Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0259 | 0.0259 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0635 | 1 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0635 | 1 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0635 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0116 | 0.1377 | 0.1377 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1377 | 0.1377 |
Onchocerca volvulus | 0.0116 | 0.1377 | 0.5 | |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0116 | 0.1377 | 0.0964 |
Brugia malayi | Choline O-acetyltransferase | 0.0116 | 0.1377 | 0.1377 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0635 | 1 | 1 |
Schistosoma mansoni | choline o-acyltransferase | 0.0116 | 0.1377 | 0.3502 |
Brugia malayi | glutaminase DH11.1 | 0.027 | 0.3931 | 0.3931 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 0.5 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0116 | 0.1377 | 0.0964 |
Schistosoma mansoni | glutaminase | 0.027 | 0.3931 | 1 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0116 | 0.1377 | 0.0964 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0259 | 0.0259 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0116 | 0.1377 | 0.5 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0116 | 0.1377 | 0.5 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0635 | 1 | 1 |
Onchocerca volvulus | 0.0116 | 0.1377 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0635 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0457 | 0.5 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0116 | 0.1377 | 0.1377 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0144 | 0.1831 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.0116 | 0.1377 | 0.0964 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0116 | 0.1377 | 0.0964 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0116 | 0.1377 | 0.0964 |
Mycobacterium ulcerans | glutaminase | 0.027 | 0.3931 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.027 | 0.3931 | 0.3931 |
Loa Loa (eye worm) | glutaminase | 0.027 | 0.3931 | 0.3931 |
Onchocerca volvulus | 0.0116 | 0.1377 | 0.5 | |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0116 | 0.1377 | 0.1377 |
Brugia malayi | Choline O-acetyltransferase | 0.0116 | 0.1377 | 0.1377 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0294 | 0.4334 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0116 | 0.1377 | 0.5 |
Onchocerca volvulus | 0.0116 | 0.1377 | 0.5 | |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0116 | 0.1377 | 0.1377 |
Schistosoma mansoni | choline o-acyltransferase | 0.0116 | 0.1377 | 0.3502 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0144 | 0.1831 | 0.3954 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.4334 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0144 | 0.1831 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0457 | 0.1162 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0116 | 0.1377 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0294 | 0.4334 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0457 | 0.1162 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0116 | 0.1377 | 0.5 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0116 | 0.1377 | 0.1377 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.