Detailed information for compound 551377

Basic information

Technical information
  • TDR Targets ID: 551377
  • Name: 3-(4-ethoxyphenyl)-2-methyl-quinazolin-4-one
  • MW: 280.321 | Formula: C17H16N2O2
  • H donors: 0 H acceptors: 1 LogP: 2.77 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)n1c(C)nc2c(c1=O)cccc2
  • InChi: 1S/C17H16N2O2/c1-3-21-14-10-8-13(9-11-14)19-12(2)18-16-7-5-4-6-15(16)17(19)20/h4-11H,3H2,1-2H3
  • InChiKey: JKWBQCHTVBSJDC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(4-ethoxyphenyl)-2-methyl-4-quinazolinone
  • 2-methyl-3-p-phenetyl-quinazolin-4-one
  • 3-(4-ethoxyphenyl)-2-methylquinazolin-4-one
  • lonetil M3
  • 1897-96-7
  • BRN 0255500
  • Lonethyl
  • Oprea1_706624
  • Lonetil
  • EU-0037205
  • 2-Methyl-3-(4'-aethoxyphenyl)chinazolinone(4) [German]
  • 3-(p-Ethoxyphenyl)-2-methyl-4(3H)-quinazolinone
  • 4(3H)-Quinazolinone, 3-(4-ethoxyphenyl)-2-methyl-
  • 4(3H)-Quinazolinone, 3-(p-ethoxyphenyl)-2-methyl-
  • 5-24-03-00146 (Beilstein Handbook Reference)
  • B 146

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0163 0.3724 0.3724
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0597 0.0597
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0597 0.2648
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0606 0.8651
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0606 0.8651
Leishmania major glucose transporter, lmgt1 0.0031 0.0606 0.8651
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Brugia malayi Sugar transporter family protein 0.0101 0.2253 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Entamoeba histolytica protein kinase, putative 0.0031 0.0597 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0318 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0399 0.1769
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0399 0.0603
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0597 0.2648
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0701 1
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0119 0.2978
Onchocerca volvulus 0.0014 0.0201 0.5
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0201 0.2874
Onchocerca volvulus 0.0014 0.0201 0.5
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0201 0.0305
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.2253 0.3408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Brugia malayi Sugar transporter family protein 0.0014 0.0201 0.0894
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0201 0.0894
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Toxoplasma gondii sugar transporter ST3 0.0014 0.0201 0.0305
Echinococcus multilocularis General substrate transporter 0.0087 0.1918 0.851
Onchocerca volvulus 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0597 0.0597
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0701 0.0701
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0163 0.3724 0.5632
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0597 0.2648
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0201 0.0201
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0597 0.0597
Toxoplasma gondii protein kinase, putative 0.0285 0.6612 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0201 0.5052
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0597 0.0597
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0606 0.8651
Loa Loa (eye worm) hypothetical protein 0.0025 0.0448 0.1987
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0597 0.0903
Brugia malayi major facilitator superfamily protein 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0701 0.106
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0597 0.0903
Toxoplasma gondii sugar transporter ST1 0.0014 0.0201 0.0305
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0701 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Leishmania major glucose transporter, lmgt2 0.0031 0.0606 0.8651
Onchocerca volvulus 0.0014 0.0201 0.5
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Toxoplasma gondii sugar transporter ST2 0.0014 0.0201 0.0305
Onchocerca volvulus 0.0014 0.0201 0.5
Schistosoma mansoni glucose transporter 0.0014 0.0201 0.0894
Entamoeba histolytica protein kinase, putative 0.0031 0.0597 1
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0606 0.269
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0597 0.0597
Brugia malayi major facilitator superfamily protein 0.0014 0.0201 0.0894
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0201 0.2874
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0597 0.8517
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0399 1
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Echinococcus granulosus General substrate transporter 0.0087 0.1918 0.851
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0597 0.2648
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Plasmodium vivax CDK-related protein kinase 6, putative 0.0429 1 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0701 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0201 1
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Plasmodium vivax hexose transporter 0.0101 0.2253 0.2253
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0399 0.1769
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0582 0.2583
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Plasmodium falciparum mitogen-activated protein kinase 2 0.0163 0.3724 0.3724
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Schistosoma mansoni glucose transport protein 0.0101 0.2253 1
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0201 0.5052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Brugia malayi Cam kinase protein 1 0.0031 0.0597 0.2648
Trypanosoma cruzi hexose transporter 0.0031 0.0606 0.8651
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0606 0.8651
Onchocerca volvulus Putative transporter 0.0014 0.0201 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.2253 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0606 0.269
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0399 0.1769
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0399 0.6849
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0552 0.2448
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) sugar transporter 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.003 0.0582 0.2583
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0582 0.2583
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0582 0.2583
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0582 0.9752
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0701 1
Entamoeba histolytica hypothetical protein 0.0023 0.0399 0.6679
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0582 0.2583
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0597 0.0597
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0701 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0201 0.6328
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Mycobacterium ulcerans sugar transporter 0.0014 0.0201 0.5052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter 2A 0.0031 0.0606 0.8651
Plasmodium falciparum hexose transporter 0.0101 0.2253 0.2253
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0597 0.0903
Leishmania major protein kinase, putative 0.0031 0.0597 0.8517
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0552 0.2448
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.016 0.0709
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0701 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Plasmodium vivax sugar transporter, putative 0.0014 0.0201 0.0201
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0597 0.0597
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0597 0.0597
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Schistosoma mansoni glucose transport protein 0.0101 0.2253 1
Schistosoma mansoni hypothetical protein 0.0101 0.2253 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0201 0.0894
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0606 0.269
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Plasmodium falciparum protein kinase 7 0.0285 0.6612 0.6612
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0606 0.8651
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0606 0.269
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2253 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0201 0.6328
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Loa Loa (eye worm) hypothetical protein 0.0023 0.0399 0.1769
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Schistosoma mansoni glucose transport protein 0.0101 0.2253 1
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0318 0.5469
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0582 0.2583
Trypanosoma brucei glucose transporter 1E 0.0031 0.0606 0.8651
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0399 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0582 0.2583
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0201 0.5052
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0582 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0318 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0399 0.0399
Onchocerca volvulus 0.0014 0.0201 0.5
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0582 0.2583
Brugia malayi Sugar transporter family protein 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0031 0.0606 0.8651
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0597 0.2648
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0119 1
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0582 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0582 0.2583
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0201 0.0894
Trypanosoma brucei sugar transporter, putative 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Giardia lamblia Hexose transporter 0.0014 0.0201 0.346
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0606 0.8651
Leishmania major glucose transporter, lmgt3 0.0031 0.0606 0.8651
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.2253 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0201 0.0894
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0399 0.0399
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Giardia lamblia Sugar-proton symporter 0.0014 0.0201 0.346
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0399 1
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0119 0.2978
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0606 0.269
Leishmania major hypothetical protein, conserved 0.0014 0.0201 0.2874
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0333 0.1477
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0597 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0017 0.027 0.386
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0606 0.8651
Onchocerca volvulus 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) sugar transporter 0.0101 0.2253 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0597 0.0597
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0399 0.6849
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0606 0.269
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0606 0.269

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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