Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0653 | 0.0534 |
Brugia malayi | follicle stimulating hormone receptor | 0.0227 | 0.8828 | 0.8813 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.3332 | 0.3247 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0653 | 0.0753 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.7133 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0653 | 0.0753 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.0091 | 0.2742 | 0.265 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0653 | 0.0753 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.3332 | 0.3247 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0653 | 0.0753 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0099 | 0.3108 | 0.5 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0099 | 0.3108 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0653 | 0.0753 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.0091 | 0.2742 | 0.3735 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.3892 | 0.3815 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0091 | 0.2742 | 1 |
Echinococcus multilocularis | geminin | 0.0189 | 0.7133 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3332 | 0.3247 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0099 | 0.3108 | 0.5 |
Brugia malayi | glucose-6-phosphate dehydrogenase | 0.0091 | 0.2742 | 0.265 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.0091 | 0.2742 | 0.3735 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0241 | 0.9469 | 0.9462 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.0091 | 0.2742 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.1848 | 0.1744 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6495 | 0.4915 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.0091 | 0.2742 | 0.3735 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.3332 | 0.3247 |
Mycobacterium tuberculosis | Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) | 0.0032 | 0.0064 | 0.5 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0091 | 0.2742 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1848 | 0.2458 |
Echinococcus granulosus | geminin | 0.0189 | 0.7133 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0227 | 0.8828 | 0.8813 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.3892 | 0.3815 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0253 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.0091 | 0.2742 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0653 | 0.0534 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0253 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.7133 | 1 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.0091 | 0.2742 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.3892 | 0.3815 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.9469 | 0.9462 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0099 | 0.3108 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0166 | 0.6094 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1848 | 0.1744 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0653 | 0.0753 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0653 | 0.0753 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.0091 | 0.2742 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6495 | 0.4915 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.6094 | 0.4333 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.