Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0165 | 0.1395 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0086 | 0.0555 | 0.0393 |
Schistosoma mansoni | alpha-glucosidase | 0.0894 | 0.916 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0165 | 0.1395 | 0.3943 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0086 | 0.0555 | 0.0393 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0165 | 0.1395 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.098 | 0.0669 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0973 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0299 | 0.2828 | 0.2581 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0086 | 0.0555 | 0.0393 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0241 | 0.221 | 0.2126 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0086 | 0.0555 | 0.0555 |
Echinococcus granulosus | glycogen debranching enzyme | 0.015 | 0.1241 | 0.0938 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0165 | 0.1395 | 0.1098 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.015 | 0.1241 | 0.3291 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0973 | 1 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0165 | 0.1395 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0165 | 0.1395 | 0.3943 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0708 | 0.7184 | 0.7087 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0973 | 1 | 1 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0241 | 0.221 | 0.1941 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5886 |
Trypanosoma brucei | glucosidase, putative | 0.0165 | 0.1395 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0708 | 0.7184 | 0.7761 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0553 | 0.5529 | 0.9073 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0165 | 0.1395 | 1 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0333 | 0.0333 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0299 | 0.2828 | 0.2828 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0708 | 0.7184 | 0.7087 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5375 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0165 | 0.1395 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0165 | 0.1395 | 0.1203 |
Trichomonas vaginalis | glycogen debranching enzyme, putative | 0.015 | 0.1241 | 0.3291 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0165 | 0.1395 | 0.3943 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0207 | 0.1845 | 0.5844 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0086 | 0.0555 | 0.0393 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0165 | 0.1395 | 0.1098 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.0946 | 0.0634 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.098 | 0.0669 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0086 | 0.0555 | 0.0393 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Loa Loa (eye worm) | amylo-alpha-1,6-glucosidase | 0.0073 | 0.042 | 0.0089 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.0946 | 0.0946 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Onchocerca volvulus | 0.0601 | 0.6037 | 1 | |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0241 | 0.221 | 0.1941 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0165 | 0.1395 | 0.3943 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Brugia malayi | Amylo-alpha-1,6-glucosidase family protein | 0.015 | 0.1241 | 0.1241 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5375 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0165 | 0.1395 | 0.3943 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.1375 | 0.1078 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0241 | 0.221 | 0.2126 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.0946 | 0.0634 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0299 | 0.2828 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0196 | 0.1732 | 0.2147 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0165 | 0.1395 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0086 | 0.0555 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1241 | 0.0938 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0973 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0165 | 0.1395 | 0.3943 |
Schistosoma mansoni | alpha-glucosidase | 0.0894 | 0.916 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0086 | 0.0555 | 0.0393 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0165 | 0.1395 | 0.3943 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0333 | 0.0333 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0196 | 0.1732 | 0.5368 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0165 | 0.1395 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0165 | 0.1395 | 0.3943 |
Echinococcus multilocularis | glycogen debranching enzyme | 0.015 | 0.1241 | 0.0938 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5886 |
Brugia malayi | Ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5529 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0251 | 0.231 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.098 | 0.0775 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0241 | 0.221 | 0.1941 |
Entamoeba histolytica | glycogen debranching enzyme, putative | 0.015 | 0.1241 | 0.8162 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0165 | 0.1395 | 0.1395 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0207 | 0.1845 | 0.5844 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0555 | 0.0229 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0553 | 0.5529 | 0.5375 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0333 | 0.0333 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.0796 | 0.0525 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0086 | 0.0555 | 0.0393 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0241 | 0.221 | 0.1941 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0165 | 0.1395 | 0.3943 |
Brugia malayi | hypothetical protein | 0.0126 | 0.098 | 0.098 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.098 | 0.0775 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.1697 | 0.1545 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.