Detailed information for compound 574859

Basic information

Technical information
  • TDR Targets ID: 574859
  • Name: N,N-dibutylbutan-1-amine chloride
  • MW: 220.802 | Formula: C12H27ClN-
  • H donors: 0 H acceptors: 0 LogP: 4.82 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN(CCCC)CCCC.[Cl-]
  • InChi: 1S/C12H27N.ClH/c1-4-7-10-13(11-8-5-2)12-9-6-3;/h4-12H2,1-3H3;1H/p-1
  • InChiKey: KLBOFRLEHJAXIU-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • N,N-dibutyl-1-butanamine chloride
  • tributylamine chloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0105 0.0337 0.0329
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.2199
Schistosoma mansoni hypothetical protein 0.0036 0.0084 0.0075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0174 0.0165
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0116 0.038 1
Echinococcus granulosus cpg binding protein 0.003 0.0063 0.0054
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0116 0.038 0.0379
Echinococcus multilocularis potassium channel subfamily K 8 0.0116 0.038 0.0371
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Giardia lamblia Hypothetical protein 0.0116 0.038 1
Schistosoma mansoni hypothetical protein 0.0116 0.038 0.0371
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.2199
Echinococcus granulosus dnaJ subfamily B 0.0404 0.1437 0.1429
Trypanosoma brucei calcium-activated potassium channel, putative 0.0116 0.038 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0021 0.0012
Echinococcus multilocularis dna polymerase eta 0.0019 0.0021 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0009 0.0008
Brugia malayi hypothetical protein 0.0018 0.0017 0.03
Leishmania major hypothetical protein, conserved 0.0116 0.038 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0082 0.2145
Echinococcus multilocularis potassium channel subfamily K 8 0.0116 0.038 0.0371
Schistosoma mansoni calcium-activated potassium channel 0.227 0.829 0.8288
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0075 0.1378
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0084 0.0075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0131 0.013
Schistosoma mansoni DNA polymerase eta 0.0019 0.0021 0.0012
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Onchocerca volvulus 0.0018 0.0017 0.0424
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0084 0.0075
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0082 0.0073
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0116 0.038 0.7075
Loa Loa (eye worm) hypothetical protein 0.0049 0.0131 0.013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0544
Schistosoma mansoni cpg binding protein 0.003 0.0063 0.0054
Schistosoma mansoni polycystin 1-related 0.0018 0.0017 0.0008
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0116 0.038 0.7075
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Brugia malayi hypothetical protein 0.0018 0.0017 0.03
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0021 0.0544
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0021 0.0544
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0082 0.2145
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0082 0.2145
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.015 0.0846
Echinococcus granulosus calcium activated potassium channel variant 0.0116 0.038 0.0371
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0116 0.038 0.7075
Schistosoma mansoni hypothetical protein 0.0018 0.0017 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0082 0.2145
Echinococcus granulosus Polycystic kidney disease protein 0.0018 0.0017 0.0008
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0116 0.038 0.0379
Trypanosoma cruzi ion transport protein, putative 0.0116 0.038 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0021 0.0385
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Schistosoma mansoni cpg binding protein 0.003 0.0063 0.0054
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0116 0.038 0.7075
Toxoplasma gondii ion channel protein 0.0116 0.038 0.3711
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0021 0.0385
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Onchocerca volvulus 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0536 0.0528
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0116 0.038 0.7075
Schistosoma mansoni hypothetical protein 0.0404 0.1437 0.1429
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus granulosus twik family of potassium channels 0.0116 0.038 0.0371
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0116 0.038 0.7075
Onchocerca volvulus 0.0116 0.038 1
Onchocerca volvulus 0.0116 0.038 1
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0021 0.0012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0131 0.2432
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0116 0.038 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0012
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0016
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0001 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Echinococcus multilocularis cpg binding protein 0.003 0.0063 0.0054
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0116 0.038 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0116 0.038 0.7075
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0009 0.0154
Echinococcus multilocularis twik family of potassium channels 0.0116 0.038 0.0371
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Plasmodium falciparum potassium channel 0.0116 0.038 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0017 0.0008
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Trypanosoma cruzi ion transport protein, putative 0.0116 0.038 1
Brugia malayi hypothetical protein 0.0116 0.038 0.7075
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Schistosoma mansoni alpha-glucosidase 0.0137 0.0455 0.0447
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0017 0.0008
Schistosoma mansoni alpha-glucosidase 0.0137 0.0455 0.0447
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0116 0.038 0.0371
Schistosoma mansoni lipoxygenase 0.0073 0.0221 0.0213
Loa Loa (eye worm) hypothetical protein 0.0254 0.0884 0.0884
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0021 0.0544
Schistosoma mansoni loxhd1 0.0018 0.0017 0.0008
Echinococcus multilocularis calcium activated potassium channel variant 0.0116 0.038 0.0371
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0016
Onchocerca volvulus 0.0092 0.029 0.7638
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0082 0.2145
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0082 0.1518
Leishmania major hypothetical protein, conserved 0.0116 0.038 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0536 0.0528
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0116 0.038 0.7075
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0116 0.038 0.7075
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0536 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Loa Loa (eye worm) uncoordinated protein 58 0.0116 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0254 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus granulosus potassium channel subfamily K 8 0.0116 0.038 0.0371
Onchocerca volvulus 0.0018 0.0017 0.0424
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0105 0.0337 0.0329
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0116 0.038 0.0379
Leishmania major DNA polymerase kappa, putative 0.0019 0.0021 0.0544
Schistosoma mansoni hypothetical protein 0.2736 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0544
Echinococcus granulosus microtubule associated protein 2 0.1361 0.4953 0.4948
Loa Loa (eye worm) hypothetical protein 0.1074 0.3896 0.3895
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Leishmania major ion transport protein-like protein 0.0116 0.038 1
Mycobacterium ulcerans transmembrane cation transporter 0.0116 0.038 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0563
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Mycobacterium ulcerans ion transport protein 0.0116 0.038 1
Schistosoma mansoni calcium-activated potassium channel 0.0116 0.038 0.0371
Loa Loa (eye worm) TWK-7 protein 0.0116 0.038 0.0379
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.2859 0.2853
Plasmodium vivax potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) TWK-28 protein 0.0116 0.038 0.0379
Schistosoma mansoni calcium-activated potassium channel 0.0116 0.038 0.0371
Brugia malayi hypothetical protein 0.0116 0.038 0.7075
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Schistosoma mansoni calcium-activated potassium channel 0.2736 1 1
Onchocerca volvulus 0.0116 0.038 1
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0116 0.038 0.0371
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0021 0.0544
Onchocerca volvulus 0.0028 0.0057 0.1476
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Leishmania major DNA polymerase eta, putative 0.0019 0.0021 0.0544
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus multilocularis twik family of potassium channels 0.0116 0.038 0.0371
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.2199
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0116 0.038 0.7075
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Leishmania major potassium channel subunit-like protein 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0349 0.1235 0.1235
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Brugia malayi Doublecortin family protein 0.0018 0.0017 0.03
Echinococcus granulosus twik family of potassium channels 0.0116 0.038 0.0371
Plasmodium vivax potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0254 0.0884 0.0884
Leishmania major calcium/potassium channel (CAKC), putative 0.0116 0.038 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0082 0.2145
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0116 0.038 0.0371
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) doublecortin family protein 0.0018 0.0017 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.1437 0.1429
Echinococcus granulosus dna polymerase eta 0.0019 0.0021 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0082 0.2145
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0082 0.2145
Echinococcus multilocularis microtubule associated protein 2 0.1361 0.4953 0.4948
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0057 0.0056
Trypanosoma brucei glucosidase, putative 0.0035 0.0082 0.2161
Onchocerca volvulus 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.2736 1 1
Onchocerca volvulus 0.0116 0.038 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0017 0.0008
Echinococcus multilocularis potassium channel subfamily K 0.0116 0.038 0.0371
Plasmodium falciparum potassium channel 0.0116 0.038 1
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0116 0.038 0.7075
Toxoplasma gondii hypothetical protein 0.0254 0.0884 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0082 0.2145
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Trypanosoma brucei unspecified product 0.0019 0.0021 0.0563
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0021 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0082 0.2145
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0082 0.2145
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0116 0.038 0.7075
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0084 0.0075
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.1196 0.4347 0.4346
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0254 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Brugia malayi CXXC zinc finger family protein 0.0028 0.0057 0.1044
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Echinococcus granulosus RUN 0.0018 0.0017 0.0008
Schistosoma mansoni alpha glucosidase 0.0035 0.0082 0.0073
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0563
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0536 0.0528
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.2199
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0116 0.038 0.0371
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Schistosoma mansoni lipoxygenase 0.0105 0.0337 0.0329
Echinococcus multilocularis RUN 0.0018 0.0017 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0563
Schistosoma mansoni rab6-interacting 0.0018 0.0017 0.0008
Onchocerca volvulus 0.0116 0.038 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0021 0.0012
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0082 0.2145
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0082 0.2145
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0544
Brugia malayi hypothetical protein 0.0036 0.0084 0.1556
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.038 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0008
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0009 0.0154
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0021 0.0544
Loa Loa (eye worm) hypothetical protein 0.0116 0.038 0.0379
Schistosoma mansoni microtubule-associated protein tau 0.1361 0.4953 0.4948
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.038 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0075 0.0074
Toxoplasma gondii ion channel protein 0.0116 0.038 0.3711
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0033 0.0075 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0116 0.038 0.7075
Schistosoma mansoni cpg binding protein 0.0028 0.0057 0.0048
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0116 0.038 1
Echinococcus granulosus dna polymerase kappa 0.0019 0.0021 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0017 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0544
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0116 0.038 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0536 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0018 0.0017 0.0008
Schistosoma mansoni twik family of potassium channels-related 0.0116 0.038 0.0371
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0116 0.038 0.7075
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0116 0.038 0.7075
Schistosoma mansoni rab6-interacting 0.0018 0.0017 0.0008
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0021 0.0563
Echinococcus granulosus potassium channel subfamily K 0.0116 0.038 0.0371
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0082 0.0073
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0082 0.2145
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0116 0.038 0.7075
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0116 0.038 0.7075
Onchocerca volvulus 0.0116 0.038 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0563
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0131 0.2432
Echinococcus multilocularis small conductance calcium activated potassium 0.2736 1 1
Echinococcus granulosus potassium channel subfamily K 8 0.0116 0.038 0.0371

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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