Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.3211 | 0.347 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.534 | 0.4666 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.3211 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.534 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.534 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.534 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.534 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.7332 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.3211 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0851 | 0.0679 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.7956 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3599 | 0.2673 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.534 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.534 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.534 | 0.577 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.534 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.7332 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.534 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3186 | 0.4076 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3611 | 0.3902 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.3211 | 0.347 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.534 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0851 | 0.0739 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.534 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.534 | 0.577 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3186 | 0.4076 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.534 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.534 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.534 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0518 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9254 | 1 |
Onchocerca volvulus | 0.0048 | 0.534 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.3211 | 0.347 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.3211 | 0.347 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.534 | 0.4666 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0851 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.3211 | 0.347 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.3211 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.534 | 0.577 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.534 | 0.5 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.3211 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4357 | 0.4709 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4024 | 0.4348 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0518 | 0.0559 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.534 | 0.4666 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.