Detailed information for compound 587130

Basic information

Technical information
  • TDR Targets ID: 587130
  • Name: 2-acetoxybenzoic acid; 2-[[2-[bis(2-hydroxyet hyl)amino]-4,8-bis(1-piperidyl)pyrimido[5,4-d ]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethano l
  • MW: 684.783 | Formula: C33H48N8O8
  • H donors: 5 H acceptors: 11 LogP: 1.89 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 3
  • SMILES: CC(=O)Oc1ccccc1C(=O)O.OCCN(c1nc(N2CCCCC2)c2c(n1)c(nc(n2)N(CCO)CCO)N1CCCCC1)CCO
  • InChi: 1S/C24H40N8O4.C9H8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30;1-6(10)13-8-5-3-2-4-7(8)9(11)12/h33-36H,1-18H2;2-5H,1H3,(H,11,12)
  • InChiKey: NOHUXXDTQJPXSB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-acetoxybenzoic acid; 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(1-piperidyl)-6-pyrimido[5,4-d]pyrimidinyl]-(2-hydroxyethyl)amino]ethanol
  • 2-acetyloxybenzoic acid; 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • 2-acetoxybenzoic acid; 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-dipiperidino-pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • aspirin, dipyridamole drug combination
  • 2-acetyloxybenzoic acid; 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-di(piperidin-1-yl)pyrimido[6,5-e]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • 2-acetoxybenzoic acid; 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-bis(1-piperidyl)pyrimido[6,5-e]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • 2-acetoxybenzoic acid; 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-bis(1-piperidyl)-6-pyrimido[6,5-e]pyrimidinyl]-(2-hydroxyethyl)amino]ethanol
  • 2-acetoxybenzoic acid; 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-dipiperidino-pyrimido[6,5-e]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • 87653-67-6
  • TX 3301
  • TX-3301
  • Asasantin
  • Benzoic acid, 2-(acetyloxy)-, mixt. with 2,2',2'',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis(ethanol)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tumor protein p63 0.036 0.4127 0.4115
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.1357 0.5733
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.002 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0056 0.0122
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0056 0.0066
Echinococcus multilocularis geminin 0.0181 0.2035 0.2019
Echinococcus granulosus geminin 0.0181 0.2035 0.2394
Schistosoma mansoni lamin 0.0029 0.0266 0.029
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0056 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0056 0.0122
Echinococcus multilocularis lamin dm0 0.0029 0.0266 0.0247
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0478 0.054
Schistosoma mansoni smad1 5 8 and 0.0008 0.0028 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0056 0.0066
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0093 0.0073
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0056 0.0066
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.1582 0.6703
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0056 0.0044
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0056 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0478 0.054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0028 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0041 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.023 1
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.4514 0.53
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0013 0.0086 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Trypanosoma brucei RNA helicase, putative 0.0202 0.2289 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0056 0.0044
Schistosoma mansoni coup transcription factor 0.0011 0.0056 0.0044
Echinococcus granulosus smad 0.0008 0.0028 0.0033
Schistosoma mansoni hypothetical protein 0.0436 0.501 0.5885
Entamoeba histolytica hypothetical protein 0.0038 0.0378 1
Echinococcus multilocularis microtubule associated protein 2 0.0736 0.85 0.8497
Echinococcus granulosus cyclin dependent kinase 6 0.0394 0.4514 0.5311
Loa Loa (eye worm) hypothetical protein 0.0014 0.0093 0.0278
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0056 0.0122
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0028 0.0033
Echinococcus granulosus lamin dm0 0.0029 0.0266 0.0313
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0056 0.0066
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0695 0.2878
Brugia malayi hypothetical protein 0.0038 0.0378 0.1508
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0056 0.0037
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0687 0.0788
Schistosoma mansoni lamin 0.0029 0.0266 0.029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0695 0.0818
Loa Loa (eye worm) hypothetical protein 0.0142 0.1582 0.6703
Schistosoma mansoni microtubule-associated protein tau 0.0736 0.85 1
Echinococcus multilocularis lamin 0.0029 0.0266 0.0247
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0607 1
Schistosoma mansoni hypothetical protein 0.0066 0.0695 0.0797
Echinococcus multilocularis dnaJ subfamily B 0.0436 0.501 0.5
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0378 0.0359
Brugia malayi hypothetical protein 0.0026 0.023 0.0873
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0056 0.0044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0695 0.0677
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.004 0.0051
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0056 0.0037
Onchocerca volvulus 0.0029 0.0266 0.4285
Leishmania major hypothetical protein, conserved 0.0026 0.023 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0093 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Loa Loa (eye worm) hypothetical protein 0.0029 0.0266 0.1025
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0056 0.0037
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0695 0.0818
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.011 0.0354
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0065 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0127 0.0108
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0695 0.0677
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0056 0.0066
Schistosoma mansoni hypothetical protein 0.0012 0.0065 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0266 0.1025
Schistosoma mansoni cpg binding protein 0.0032 0.0308 0.034
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0056 0.0037
Schistosoma mansoni smad1 5 8 and 0.0008 0.0028 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Entamoeba histolytica hypothetical protein 0.0038 0.0378 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0065 0.0077
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0478 0.1938
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0012 0.5
Entamoeba histolytica hypothetical protein 0.0038 0.0378 1
Entamoeba histolytica hypothetical protein 0.0038 0.0378 1
Echinococcus granulosus dnaJ subfamily B 0.0436 0.501 0.5894
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0056 0.0044
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0056 0.0122
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0056 0.0037
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0056 0.0044
Echinococcus granulosus microtubule associated protein 2 0.0736 0.85 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0056 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0378 0.0444
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0056 0.0122
Brugia malayi STAT protein, DNA binding domain containing protein 0.0168 0.1891 0.8033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0695 0.2878
Schistosoma mansoni hypothetical protein 0.0181 0.2035 0.2377
Echinococcus granulosus cpg binding protein 0.0032 0.0308 0.0362
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0012 0.5
Echinococcus multilocularis GPCR, family 2 0.0066 0.0695 0.0677
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0378 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0056 0.0122
Schistosoma mansoni hypothetical protein 0.0181 0.2035 0.2377
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0545 0.062
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0056 0.0066
Loa Loa (eye worm) hypothetical protein 0.0053 0.0545 0.2229
Loa Loa (eye worm) STAT protein 0.0168 0.1891 0.8033
Echinococcus multilocularis cpg binding protein 0.0032 0.0308 0.0289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0056 0.0122
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0056 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.023 0.0873
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0127 0.0127
Brugia malayi intermediate filament protein 0.0029 0.0266 0.1025
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0695 0.2878
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0041 0.0049
Onchocerca volvulus 0.0031 0.0288 0.473
Brugia malayi steroid hormone receptor 0.0011 0.0056 0.0122
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Onchocerca volvulus 0.0029 0.0266 0.4285
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Echinococcus granulosus GPCR family 2 0.0066 0.0695 0.0818
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0056 0.0122
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.002 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0028 0.0009
Onchocerca volvulus 0.0053 0.0545 1
Schistosoma mansoni cpg binding protein 0.0031 0.0288 0.0316
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0478 0.0562
Echinococcus multilocularis cyclin dependent kinase 6 0.0394 0.4514 0.4503
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.023 0.2155
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0028 0.0033
Echinococcus multilocularis Smad4 0.0008 0.0028 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.023 1
Schistosoma mansoni hypothetical protein 0.0202 0.2289 0.2677
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0056 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0478 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0012 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0056 0.0122
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.2347 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0127 0.0427
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0478 0.0459
Schistosoma mansoni Smad4 0.0008 0.0028 0.001
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0056 0.0044
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.1357 0.5733
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0127 0.0108
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0041 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0478 0.054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0056 0.0122
Brugia malayi CXXC zinc finger family protein 0.0031 0.0288 0.1119
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0056 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0056 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0056 0.0122
Schistosoma mansoni cpg binding protein 0.0032 0.0308 0.034
Brugia malayi ecdysteroid receptor 0.0011 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Brugia malayi hypothetical protein 0.0017 0.0124 0.0415
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0266 0.1025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0012 0.5
Loa Loa (eye worm) hypothetical protein 0.0028 0.026 0.0999
Schistosoma mansoni hypothetical protein 0.0066 0.0695 0.0797
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0056 0.0122
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0056 0.0044
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0288 0.1119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0478 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0056 0.0122
Schistosoma mansoni smad1 5 8 and 0.0008 0.0028 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0056 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0056 0.0122
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0056 0.0044
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0028 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0056 0.0066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0127 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0056 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.023 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.2347 1
Echinococcus multilocularis musashi 0.0029 0.0266 0.0247
Schistosoma mansoni smad 0.0008 0.0028 0.001
Echinococcus granulosus lamin 0.0029 0.0266 0.0313
Brugia malayi nuclear receptor NHR-88 0.0011 0.0056 0.0122
Schistosoma mansoni hypothetical protein 0.0038 0.0378 0.0422
Echinococcus granulosus Smad4 0.0008 0.0028 0.0033
Brugia malayi isocitrate dehydrogenase 0.0017 0.0127 0.0427
Schistosoma mansoni hypothetical protein 0.0066 0.0695 0.0797
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0056 0.0122
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.023 0.0478
Schistosoma mansoni hypothetical protein 0.0142 0.1582 0.1843
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.2347 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.023 1
Brugia malayi nuclear hormone receptor 0.0011 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0207 0.2347 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0056 0.0044
Loa Loa (eye worm) hypothetical protein 0.0066 0.0695 0.2878
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.023 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0056 0.0066
Echinococcus granulosus intermediate filament protein 0.0029 0.0266 0.0313
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0127 0.5
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0127 0.0427
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0056 0.0122
Schistosoma mansoni hypothetical protein 0.0066 0.0695 0.0797
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0056 0.0122
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0122
Brugia malayi MH2 domain containing protein 0.0122 0.1357 0.5733
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0056 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0056 0.0122
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0266 0.1025
Schistosoma mansoni intermediate filament proteins 0.0029 0.0266 0.029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0478 0.1938
Trichomonas vaginalis helicase, putative 0.0007 0.0012 0.5
Echinococcus multilocularis smad 0.0008 0.0028 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0056 0.0037
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.011 0.0354
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0056 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0086 0.0251
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0127 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0056 0.0122
Echinococcus granulosus tumor protein p63 0.036 0.4127 0.4855

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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