Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.6157 | 0.6157 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0948 | 0.0948 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0024 | 0.0948 | 0.0948 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0129 | 1 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.0024 | 0.0948 | 0.0948 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0129 | 1 | 1 |
Onchocerca volvulus | 0.0084 | 0.6157 | 1 | |
Echinococcus multilocularis | choline O acetyltransferase | 0.0024 | 0.0948 | 0.0948 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0024 | 0.0948 | 0.5 |
Schistosoma mansoni | choline o-acyltransferase | 0.0024 | 0.0948 | 0.154 |
Brugia malayi | Choline O-acetyltransferase | 0.0024 | 0.0948 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.5657 | 0.5657 |
Onchocerca volvulus | 0.0024 | 0.0948 | 0.154 | |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0084 | 0.6157 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0024 | 0.0948 | 0.5 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0024 | 0.0948 | 0.5 |
Onchocerca volvulus | 0.0084 | 0.6157 | 1 | |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0129 | 1 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0129 | 1 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0129 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.6157 | 0.6157 |
Onchocerca volvulus | 0.0024 | 0.0948 | 0.154 | |
Onchocerca volvulus | 0.0024 | 0.0948 | 0.154 | |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0024 | 0.0948 | 0.0948 |
Onchocerca volvulus | 0.0024 | 0.0948 | 0.154 | |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0024 | 0.0948 | 0.0948 |
Onchocerca volvulus | 0.0084 | 0.6157 | 1 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0948 | 0.5 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0024 | 0.0948 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 1 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0024 | 0.0948 | 0.5 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0024 | 0.0948 | 0.0948 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0084 | 0.6157 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0024 | 0.0948 | 0.0948 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0024 | 0.0948 | 0.0948 |
Echinococcus granulosus | choline O acetyltransferase | 0.0024 | 0.0948 | 0.0948 |
Schistosoma mansoni | choline o-acyltransferase | 0.0024 | 0.0948 | 0.154 |
Brugia malayi | Cation transporter family protein | 0.0084 | 0.6157 | 0.6157 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.