Detailed information for compound 564060

Basic information

Technical information
  • TDR Targets ID: 564060
  • Name: hydrogen sulfate; (2-hydroxy-4-phenyl-phenyl) ammonium
  • MW: 283.3 | Formula: C12H13NO5S
  • H donors: 3 H acceptors: 5 LogP: 1.05 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]S(=O)(=O)O.Oc1cc(ccc1[NH3+])c1ccccc1
  • InChi: 1S/C12H11NO.H2O4S/c13-11-7-6-10(8-12(11)14)9-4-2-1-3-5-9;1-5(2,3)4/h1-8,14H,13H2;(H2,1,2,3,4)
  • InChiKey: HDLVECNZJJGBDZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • hydrogen sulfate; (2-hydroxy-4-phenylphenyl)ammonium
  • hydrogen sulfate; (2-hydroxy-4-phenyl-phenyl)azanium
  • (2-hydroxy-4-phenyl-phenyl)ammonium bisulfate
  • hydrogen sulfate; (2-hydroxy-4-phenylphenyl)azanium
  • 4363-03-5
  • 73728-82-2
  • 3-BIPHENYLOL, 4-AMINO-, HYDROGEN SULFATE
  • 3-Hydroxy-4-aminodiphenyl sulphate
  • 4-Amino-3-hydroxybiphenyl sulfate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0021 0.0328 0.0772
Schistosoma mansoni hypothetical protein 0.0037 0.0713 0.0698
Mycobacterium ulcerans hypothetical protein 0.0038 0.0733 0.0562
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0733 0.0562
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Schistosoma mansoni cpg binding protein 0.0032 0.0593 0.0578
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0021 0.0328 0.0185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0038 0.0023
Schistosoma mansoni peroxidasin 0.0168 0.3794 0.3785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0243 0.0228
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0072 0.153 0.1516
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0038 0.0023
Brugia malayi beta-lactamase family protein 0.0038 0.0733 0.1849
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0038 0.0023
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0733 0.0562
Brugia malayi beta-lactamase family protein 0.0038 0.0733 0.1849
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0059 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0038 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.7099 1
Schistosoma mansoni cpg binding protein 0.003 0.0552 0.0537
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0243 0.0546
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0038 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0038 0.0023
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0928 0.0855
Loa Loa (eye worm) hypothetical protein 0.0064 0.1353 0.35
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0733 0.1849
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0072 0.153 0.1681
Brugia malayi hypothetical protein 0.003 0.0549 0.1361
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.3794 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.1433 0.142
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.0342 0.7905 0.5
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0549 0.0535
Echinococcus multilocularis dnaJ subfamily B 0.0431 1 1
Brugia malayi Peroxidasin 0.0168 0.3794 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0733 0.0587
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0072 0.153 0.1516
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0733 0.1032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.5553 0.6905
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0038 0.0023
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0306 0.043
Loa Loa (eye worm) TAR-binding protein 0.0053 0.109 0.2802
Brugia malayi beta-lactamase 0.0038 0.0733 0.1849
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0733 0.0718
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0733 0.1032
Brugia malayi Animal haem peroxidase family protein 0.0168 0.3794 1
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0038 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0053 0.109 0.1077
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0306 0.0712
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0733 0.349
Mycobacterium tuberculosis Conserved protein 0.0038 0.0733 0.0562
Schistosoma mansoni tar DNA-binding protein 0.0053 0.109 0.1077
Schistosoma mansoni coup transcription factor 0.0008 0.0038 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.1117 0.2873
Echinococcus granulosus peroxidasin 0.0168 0.3794 0.3785
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0038 0.0023
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0549 0.0535
Schistosoma mansoni hypothetical protein 0.0017 0.0243 0.0228
Brugia malayi Animal haem peroxidase family protein 0.0168 0.3794 1
Echinococcus granulosus transient receptor potential ion channel A 0.0099 0.2169 0.2157
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0038 0.0023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0243 0.0228
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Echinococcus granulosus tar DNA binding protein 0.0053 0.109 0.1077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0038 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0713 0.1796
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Plasmodium falciparum phenylalanine--tRNA ligase 0.0021 0.0328 0.0185
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0021 0.0328 0.0462
Echinococcus granulosus GPCR family 2 0.0017 0.0243 0.0228
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0038 0.0023
Schistosoma mansoni ap endonuclease 0.002 0.0306 0.029
Onchocerca volvulus 0.0038 0.0733 0.1849
Brugia malayi Animal haem peroxidase family protein 0.0168 0.3794 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Schistosoma mansoni hypothetical protein 0.0431 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Onchocerca volvulus Peroxidasin homolog 0.0168 0.3794 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0306 0.043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0733 0.0562
Mycobacterium tuberculosis Conserved protein 0.0038 0.0733 0.0562
Onchocerca volvulus 0.003 0.0552 0.1368
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0059 0.0056
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0021 0.0328 0.0462
Onchocerca volvulus Dual oxidase homolog 0.0168 0.3794 1
Echinococcus multilocularis transient receptor potential ion channel A 0.0099 0.2169 0.2157
Onchocerca volvulus Peroxidase homolog 0.0168 0.3794 1
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0072 0.153 0.1681
Schistosoma mansoni hypothetical protein 0.003 0.0549 0.0535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Onchocerca volvulus Chorion peroxidase homolog 0.0168 0.3794 1
Brugia malayi hypothetical protein 0.0168 0.3794 1
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0072 0.153 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0928 0.0855
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0735 0.1856
Loa Loa (eye worm) hypothetical protein 0.0017 0.0243 0.0546
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.3794 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0733 0.0562
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0072 0.153 0.1802
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0329 0.7587 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0733 0.0587
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.0342 0.7905 1
Mycobacterium ulcerans lipase LipD 0.0038 0.0733 0.0562
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0038 0.0023
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0038 0.0023
Toxoplasma gondii ABC1 family protein 0.0038 0.0733 0.349
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.1433 0.142
Trichomonas vaginalis esterase, putative 0.0038 0.0733 0.1032
Brugia malayi MH2 domain containing protein 0.01 0.2198 0.575
Onchocerca volvulus 0.0038 0.0733 0.1849
Brugia malayi RNA binding protein 0.0053 0.109 0.2802
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0735 0.0721
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0733 0.0562
Schistosoma mansoni peroxidasin 0.0168 0.3794 0.3785
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0306 0.0712
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.1117 0.2873
Echinococcus granulosus transient receptor potential gamma protein 0.0102 0.225 0.2238
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0733 0.0718
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0021 0.0328 0.0313
Loa Loa (eye worm) blistered cuticle protein 3 0.0168 0.3794 1
Loa Loa (eye worm) beta-lactamase 0.0038 0.0733 0.1849
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0549 0.0535
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0038 0.0023
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0156 0.3506 0.4395
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0038 0.0023
Schistosoma mansoni hypothetical protein 0.0017 0.0243 0.0228
Schistosoma mansoni transient receptor potential channel 0.0068 0.1433 0.142
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0038 0.0023
Onchocerca volvulus 0.0168 0.3794 1
Schistosoma mansoni transient receptor potential channel 0.0102 0.225 0.2238
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0038 0.0023
Echinococcus multilocularis peroxidasin 0.0168 0.3794 0.3785
Onchocerca volvulus 0.0168 0.3794 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0655 0.1642
Schistosoma mansoni transient receptor potential channel 4 0.0102 0.225 0.2238
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0038 0.0023
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.1433 0.142
Echinococcus multilocularis transient receptor potential gamma protein 0.0102 0.225 0.2238
Giardia lamblia Fructose-bisphosphate aldolase 0.0308 0.7099 1
Schistosoma mansoni ap endonuclease 0.002 0.0306 0.029
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0038 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0038 0.0023
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0306 0.029
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.3506 0.4395
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0342 0.7905 1
Leishmania major hypothetical protein, conserved 0.0038 0.0733 0.0587
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0021 0.0328 0.0772
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.3385 0.4053
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0038 0.0023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0733 0.0562
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Entamoeba histolytica hypothetical protein 0.003 0.0549 0.0359
Echinococcus multilocularis cpg binding protein 0.0032 0.0593 0.0578
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0733 0.0587
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0733 0.0562
Echinococcus multilocularis tar DNA binding protein 0.0053 0.109 0.1077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Onchocerca volvulus 0.0168 0.3794 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.3506 0.4395
Loa Loa (eye worm) hypothetical protein 0.0054 0.1117 0.2873
Leishmania major mitochondrial DNA polymerase beta 0.0329 0.7587 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0733 0.1032
Brugia malayi TAR-binding protein 0.0053 0.109 0.2802
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0733 0.0718
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0059 0.0044
Brugia malayi Animal haem peroxidase family protein 0.0168 0.3794 1
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0038 0.0023
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0051 0.104 0.1158
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.3385 0.4053
Echinococcus multilocularis GPCR, family 2 0.0017 0.0243 0.0228
Mycobacterium ulcerans hypothetical protein 0.0173 0.392 0.4756
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.1352 0.1338
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0038 0.0023
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0733 0.0718
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0329 0.7587 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0928 0.0855
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0072 0.153 0.1802
Loa Loa (eye worm) RNA binding protein 0.0053 0.109 0.2802
Loa Loa (eye worm) hypothetical protein 0.0102 0.225 0.5888
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0735 0.0721
Schistosoma mansoni tar DNA-binding protein 0.0053 0.109 0.1077
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.0342 0.7905 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0038 0.0023
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0072 0.153 0.3971
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.1433 0.142
Echinococcus granulosus cpg binding protein 0.0032 0.0593 0.0578
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0038 0.0023
Mycobacterium ulcerans beta-lactamase 0.0038 0.0733 0.0562
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0038 0.0023
Brugia malayi Animal haem peroxidase family protein 0.0168 0.3794 1
Brugia malayi RNA recognition motif domain containing protein 0.0053 0.109 0.2802
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0733 0.1849
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0053 0.109 0.2802
Schistosoma mansoni hypothetical protein 0.0017 0.0243 0.0228
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0243 0.0546
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0243 0.0546
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0243 0.0228
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0928 0.0855
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0306 0.029
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0733 0.0562
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.3794 1
Entamoeba histolytica hypothetical protein 0.003 0.0549 0.0359
Loa Loa (eye worm) MH2 domain-containing protein 0.01 0.2198 0.575
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.7099 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0735 0.1856
Mycobacterium tuberculosis Conserved hypothetical protein 0.0173 0.392 0.4756
Onchocerca volvulus Peroxidasin homolog 0.0168 0.3794 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.1166 0.1182
Loa Loa (eye worm) hypothetical protein 0.0072 0.153 0.3971
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0038 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0072 0.153 0.2155
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0072 0.153 0.1681
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0072 0.153 1
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0021 0.0328 0.0313
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0056 0.0048
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0243 0.0228
Schistosoma mansoni transient receptor potential channel 0.0068 0.1433 0.142
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0021 0.0328 0.0185
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0038 0.0023
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0733 0.1032
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0021 0.0328 0.0185
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0038 0.0023
Onchocerca volvulus 0.0038 0.0733 0.1849
Loa Loa (eye worm) hypothetical protein 0.0037 0.0713 0.1796
Brugia malayi CXXC zinc finger family protein 0.003 0.0552 0.1368
Plasmodium falciparum phenylalanine--tRNA ligase 0.0021 0.0328 0.0185
Loa Loa (eye worm) hypothetical protein 0.0038 0.0733 0.1849
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0733 0.0562
Schistosoma mansoni tar DNA-binding protein 0.0053 0.109 0.1077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.119 0.7225
Entamoeba histolytica hypothetical protein 0.003 0.0549 0.0359
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0733 0.0562
Treponema pallidum fructose-bisphosphate aldolase 0.0308 0.7099 1
Onchocerca volvulus Peroxidase homolog 0.0168 0.3794 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.3385 1
Schistosoma mansoni hypothetical protein 0.0017 0.0243 0.0228
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0733 0.1032
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0329 0.7587 1
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0072 0.153 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Entamoeba histolytica hypothetical protein 0.003 0.0549 0.0359
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0072 0.153 0.1802
Schistosoma mansoni cpg binding protein 0.0032 0.0593 0.0578
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0021 0.0328 0.0313
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.1117 0.2873
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.3794 1
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0072 0.153 0.1516
Toxoplasma gondii hypothetical protein 0.0053 0.1088 0.6393
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0021 0.0328 0.0313
Loa Loa (eye worm) transcription factor SMAD2 0.01 0.2198 0.575
Loa Loa (eye worm) hypothetical protein 0.0168 0.3794 1
Brugia malayi Blistered cuticle protein 3 0.0168 0.3794 1
Schistosoma mansoni tar DNA-binding protein 0.0053 0.109 0.1077
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0552 0.1368
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.7099 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.