Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0136 | 0.0586 | 0.0571 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0078 | 0.0285 | 0.0235 |
Mycobacterium ulcerans | beta-lactamase | 0.007 | 0.0245 | 0.0457 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0017 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.0245 | 0.0195 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.007 | 0.0245 | 0.0195 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0682 | 0.3406 | 0.3372 |
Schistosoma mansoni | ap endonuclease | 0.0056 | 0.0171 | 0.0162 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0056 | 0.0171 | 0.0121 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.007 | 0.0245 | 0.0457 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.1957 | 1 | 1 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.1957 | 1 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0182 | 0.082 | 0.0806 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.007 | 0.0245 | 0.0457 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0043 | 0.0102 | 0.0093 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0078 | 0.0285 | 0.0235 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0325 | 0.1564 | 0.152 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1957 | 1 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0068 | 0.0233 | 0.0183 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0068 | 0.0017 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0068 | 0.0017 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0068 | 0.0017 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0051 | 0.0036 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0051 | 0.0051 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0068 | 0.0068 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0068 | 0.0017 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0043 | 0.0102 | 0.0051 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.0233 | 0.0183 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0102 | 0.0102 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0723 | 0.0709 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.0233 | 0.0428 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.0245 | 0.0457 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0364 | 0.1765 | 0.1757 |
Echinococcus multilocularis | GPCR, family 2 | 0.0078 | 0.0285 | 0.0269 |
Echinococcus granulosus | cpg binding protein | 0.0182 | 0.082 | 0.0773 |
Plasmodium vivax | hypothetical protein, conserved | 0.007 | 0.0245 | 0.0195 |
Trichomonas vaginalis | helicase, putative | 0.0039 | 0.0083 | 0.0032 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0056 | 0.0171 | 0.0282 |
Chlamydia trachomatis | pyruvate kinase | 0.0033 | 0.0051 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0102 | 0.0102 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.0245 | 0.0195 |
Echinococcus granulosus | geminin | 0.0495 | 0.2443 | 0.2404 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1957 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0285 | 0.0276 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.1957 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0102 | 0.0102 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.0245 | 0.0195 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0163 | 0.0723 | 0.0723 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0246 | 0.1155 | 0.111 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0606 | 0.0597 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.0245 | 0.0237 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0068 | 0.0017 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1957 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0136 | 0.0586 | 0.0586 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.007 | 0.0245 | 0.0457 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0068 | 0.0017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0586 | 0.0577 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0056 | 0.0171 | 0.0121 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0052 | 0.0153 | 0.0102 |
Loa Loa (eye worm) | histone methyltransferase | 0.0053 | 0.0156 | 0.0156 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0136 | 0.0586 | 0.0571 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.0233 | 0.0428 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0068 | 0.0233 | 0.0428 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0053 | 0.0156 | 0.0141 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0449 | 0.2205 | 0.5071 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0078 | 0.0285 | 0.0269 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1957 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Echinococcus multilocularis | 0.1957 | 1 | 1 | |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0068 | 0.0017 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.0723 | 0.0709 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.007 | 0.0245 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0051 | 0.0051 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0586 | 0.0577 |
Echinococcus multilocularis | geminin | 0.0495 | 0.2443 | 0.2431 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0056 | 0.0171 | 0.0121 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.0855 | 0.4299 | 1 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.1957 | 1 | 1 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0051 | 0.0051 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0245 | 0.0195 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0056 | 0.0171 | 0.0121 |
Echinococcus granulosus | dnaJ subfamily B | 0.0823 | 0.4138 | 0.4108 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0823 | 0.4138 | 0.4129 |
Schistosoma mansoni | cpg binding protein | 0.0182 | 0.082 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0136 | 0.0586 | 0.0537 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0056 | 0.0171 | 0.0121 |
Schistosoma mansoni | cpg binding protein | 0.0182 | 0.082 | 0.0812 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0043 | 0.0102 | 0.0051 |
Onchocerca volvulus | 0.0172 | 0.0769 | 1 | |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0172 | 0.0769 | 0.0769 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.1957 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0056 | 0.0171 | 0.0121 |
Trichomonas vaginalis | esterase, putative | 0.007 | 0.0245 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0102 | 0.0093 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0682 | 0.3406 | 0.3396 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.007 | 0.0245 | 0.0457 |
Onchocerca volvulus | 0.0094 | 0.0368 | 0.4414 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.0682 | 0.3406 | 0.34 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0246 | 0.1155 | 0.1155 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0043 | 0.0102 | 0.0087 |
Schistosoma mansoni | cpg binding protein | 0.0172 | 0.0769 | 0.0761 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0586 | 0.0577 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0063 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0752 | 0.0752 |
Mycobacterium tuberculosis | Probable hydrolase | 0.007 | 0.0245 | 0.0457 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Brugia malayi | CXXC zinc finger family protein | 0.0172 | 0.0769 | 0.0722 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.0752 | 0.0744 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0245 | 0.0457 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1957 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0068 | 0.0068 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.0102 | 0.0051 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1957 | 1 | 1 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1957 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0078 | 0.0285 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0051 | 0.0051 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0051 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0068 | 0.0017 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0051 | 0.0042 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.0245 | 0.0237 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1957 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0245 | 0.0195 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0068 | 0.0233 | 0.0183 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1957 | 1 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0056 | 0.0171 | 0.0162 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0056 | 0.0171 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0285 | 0.0276 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0056 | 0.0171 | 0.0121 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0102 | 0.0102 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0068 | 0.0017 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0078 | 0.0285 | 0.0235 |
Onchocerca volvulus | 0.007 | 0.0245 | 0.2702 | |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.1957 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0053 | 0.0156 | 0.0106 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0056 | 0.0171 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.007 | 0.0245 | 0.0457 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.007 | 0.0245 | 0.0457 |
Schistosoma mansoni | hypothetical protein | 0.0823 | 0.4138 | 0.4133 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.0245 | 0.0195 |
Trypanosoma brucei | hypothetical protein, conserved | 0.007 | 0.0245 | 0.0195 |
Brugia malayi | beta-lactamase | 0.007 | 0.0245 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1155 | 0.1155 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0285 | 0.0285 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0056 | 0.0171 | 0.0171 |
Onchocerca volvulus | 0.007 | 0.0245 | 0.2702 | |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0285 | 0.0235 |
Mycobacterium ulcerans | lipase LipD | 0.007 | 0.0245 | 0.0457 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.0245 | 0.0195 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0083 | 0.0032 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0246 | 0.1155 | 0.111 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Toxoplasma gondii | exonuclease III APE | 0.0056 | 0.0171 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0245 | 0.0245 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0285 | 0.0269 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0056 | 0.0171 | 0.0171 |
Mycobacterium leprae | conserved hypothetical protein | 0.007 | 0.0245 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0168 | 0.0752 | 0.0705 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0056 | 0.0171 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.1957 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.007 | 0.0245 | 0.0245 |
Schistosoma mansoni | hypothetical protein | 0.0495 | 0.2443 | 0.2436 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0056 | 0.0171 | 0.0282 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0068 | 0.0017 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0136 | 0.0586 | 0.0537 |
Mycobacterium leprae | Probable lipase LipE | 0.007 | 0.0245 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0606 | 0.0597 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0068 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0495 | 0.2443 | 0.2436 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0245 | 0.0195 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0068 | 0.0053 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0056 | 0.0171 | 0.0156 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0043 | 0.0102 | 0.0087 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0163 | 0.0723 | 0.0675 |
Toxoplasma gondii | ABC1 family protein | 0.007 | 0.0245 | 0.0195 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.007 | 0.0245 | 0.0195 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0136 | 0.0586 | 0.0537 |
Loa Loa (eye worm) | beta-lactamase | 0.007 | 0.0245 | 0.0245 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0056 | 0.0171 | 0.0121 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0163 | 0.0723 | 0.0675 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Onchocerca volvulus | 0.007 | 0.0245 | 0.2702 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.007 | 0.0245 | 0.0457 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.0245 | 0.0195 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0039 | 0.0083 | 0.0032 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0056 | 0.0171 | 0.0121 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0245 | 0.0457 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0051 | 0.0036 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0068 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0102 | 0.0051 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.007 | 0.0245 | 0.023 |
Echinococcus granulosus | GPCR family 2 | 0.0078 | 0.0285 | 0.0235 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0245 | 0.0195 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0068 | 0.0233 | 0.0224 |
Mycobacterium ulcerans | hypothetical protein | 0.0855 | 0.4299 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.0102 | 0.0087 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0285 | 0.0276 |
Mycobacterium tuberculosis | Conserved protein | 0.007 | 0.0245 | 0.0457 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.0233 | 0.0218 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0056 | 0.0171 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0285 | 0.0276 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.0102 | 0.0093 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 6 mg kg-1 | Effective dose required to potentiate yohimbine hydrochloride induced lethality in mice, administered intraperitoneally | ChEMBL. | 4067998 |
ED50 (functional) | = 6.2 mg kg-1 | Effective dose required to prevent reserpine ptosis in mice, administered orally (po) | ChEMBL. | 4067998 |
ED50 (functional) | = 6.8 mg kg-1 | Effective dose required to prevent reserpine ptosis in mice, administered intraperitoneally | ChEMBL. | 4067998 |
LD50 (ADMET) | = 108 mg kg-1 | Lethal dose of the compound was determined in mouse i.p. | ChEMBL. | 4067998 |
LD50 (ADMET) | = 200 mg kg-1 | Lethal dose of the compound was determined in mouse p.o. | ChEMBL. | 4067998 |
Therapeutic index (ADMET) | = 16 | Therapeutic index of the compound administered intraperitoneally in mouse | ChEMBL. | 4067998 |
Therapeutic index (ADMET) | = 32 | Therapeutic index of the compound administered perorally in mouse | ChEMBL. | 4067998 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.