Detailed information for compound 573272

Basic information

Technical information
  • TDR Targets ID: 573272
  • Name: 3,5-Dioxa-9-thia-4-phosphapentacosan-1-aminiu m, 4-hydroxy-N,N,N-trimethyl-10-oxo-, hydroxi de, inner salt, 4-oxide
  • MW: 495.696 | Formula: C24H50NO5PS
  • H donors: 0 H acceptors: 3 LogP: 7.07 Rotable bonds: 24
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC(=O)SCCCOP(=O)(OCC[N+](C)(C)C)[O-]
  • InChi: 1S/C24H50NO5PS/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-19-24(26)32-23-18-21-29-31(27,28)30-22-20-25(2,3)4/h5-23H2,1-4H3
  • InChiKey: KOCIBOWTCYJTDV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-(1-oxohexadecylthio)propyl 2-(trimethylammonio)ethyl phosphate
  • 3-(1-oxohexadecylthio)propyl 2-trimethylammonioethyl phosphate
  • 3-(hexadecanoylthio)propyl 2-(trimethylammonio)ethyl phosphate
  • 3-(hexadecanoylthio)propyl 2-trimethylammonioethyl phosphate
  • 3-hexadecanoylsulfanylpropyl 2-(trimethylammonio)ethyl phosphate
  • 3-hexadecanoylsulfanylpropyl 2-(trimethylazaniumyl)ethyl phosphate
  • 3-hexadecanoylsulfanylpropyl 2-trimethylazaniumylethyl phosphate
  • 3-hexadecanoylsulfanylpropyl 2-trimethylammonioethyl phosphate
  • 3-Hexadecanoylthio-propane-1-phosphocholine
  • 60793-02-4
  • thiodeoxylysolecithin

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0264 0.0602
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0249 0.5
Schistosoma mansoni hypothetical protein 0.0032 0.0283 0.0753
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0249 0.1346
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0605 0.1608
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0284 0.2998
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0692 0.3264
Plasmodium falciparum phd finger protein, putative 0.0032 0.0264 0.5848
Echinococcus multilocularis muscleblind protein 0.0157 0.3079 0.7015
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0284 0.0648
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0283 0.0283
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.2119 1
Echinococcus granulosus lamin 0.0028 0.0192 0.0438
Brugia malayi PHD-finger family protein 0.0032 0.0264 0.0264
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0284 0.0426
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.1113 0.1113
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0 0.5
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.2927 0.4383
Schistosoma mansoni kinesin eg-5 0.0028 0.0184 0.049
Schistosoma mansoni hypothetical protein 0.0187 0.3761 1
Brugia malayi isocitrate dehydrogenase 0.0032 0.0284 0.0284
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0533 1
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0032 0.0264 0.0264
Onchocerca volvulus 0.0159 0.3119 0.2984
Loa Loa (eye worm) hypothetical protein 0.0157 0.3079 0.3079
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0264 0.0264
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.1126 0.1126
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0558 0.0835
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.2119 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.185 0.185
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.185 0.4215
Giardia lamblia PHD finger protein 15 0.0032 0.0264 0.1429
Loa Loa (eye worm) acetyltransferase 0.0148 0.2878 0.2878
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.2119 0.4829
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0283 0.0645
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.2119 0.2119
Brugia malayi Muscleblind-like protein 0.0157 0.3079 0.3079
Schistosoma mansoni hypothetical protein 0.007 0.1126 0.2994
Brugia malayi MH2 domain containing protein 0.0122 0.2293 0.2293
Loa Loa (eye worm) hypothetical protein 0.0466 1 1
Schistosoma mansoni jumonji domain containing protein 0.0082 0.1398 0.3718
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.2119 0.4829
Leishmania major mitochondrial DNA polymerase beta 0.0317 0.6677 1
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.2293 0.2293
Brugia malayi jmjC domain containing protein 0.0103 0.1875 0.1875
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0192 0.0192
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.1018 0.1018
Echinococcus granulosus GPCR family 2 0.0032 0.0283 0.0645
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0948 0.2867
Echinococcus granulosus kinesin family 1 0.0215 0.4389 1
Echinococcus multilocularis lamin 0.0028 0.0192 0.0438
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0558 0.0835
Toxoplasma gondii hypothetical protein 0.0051 0.0705 0.7436
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0284 0.0648
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.3307 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0249 0.1175
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0317 0.6677 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0284 0.0284
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.1875 0.4271
Onchocerca volvulus 0.0466 1 1
Echinococcus multilocularis kinesin family 1 0.0215 0.4389 1
Brugia malayi Bromodomain containing protein 0.0035 0.0346 0.0346
Schistosoma mansoni kinase 0.0052 0.0722 0.192
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0249 0.4667
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0605 0.1378
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0948 0.2867
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.2293 0.2293
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0284 0.0648
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0605 0.1608
Echinococcus granulosus intermediate filament protein 0.0028 0.0192 0.0438
Echinococcus granulosus lamin dm0 0.0028 0.0192 0.0438
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.185 0.4215
Schistosoma mansoni lamin 0.0028 0.0192 0.0512
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.185 0.185
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0558 0.0835
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0284 0.0284
Plasmodium falciparum kinesin-5 0.0028 0.0184 0.4077
Brugia malayi 6-phosphofructokinase 0.0114 0.2119 0.2119
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0264 0.2788
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0284 0.0426
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.1113 0.1667
Giardia lamblia Kinesin-5 0.0028 0.0184 0.0996
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0777 0.1163
Schistosoma mansoni intermediate filament proteins 0.0028 0.0192 0.0512
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.185 0.277
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.2878 0.2878
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0284 0.0648
Loa Loa (eye worm) hypothetical protein 0.0054 0.077 0.077
Loa Loa (eye worm) hypothetical protein 0.0466 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0283 0.0283
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.2119 0.2119
Echinococcus granulosus muscleblind protein 0.0157 0.3079 0.7015
Loa Loa (eye worm) hypothetical protein 0.0157 0.3079 0.3079
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0452 0.2444
Loa Loa (eye worm) phosphofructokinase 0.0114 0.2119 0.2119
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0249 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.2119 0.5635
Brugia malayi Kinesin motor domain containing protein 0.0028 0.0184 0.0184
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Brugia malayi intermediate filament protein 0.0028 0.0192 0.0192
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0413 0.0942
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Loa Loa (eye worm) hypothetical protein 0.0159 0.3119 0.3119
Brugia malayi phosphofructokinase 0.0114 0.2119 0.2119
Onchocerca volvulus Alhambra homolog 0.0032 0.0264 0.0073
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.2119 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.185 0.8728
Echinococcus multilocularis muscleblind protein 1 0.0157 0.3079 0.7015
Giardia lamblia Kinase, PLK 0.0102 0.185 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0605 0.1378
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.2119 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0249 0.1175
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.1875 0.4271
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.6677 1
Toxoplasma gondii kinesin motor domain-containing protein 0.0028 0.0184 0.1944
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0605 0.0605
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0542 0.1234
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0533 0.5626
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0284 0.2998
Entamoeba histolytica kinesin, putative 0.0028 0.0184 0.087
Echinococcus granulosus peregrin 0.0035 0.0346 0.0788
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0948 0.216
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0533 0.1215
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.185 0.277
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0249 0.5507
Loa Loa (eye worm) kinesin-like protein KLP2 0.0028 0.0184 0.0184
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0413 0.1099
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.2785 0.6346
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0249 0.5507
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0192 0.0192
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.2119 0.3174
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0283 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.185 0.4918
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.2119 0.3174
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.6677 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.1113 0.2536
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0249 0.1175
Loa Loa (eye worm) hypothetical protein 0.0028 0.0192 0.0192
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0283 0.0283
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.1113 0.1667
Brugia malayi hypothetical protein 0.0159 0.3119 0.3119
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0452 0.2133
Plasmodium vivax kinesin-5 0.0028 0.0184 0.3455
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.2119 1
Schistosoma mansoni hypothetical protein 0.0032 0.0264 0.0703
Echinococcus multilocularis musashi 0.0028 0.0192 0.0438
Brugia malayi jmjC domain containing protein 0.0038 0.0413 0.0413
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.1113 0.1113
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0283 0.0645
Trypanosoma brucei polo-like protein kinase 0.0102 0.185 0.277
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0948 0.2521
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.2119 0.5635
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0284 0.0859
Loa Loa (eye worm) hypothetical protein 0.0102 0.1853 0.1853
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0542 0.1234
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0605 0.1378
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0533 0.5626
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0533 0.2517
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0948 0.2867
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0264 0.0703
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.1853 0.1853
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0249 0.2626
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.1113 0.1667
Brugia malayi 6-phosphofructokinase 0.0114 0.2119 0.2119
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0283 0.0645
Echinococcus multilocularis GPCR, family 2 0.0032 0.0283 0.0645
Mycobacterium ulcerans hypothetical protein 0.0167 0.3307 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0533 0.2517
Echinococcus multilocularis Protein lozenge 0.0058 0.0867 0.1975
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.2119 0.3174
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0249 0.4667
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0284 0.0648
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.2878 0.6559
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0948 0.2521
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0284 0.0426
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0457 0.1042
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.2119 1
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0264 0.2788
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.1113 0.1667
Echinococcus granulosus geminin 0.017 0.3366 0.7669
Loa Loa (eye worm) hypothetical protein 0.007 0.1126 0.1126
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.185 0.277
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0284 0.0426
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0283 0.0645
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.2119 1
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0249 0.2626
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0948 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.2878 0.7653
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.1113 0.2536
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0605 0.1608
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.2927 0.4383
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.1113 0.2959
Echinococcus multilocularis geminin 0.017 0.3366 0.7669
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.185 0.8728
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.2119 1
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0413 0.0942
Schistosoma mansoni hypothetical protein 0.0032 0.0283 0.0753
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Schistosoma mansoni hypothetical protein 0.0032 0.0283 0.0753
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0249 0.2626
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0284 0.6288
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0452 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0948 0.216
Schistosoma mansoni hypothetical protein 0.0032 0.0283 0.0753
Loa Loa (eye worm) hypothetical protein 0.0028 0.0181 0.0181
Echinococcus granulosus transcription factor Dp 1 0.004 0.0457 0.1042
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0948 0.142
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.2119 0.6408
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0605 0.1378
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0413 0.1099
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0284 0.0648
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.1853 0.1853
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0413 0.0413
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.2927 0.4383
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.2119 0.6408
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.1853 0.1853
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0249 0.1175
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0284 0.0426
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0284 0.5328
Loa Loa (eye worm) runx1 0.0058 0.0867 0.0867
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0692 0.3264
Echinococcus multilocularis peregrin 0.0035 0.0346 0.0788
Echinococcus multilocularis lamin dm0 0.0028 0.0192 0.0438
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0948 0.2867
Schistosoma mansoni hypothetical protein 0.017 0.3366 0.8949
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0558 0.0835
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0284 0.0756
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0605 0.0605
Schistosoma mansoni hypothetical protein 0.017 0.3366 0.8949
Schistosoma mansoni lamin 0.0028 0.0192 0.0512
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0264 0.4955
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.2119 0.5
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.1113 0.5251
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0264 0.0602
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.185 0.169
Schistosoma mansoni lozenge 0.0058 0.0867 0.2304

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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