Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0646 | 0.386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | alkaline phosphatase | 0.0173 | 0.0823 | 0.2132 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0109 | 0.0417 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0646 | 0.386 | 1 |
Schistosoma mansoni | gliotactin | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | acetylcholinesterase | 0.0109 | 0.0417 | 0.1079 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0109 | 0.0417 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.0291 | 0.0755 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0109 | 0.0417 | 0.0417 |
Brugia malayi | Carboxylesterase family protein | 0.0109 | 0.0417 | 0.1079 |
Brugia malayi | hypothetical protein | 0.047 | 0.2731 | 0.7076 |
Echinococcus multilocularis | alkaline phosphatase | 0.0173 | 0.0823 | 0.0823 |
Echinococcus granulosus | acetylcholinesterase | 0.0646 | 0.386 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0109 | 0.0417 | 0.0417 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0173 | 0.0823 | 0.0823 |
Echinococcus multilocularis | acetylcholinesterase | 0.0646 | 0.386 | 0.386 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Onchocerca volvulus | 0.0109 | 0.0417 | 1 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0646 | 0.386 | 0.386 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0109 | 0.0417 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0173 | 0.0823 | 0.0823 |
Brugia malayi | Carboxylesterase family protein | 0.0646 | 0.386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0109 | 0.0417 | 0.1079 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0025 | 0.0066 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0109 | 0.0417 | 0.1079 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0109 | 0.0417 | 0.1079 |
Onchocerca volvulus | 0.0109 | 0.0417 | 1 | |
Echinococcus granulosus | alkaline phosphatase | 0.0173 | 0.0823 | 0.2132 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0109 | 0.0417 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0025 | 0.0066 |
Echinococcus multilocularis | neuroligin | 0.0109 | 0.0417 | 0.0417 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0173 | 0.0823 | 0.2132 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0646 | 0.386 | 0.386 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Brugia malayi | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0646 | 0.386 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0109 | 0.0417 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0109 | 0.0417 | 0.1079 |
Brugia malayi | Carboxylesterase family protein | 0.0109 | 0.0417 | 0.1079 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0109 | 0.0417 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | survival motor neuron protein | 0.0096 | 0.0331 | 0.0858 |
Loa Loa (eye worm) | carboxylesterase | 0.0646 | 0.386 | 1 |
Onchocerca volvulus | 0.0109 | 0.0417 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0417 | 0.1079 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.047 | 0.2731 | 0.2731 |
Brugia malayi | Carboxylesterase family protein | 0.0646 | 0.386 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0109 | 0.0417 | 0.1079 |
Onchocerca volvulus | 0.0109 | 0.0417 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.0646 | 0.386 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.047 | 0.2731 | 0.7076 |
Schistosoma mansoni | alkaline phosphatase | 0.0173 | 0.0823 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.047 | 0.2731 | 0.7076 |
Echinococcus granulosus | neuroligin | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0109 | 0.0417 | 0.1079 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0025 | 0.0066 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0109 | 0.0417 | 0.1079 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0025 | 0.0066 |
Loa Loa (eye worm) | carboxylesterase | 0.0109 | 0.0417 | 0.1079 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0096 | 0.0331 | 0.0858 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0109 | 0.0417 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.0331 | 0.0858 |
Brugia malayi | Carboxylesterase family protein | 0.0109 | 0.0417 | 0.1079 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0646 | 0.386 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0173 | 0.0823 | 0.0823 |
Brugia malayi | Carboxylesterase family protein | 0.0109 | 0.0417 | 0.1079 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0173 | 0.0823 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.0646 | 0.386 | 1 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0173 | 0.0823 | 0.2132 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0109 | 0.0417 | 0.1079 |
Onchocerca volvulus | 0.0109 | 0.0417 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.