Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0044 | 0.3031 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0044 | 0.3031 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0044 | 0.3031 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0044 | 0.3031 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0044 | 0.3031 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0044 | 0.3031 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 1 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.9727 | 0.9727 |
Toxoplasma gondii | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0044 | 0.3031 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0044 | 0.3031 | 0.3031 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0044 | 0.3031 | 0.3031 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.9727 | 0.9727 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0044 | 0.3031 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0044 | 0.3031 | 0.5 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0044 | 0.3031 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 1 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.9727 | 0.9727 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0044 | 0.3031 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0044 | 0.3031 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.