Detailed information for compound 551378

Basic information

Technical information
  • TDR Targets ID: 551378
  • Name: copper; pyridine-2,3-dicarboxylic acid
  • MW: 230.665 | Formula: C7H5CuNO4
  • H donors: 2 H acceptors: 5 LogP: 0.24 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1ncccc1C(=O)O.[Cu]
  • InChi: 1S/C7H5NO4.Cu/c9-6(10)4-2-1-3-8-5(4)7(11)12;/h1-3H,(H,9,10)(H,11,12);
  • InChiKey: SKKWXCHCOOEOIB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • copper; quinolinic acid
  • 18970-62-2
  • NSC141366
  • 2,3-Pyridinedicarboxylic acid, copper(2+) salt (1:1)
  • NSC141362

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0023 0.0414 0.6679
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0414 0.5783
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 0.5621
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0414 0.0399
Loa Loa (eye worm) hypothetical protein 0.0032 0.0611 0.2648
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 0.5621
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0956
Onchocerca volvulus 0.0014 0.0217 0.5
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0218
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0715 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0612 0.0597
Onchocerca volvulus 0.0014 0.0217 0.5
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0956
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0333 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.868
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0612 0.0597
Schistosoma mansoni protein kinase 0.0032 0.0611 0.2648
Plasmodium falciparum mitogen-activated protein kinase 2 0.0167 0.3734 0.3724
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni glucose transport protein 0.0103 0.2266 1
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0016 0.0468
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0612 0.0597
Plasmodium vivax sugar transporter, putative 0.0014 0.0217 0.0201
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0016 0.0024
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0069
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni protein kinase 0.0032 0.0611 0.2648
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0611 0.855
Plasmodium falciparum protein kinase 7 0.0291 0.6617 0.6612
Entamoeba histolytica protein kinase, putative 0.0032 0.0611 1
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0016 0.0218
Onchocerca volvulus 0.0014 0.0217 0.5
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0414 1
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0414 0.1769
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0217 0.303
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0217 0.303
Mycobacterium ulcerans sugar transporter 0.0014 0.0217 0.5239
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0134 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0621 0.488
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0167 0.3734 0.3724
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0611 0.2648
Plasmodium vivax adenylate kinase 1, putative 0.006 0.1272 0.1259
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Schistosoma mansoni hypothetical protein 0.0103 0.2266 1
Echinococcus granulosus General substrate transporter 0.0089 0.193 0.851
Onchocerca volvulus 0.0014 0.0217 0.5
Trypanosoma brucei sugar transporter, putative 0.0014 0.0217 0.303
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0612 0.0597
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Onchocerca volvulus 0.0014 0.0217 0.5
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0217 0.0201
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.274
Brugia malayi hypothetical protein 0.0014 0.0217 0.0894
Toxoplasma gondii sugar transporter ST2 0.0014 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0025 0.0463 0.1987
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0566 0.2448
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0612 0.0597
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0414 0.3251
Onchocerca volvulus 0.0014 0.0217 0.5
Onchocerca volvulus 0.0014 0.0217 0.5
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0894
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.868
Brugia malayi Sugar transporter family protein 0.0014 0.0217 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.868
Trypanosoma cruzi hexose transporter 0.0032 0.0621 0.868
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0597 0.9752
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0894
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0217 0.0956
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0016 0.0377
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0611 0.2648
Onchocerca volvulus 0.0014 0.0217 0.5
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0217 0.5239
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0612 0.0597
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0217 0.6499
Leishmania major adenylate kinase, putative 0.006 0.1272 1
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0217 0.0327
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0348 0.1536
Toxoplasma gondii adenylate kinase 0.006 0.1272 0.1923
Toxoplasma gondii sugar transporter ST3 0.0014 0.0217 0.0327
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0894
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Brugia malayi hypothetical protein 0.0014 0.0217 0.0894
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0167 0.3734 0.5643
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Onchocerca volvulus 0.0014 0.0217 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0621 0.274
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0612 0.0597
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.868
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0123
Loa Loa (eye worm) sugar transporter 0.0103 0.2266 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0956
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Plasmodium vivax CDK-related protein kinase 6, putative 0.0438 1 1
Onchocerca volvulus 0.0014 0.0217 0.5
Leishmania major hypothetical protein, conserved 0.0014 0.0217 0.1703
Plasmodium falciparum GTP:AMP phosphotransferase 0.006 0.1272 0.1259
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0894
Echinococcus multilocularis General substrate transporter 0.0089 0.193 0.851
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.274
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0894
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0175 0.0709
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0414 0.1769
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0597 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0715 0.1081
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Brugia malayi Cam kinase protein 1 0.0032 0.0611 0.2648
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0597 0.2634
Loa Loa (eye worm) hypothetical protein 0.0023 0.0414 0.1769
Leishmania major glucose transporter, lmgt1 0.0032 0.0621 0.488
Leishmania major glucose transporter, lmgt3 0.0032 0.0621 0.488
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0597 0.2583
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Leishmania major protein kinase, putative 0.0032 0.0611 0.4806
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Trypanosoma brucei glucose transporter 2A 0.0032 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0715 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) sugar transporter 0.0014 0.0217 0.0894
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0134 0.2978
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0414 0.6849
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0597 0.2583
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0414 0.1826
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0612 0.0597
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Plasmodium falciparum hexose transporter 0.0103 0.2266 0.2253
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.2583
Schistosoma mansoni protein kinase 0.0032 0.0611 0.2648
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.2266 0.3424
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0218
Onchocerca volvulus 0.0014 0.0217 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0414 0.1769
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0217 0.0894
Brugia malayi major facilitator superfamily protein 0.0014 0.0217 0.0894
Entamoeba histolytica protein kinase, putative 0.0032 0.0611 1
Schistosoma mansoni glucose transport protein 0.0103 0.2266 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0612 0.0925
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0611 0.2648
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0217 0.0894
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0894
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0414 0.1769
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Brugia malayi Sugar transporter family protein 0.0103 0.2266 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0218
Schistosoma mansoni glucose transporter 0.0014 0.0217 0.0894
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0715 0.0701
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0286 0.3994
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0217 0.5239
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni glucose transport protein 0.0103 0.2266 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0597 0.2583
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0612 0.0925
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0621 0.274
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0612 0.0597
Toxoplasma gondii protein kinase, putative 0.0291 0.6617 1
Plasmodium vivax hexose transporter 0.0103 0.2266 0.2253
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0217 0.303
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0217 0.0894
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0217 0.6499
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0217 0.1703
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 1
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.2266 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.274
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.868
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0597 0.2583
Brugia malayi hypothetical protein 0.0014 0.0217 0.0894
Toxoplasma gondii sugar transporter ST1 0.0014 0.0217 0.0327
Onchocerca volvulus 0.0014 0.0217 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0611 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0611 0.2699
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Leishmania major glucose transporter, lmgt2 0.0032 0.0621 0.488
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.2266 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0956
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0217 1
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0217 0.0894
Onchocerca volvulus 0.0014 0.0217 0.5
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.2583
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0597 0.2583
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0894
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0612 0.0925
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0894
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0597 0.2583
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0217 0.0956
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0333 0.5587
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0414 1
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0414 0.1769
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0016 0.0024
Onchocerca volvulus 0.0014 0.0217 0.5
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0414 0.5783
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Giardia lamblia Sugar-proton symporter 0.0014 0.0217 0.346
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0016 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0621 0.274
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0217 0.0956
Onchocerca volvulus 0.0014 0.0217 0.5
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0621 0.274
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0566 0.2448
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0217 0.5239
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.2266 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.868
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.868
Brugia malayi Sugar transporter family protein 0.0014 0.0217 0.0894
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0333 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0956
Onchocerca volvulus Putative transporter 0.0014 0.0217 0.5
Onchocerca volvulus 0.0014 0.0217 0.5
Giardia lamblia Hexose transporter 0.0014 0.0217 0.346
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0611 0.2648
Brugia malayi major facilitator superfamily protein 0.0014 0.0217 0.0894
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0611 0.2648
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0414 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0016 0.0262
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0217 0.303
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0894
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0414 0.6932
Trypanosoma brucei glucose transporter 1E 0.0032 0.0621 0.868
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0894
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0715 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0956
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0414 0.0399
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0134 0.3243
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0414 0.0625

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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