/h3-6H,2H2,1H3
  • InChiKey: MCRPKBUFXAKDKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-pyridinecarboxylic acid ethyl ester
  • isonicotin ethyl ester
  • ethyl isonicotinate
  • Isonicotinic acid ethyl ester
  • 1570-45-2
  • ZINC00388053
  • 5-22-02-00190 (Beilstein Handbook Reference)
  • AI3-22194
  • BRN 0122942
  • EINECS 216-379-2
  • NSC 6854
  • gamma-Pyridinecarboxylic acid ethyl ester
  • .gamma.-Pyridinecarboxylic acid ethyl ester
  • 4-Carbethoxypyridine
  • 4-Carboethoxypyridine
  • 4-Pyridinecarboxylic acid, ethyl ester
  • Ethyl 4-pyridinecarboxylate
  • Isonicotinic acid, ethyl ester
  • NSC6854
  • WLN: T6NJ DVO2
  • AIDS-167047
  • T5225219
  • AIDS167047
  • 104736_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cpg binding protein 0.003 0.0162 0.0578
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0052 0.0187
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0052 0.0187
Loa Loa (eye worm) RNA binding protein 0.0063 0.0397 0.0385
Brugia malayi nuclear receptor NHR-67 0.0014 0.0052 0.0041
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0397 0.0385
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.0009 0.0014 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0167 0.0595
Entamoeba histolytica hypothetical protein 0.0009 0.0014 0.5
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0052 0.0041
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0167 0.0155
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Brugia malayi CXXC zinc finger family protein 0.0028 0.015 0.0139
Schistosoma mansoni thyrotroph embryonic factor related 0.0009 0.0014 0.005
Schistosoma mansoni intermediate filament proteins 0.0026 0.0138 0.0493
Brugia malayi Cell death specification protein 2 0.0009 0.0014 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2801 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0298 0.0286
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0167 0.0595
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0065 0.0053
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0188 0.0177
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0592 0.2113
Brugia malayi nuclear receptor NHR-88 0.0014 0.0052 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0167 0.0155
Schistosoma mansoni cpg binding protein 0.003 0.0162 0.0578
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0014 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0015 0.006 0.0049
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0052 0.004
Brugia malayi nuclear receptor RXR 0.0016 0.0065 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0592 0.2113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0167 0.0155
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.006 0.0215
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0009 0.0014 0.005
Echinococcus multilocularis protocadherin 11 0.0009 0.0014 0.005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0397 0.1418
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0167 0.0595
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.006 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0167 0.0156
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0167 0.0156
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0052 0.0187
Loa Loa (eye worm) hypothetical protein 0.0026 0.0138 0.0126
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0051 0.0039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0014 0.005
Echinococcus granulosus protocadherin 11 0.0009 0.0014 0.005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0012 0.0044
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0052 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0052 0.0187
Brugia malayi hypothetical protein 0.0009 0.0014 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0592 0.2113
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0048
Echinococcus granulosus lamin 0.0026 0.0138 0.0493
Brugia malayi Cell death specification protein 2 0.0009 0.0014 0.0002
Echinococcus granulosus X box binding protein 1 0.0282 0.1959 0.6991
Loa Loa (eye worm) cell death specification protein 2 0.0009 0.0014 0.0002
Onchocerca volvulus 0.003 0.0167 1
Brugia malayi conserved hypotetical protein 0.0014 0.0052 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Schistosoma mansoni hypothetical protein 0.0282 0.1959 0.6991
Loa Loa (eye worm) hypothetical protein 0.1409 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Echinococcus granulosus dnaJ subfamily B 0.04 0.2801 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0014 0.005
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1409 1 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0397 0.1418
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0397 0.0385
Loa Loa (eye worm) hypothetical protein 0.0033 0.0188 0.0176
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0397 0.1418
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0025
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0167 0.0595
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0375 0.1338
Schistosoma mansoni hypothetical protein 0.04 0.2801 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0052
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0167 0.0595
Brugia malayi Hepatic leukemia factor 0.0009 0.0014 0.0002
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0052 0.0187
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0065 0.0231
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0051 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0167 0.0156
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.0009 0.0014 0.005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0167 0.0156
Onchocerca volvulus 0.0026 0.0138 0.8135
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0052 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0167 0.0156
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0167 0.0156
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0167 0.0595
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0052 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0167 0.0156
Echinococcus granulosus tar DNA binding protein 0.0063 0.0397 0.1418
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0065 0.0053
Brugia malayi ecdysteroid receptor 0.003 0.0167 0.0156
Schistosoma mansoni cpg binding protein 0.0028 0.015 0.0537
Schistosoma mansoni nuclear receptor 0.0014 0.0052 0.0187
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0167 0.0156
Echinococcus granulosus cpg binding protein 0.003 0.0162 0.0578
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0167 0.0156
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0052
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.0009 0.0014 0.005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0298 0.0287
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0167 0.0595
Schistosoma mansoni thyroid hormone receptor 0.003 0.0167 0.0595
Brugia malayi Cell death specification protein 2 0.0009 0.0014 0.0002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0014 0.005
Brugia malayi RNA binding protein 0.0063 0.0397 0.0386
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0012 0.0044
Brugia malayi intermediate filament protein 0.0026 0.0138 0.0127
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Schistosoma mansoni thyroid hormone receptor 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0052 0.0187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0592 0.2113
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0052 0.0187
Brugia malayi hypothetical protein 0.0014 0.0052 0.0041
Echinococcus multilocularis X box binding protein 1 0.0282 0.1959 0.6991
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0052 0.0187
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0592 0.0581
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0138 0.0127
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0052
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Schistosoma mansoni lamin 0.0026 0.0138 0.0493
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0052 0.0187
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0026 0.0135 0.0123
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.033 0.5
Brugia malayi nuclear receptor NHR-88 0.003 0.0167 0.0156
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0167 0.0595
Brugia malayi nuclear hormone receptor 0.0014 0.0052 0.0041
Schistosoma mansoni hypothetical protein 0.0033 0.0188 0.067
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0167 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0167 0.0595
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0167 0.0156
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0041 0.0146
Onchocerca volvulus 0.0028 0.015 0.8934
Schistosoma mansoni zinc finger protein 0.0014 0.0052 0.0187
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Echinococcus granulosus intermediate filament protein 0.0026 0.0138 0.0493
Schistosoma mansoni par domain protein 0.0009 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0167 0.0595
Brugia malayi hypothetical protein 0.0009 0.0014 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.015 0.0138
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.0215
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0052 0.0187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0167 0.0155
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Echinococcus multilocularis lamin 0.0026 0.0138 0.0493
Echinococcus granulosus lamin dm0 0.0026 0.0138 0.0493
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0052 0.004
Echinococcus granulosus ccaat enhancer binding protein delta 0.0009 0.0014 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0592 0.2113
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.006 0.0215
Loa Loa (eye worm) hypothetical protein 0.1409 1 1
Brugia malayi TAR-binding protein 0.0063 0.0397 0.0386
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0592 0.058
Schistosoma mansoni lamin 0.0026 0.0138 0.0493
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0052 0.0187
Brugia malayi hypothetical protein 0.0009 0.0014 0.0002
Echinococcus multilocularis geminin 0.0176 0.1203 0.4296
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0167 0.0595
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0138 0.0126
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0592 0.2113
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0052 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Brugia malayi ecdysone receptor 0.0014 0.0052 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0167 0.0595
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0167 0.0595
Echinococcus multilocularis GPCR, family 2 0.0015 0.006 0.0215
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.0215
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0052 0.0041
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0397 0.1418
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0052 0.0041
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0167 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0167 0.0156
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0065 0.0231
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.006 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0052 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0167 0.0156
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0167 0.0155
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0052 0.2518
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0167 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Brugia malayi steroid hormone receptor 0.003 0.0167 0.0156
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0167 0.0155
Schistosoma mansoni nuclear receptor 0.0014 0.0052 0.0187
Onchocerca volvulus 0.0014 0.0052 0.2518
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0167 0.0155
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0014 0.005
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0167 0.0595
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0052 0.0187
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Echinococcus granulosus protocadherin 11 0.0009 0.0014 0.005
Loa Loa (eye worm) DR-78 0.0014 0.0052 0.004
Brugia malayi nuclear receptor RXR 0.0014 0.0052 0.0041
Schistosoma mansoni hypothetical protein 0.0176 0.1203 0.4296
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0167 0.0595
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0592 0.2113
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0397 0.0386
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0167 0.0156
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0397 0.1418
Echinococcus granulosus FTZ F1 alpha 0.003 0.0167 0.0595
Echinococcus granulosus GPCR family 2 0.0015 0.006 0.0215
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0298 0.0287
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Schistosoma mansoni hypothetical protein 0.0176 0.1203 0.4296
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0138 0.0126
Onchocerca volvulus 0.0014 0.0052 0.2518
Schistosoma mansoni nuclear hormone receptor 0.003 0.0167 0.0595
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.006 0.0215
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0065 0.0231
Echinococcus multilocularis musashi 0.0026 0.0138 0.0493
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0298 0.0286
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0167 0.0595
Echinococcus granulosus geminin 0.0176 0.1203 0.4296
Onchocerca volvulus 0.0026 0.0138 0.8135
Echinococcus multilocularis protocadherin 11 0.0009 0.0014 0.005
Brugia malayi bZIP transcription factor family protein 0.0009 0.0014 0.0002
Brugia malayi hypothetical protein 0.0016 0.0065 0.0053
Brugia malayi nuclear hormone receptor 0.003 0.0167 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.0215
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0065 0.0052
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0167 0.0595
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0052 0.0187
Schistosoma mansoni cpg binding protein 0.003 0.0162 0.0578
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0052 0.0041
Brugia malayi tailless protein 0.0014 0.0052 0.0041
Brugia malayi hypothetical protein 0.0016 0.0065 0.0053
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0167 0.0155
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0065 0.0231
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0041 0.0146
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0167 0.0595
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0167 0.0156
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.0009 0.0014 0.005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0167 0.0595
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0397 0.1418
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.004
Brugia malayi hypothetical protein 0.0014 0.0052 0.0041
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0167 0.0595
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0167 0.0156
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0052 0.2518
Schistosoma mansoni coup transcription factor 0.003 0.0167 0.0595
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0167 0.0155
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0052 0.0041
Giardia lamblia Hypothetical protein 0.0009 0.0014 0.5
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0167 0.0595
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0167 0.0156
Echinococcus multilocularis lamin dm0 0.0026 0.0138 0.0493
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0052 0.0187
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.005
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.006 0.0048

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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