Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0024 | 0.0944 | 0.0944 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0024 | 0.0944 | 0.0944 |
Onchocerca volvulus | 0.0087 | 0.619 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.5687 | 0.5687 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0087 | 0.619 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.619 | 0.619 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0132 | 1 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0024 | 0.0944 | 0.0944 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0024 | 0.0944 | 0.5 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0024 | 0.0944 | 0.0944 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0132 | 1 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0024 | 0.0944 | 0.0944 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0944 | 0.0944 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0024 | 0.0944 | 0.0944 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0024 | 0.0944 | 0.5 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0132 | 1 | 1 |
Onchocerca volvulus | 0.0024 | 0.0944 | 0.1524 | |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0024 | 0.0944 | 0.0944 |
Onchocerca volvulus | 0.0024 | 0.0944 | 0.1524 | |
Onchocerca volvulus | 0.0087 | 0.619 | 1 | |
Echinococcus granulosus | choline O acetyltransferase | 0.0024 | 0.0944 | 0.0944 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0024 | 0.0944 | 0.0944 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0024 | 0.0944 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0087 | 0.619 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.0024 | 0.0944 | 0.0944 |
Onchocerca volvulus | 0.0024 | 0.0944 | 0.1524 | |
Schistosoma mansoni | choline o-acyltransferase | 0.0024 | 0.0944 | 0.1524 |
Onchocerca volvulus | 0.0087 | 0.619 | 1 | |
Schistosoma mansoni | choline o-acyltransferase | 0.0024 | 0.0944 | 0.1524 |
Brugia malayi | Cation transporter family protein | 0.0087 | 0.619 | 0.619 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0024 | 0.0944 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0944 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.619 | 0.619 |
Brugia malayi | Choline O-acetyltransferase | 0.0024 | 0.0944 | 0.0944 |
Onchocerca volvulus | 0.0024 | 0.0944 | 0.1524 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.