Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0851 | 0.0721 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.2504 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.2504 | 0.2848 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.3194 | 0.3986 |
Echinococcus multilocularis | aldehyde reductase | 0.0023 | 0.0886 | 0.0771 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.3194 | 0.3986 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.7509 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.2504 | 0.2706 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3194 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0851 | 0.0679 |
Brugia malayi | hypothetical protein | 0.0036 | 0.3194 | 0.2209 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.7956 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4024 | 0.4348 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.3194 | 0.3753 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3194 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.2504 | 0.2706 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0518 | 0.0559 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.7509 | 0.9414 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.2504 | 0.142 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldehyde reductase | 0.0023 | 0.0886 | 0.0771 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3186 | 0.3975 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.3186 | 0.3975 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0518 | 0.0242 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.7509 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4357 | 0.4709 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.2504 | 0.2706 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.7509 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9254 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.7509 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.7332 | 0.9752 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.2504 | 0.142 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Trypanosoma brucei | prostaglandin f synthase | 0.0032 | 0.2504 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.2504 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.7332 | 0.9752 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3194 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0032 | 0.2504 | 0.3025 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.2504 | 0.142 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0851 | 0.0721 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.3194 | 0.3753 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.2504 | 0.2706 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.7509 | 0.9414 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3611 | 0.3902 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.7509 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.2504 | 0.2706 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.2504 | 0.3025 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.7509 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.2504 | 0.3025 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.2504 | 0.2706 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.2504 | 0.2848 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3194 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0032 | 0.2504 | 1 |
Onchocerca volvulus | 0.0032 | 0.2504 | 0.5 | |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.2504 | 0.142 |
Schistosoma mansoni | pol-related | 0.0032 | 0.2504 | 0.2848 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.7509 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3599 | 0.2673 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.7509 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.2504 | 0.3025 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0032 | 0.2504 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0032 | 0.2504 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.