Detailed information for compound 551408

Basic information

Technical information
  • TDR Targets ID: 551408
  • Name: bis-p-tolyliodonium chloride
  • MW: 344.618 | Formula: C14H14ClI
  • H donors: 0 H acceptors: 0 LogP: 5.88 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)[I+]c1ccc(cc1)C.[Cl-]
  • InChi: 1S/C14H14I.ClH/c1-11-3-7-13(8-4-11)15-14-9-5-12(2)6-10-14;/h3-10H,1-2H3;1H/q+1;/p-1
  • InChiKey: SRMQETMVLPPTFX-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • bis(4-methylphenyl)iodanium chloride
  • bis(4-methylphenyl)iodonium chloride
  • 19028-28-5
  • Toliodium chloride
  • Toliodium chloride [USAN:INN]
  • D06184
  • Toliodium chloride (USAN)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Schistosoma mansoni hypothetical protein 0.0102 0.2253 1
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0597 0.2648
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0201 0.6328
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0582 0.2583
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0318 1
Trypanosoma cruzi hexose transporter 0.0032 0.0606 0.8651
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0597 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Schistosoma mansoni glucose transport protein 0.0102 0.2253 1
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0552 0.2448
Onchocerca volvulus 0.0014 0.0201 0.5
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.016 0.0709
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0701 0.0701
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Brugia malayi Sugar transporter family protein 0.0102 0.2253 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0606 0.269
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Plasmodium vivax sugar transporter, putative 0.0014 0.0201 0.0201
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0201 0.0894
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0201 0.0894
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0606 0.8651
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Toxoplasma gondii protein kinase, putative 0.0287 0.6612 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0606 0.269
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0606 0.269
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0597 0.0597
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0582 0.2583
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0597 0.0597
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0597 0.8517
Entamoeba histolytica protein kinase, putative 0.0031 0.0597 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0399 0.1769
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0701 0.0701
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0701 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0201 0.6328
Onchocerca volvulus 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.2253 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0582 0.2583
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0597 0.2648
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0597 0.0903
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.2253 1
Plasmodium falciparum hexose transporter 0.0102 0.2253 0.2253
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0399 1
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0606 0.8651
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0552 0.2448
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0201 0.5052
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0597 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Loa Loa (eye worm) sugar transporter 0.0014 0.0201 0.0894
Leishmania major hypothetical protein, conserved 0.0014 0.0201 0.2874
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0333 0.1477
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0606 0.8651
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0582 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0017 0.027 0.386
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Schistosoma mansoni glucose transport protein 0.0102 0.2253 1
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0606 0.8651
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0606 0.269
Loa Loa (eye worm) hypothetical protein 0.0023 0.0399 0.1769
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0201 0.0894
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0399 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0606 0.269
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Giardia lamblia Sugar-proton symporter 0.0014 0.0201 0.346
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0399 0.0399
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0119 0.2978
Trypanosoma brucei glucose transporter 1E 0.0032 0.0606 0.8651
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0606 0.8651
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0597 0.0597
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0119 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Giardia lamblia Hexose transporter 0.0014 0.0201 0.346
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0597 0.2648
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0582 0.9752
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0399 0.5689
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0597 0.0597
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0201 0.5052
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0597 0.0903
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0318 1
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Brugia malayi Sugar transporter family protein 0.0014 0.0201 0.0894
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0597 0.0597
Plasmodium falciparum protein kinase 7 0.0287 0.6612 0.6612
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0582 0.2583
Trypanosoma brucei glucose transporter 2A 0.0032 0.0606 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0582 0.2583
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0201 0.0305
Loa Loa (eye worm) sugar transporter 0.0102 0.2253 1
Brugia malayi Sugar transporter family protein 0.0014 0.0201 0.0894
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0399 0.1769
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0399 0.6849
Toxoplasma gondii sugar transporter ST3 0.0014 0.0201 0.0305
Onchocerca volvulus Putative transporter 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Echinococcus multilocularis General substrate transporter 0.0087 0.1918 0.851
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Mycobacterium ulcerans sugar transporter 0.0014 0.0201 0.5052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.2648
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.3724 0.3724
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0701 0.106
Brugia malayi Cam kinase protein 1 0.0031 0.0597 0.2648
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0201 0.0201
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0606 0.269
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0606 0.8651
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0606 0.269
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0318 0.5469
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0399 0.1769
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0399 1
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0582 1
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0119 0.2978
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0701 1
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0201 0.2874
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0201 0.2874
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.3724 0.3724
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0201 0.2874
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0582 0.2583
Leishmania major glucose transporter, lmgt3 0.0032 0.0606 0.8651
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0582 0.2583
Onchocerca volvulus 0.0014 0.0201 0.5
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0597 0.2648
Schistosoma mansoni glucose transport protein 0.0102 0.2253 1
Trypanosoma brucei sugar transporter, putative 0.0014 0.0201 0.2874
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.3724 0.5632
Onchocerca volvulus 0.0014 0.0201 0.5
Onchocerca volvulus 0.0014 0.0201 0.5
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0201 0.0894
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0201 0.5052
Plasmodium vivax hexose transporter 0.0102 0.2253 0.2253
Entamoeba histolytica protein kinase, putative 0.0031 0.0597 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0582 0.2583
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0597 0.0597
Echinococcus granulosus General substrate transporter 0.0087 0.1918 0.851
Leishmania major glucose transporter, lmgt1 0.0032 0.0606 0.8651
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0701 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0201 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0431 1 1
Onchocerca volvulus 0.0014 0.0201 0.5
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2253 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0399 0.1769
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0597 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0201 0.2874
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.2253 0.3408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0399 0.6849
Echinococcus granulosus solute carrier family 22 0.0014 0.0201 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0606 0.8651
Schistosoma mansoni glucose transporter 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Toxoplasma gondii sugar transporter ST2 0.0014 0.0201 0.0305
Echinococcus multilocularis solute carrier family 22 0.0014 0.0201 0.0894
Trypanosoma brucei glucose transporter, putative 0.0032 0.0606 0.8651
Leishmania major glucose transporter, lmgt2 0.0032 0.0606 0.8651
Schistosoma mansoni sugar transporter 0.0014 0.0201 0.0894
Onchocerca volvulus 0.0014 0.0201 0.5
Brugia malayi major facilitator superfamily protein 0.0014 0.0201 0.0894
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0399 0.0603
Loa Loa (eye worm) hypothetical protein 0.0031 0.0582 0.2583
Entamoeba histolytica hypothetical protein 0.0023 0.0399 0.6679
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0597 0.0903
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Loa Loa (eye worm) hypothetical protein 0.0025 0.0448 0.1987
Schistosoma mansoni protein kinase 0.0031 0.0597 0.2648
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0597 0.2648
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0597 0.2648
Brugia malayi major facilitator superfamily protein 0.0014 0.0201 0.0894
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0701 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0201 0.0894
Brugia malayi hypothetical protein 0.0014 0.0201 0.0894
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0701 1
Toxoplasma gondii sugar transporter ST1 0.0014 0.0201 0.0305
Leishmania major protein kinase, putative 0.0031 0.0597 0.8517
Onchocerca volvulus 0.0014 0.0201 0.5
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0597 0.2648
Onchocerca volvulus 0.0014 0.0201 0.5
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0201 0.0894

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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