TDR Targets

Basic information

Technical information

TDR Targets ID: 792763
Name: 2-[5-(2-fluorophenyl)tetrazol-2-yl]-N-(3-meth ylpent-1-yn-3-yl)acetamide
MW: 301.319 | Formula: C15H16FN5O
H donors: 1 H acceptors: 4 LogP: 2.56 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCC(NC(=O)Cn1nnc(n1)c1ccccc1F)(C#C)C
InChi: 1S/C15H16FN5O/c1-4-15(3,5-2)17-13(22)10-21-19-14(18-20-21)11-8-6-7-9-12(11)16/h1,6-9H,5,10H2,2-3H3,(H,17,22)
InChiKey: AGVIJIGIHNMPKY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-(1-ethyl-1-methyl-prop-2-ynyl)-2-[5-(2-fluorophenyl)tetrazol-2-yl]acetamide
N-(1-ethyl-1-methylprop-2-ynyl)-2-[5-(2-fluorophenyl)-2-tetrazolyl]acetamide
2-[5-(2-fluorophenyl)-1,2,3,4-tetrazol-2-yl]-N-(3-methylpent-1-yn-3-yl)ethanamide
A3756/0159270

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	STE group serine/threonine-protein kinase, putative	0.0028	0.0123	0.3735
Schistosoma mansoni	patched 1	0.0042	0.0296	0.1524
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0389	0.1204
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Loa Loa (eye worm)	hypothetical protein	0.0234	0.28	0.8672
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0255	0.3081	0.9542
Echinococcus granulosus	tumor protein p63	0.0334	0.4108	1
Loa Loa (eye worm)	CAMK/CAMKL/PASK protein kinase	0.0267	0.3229	1
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	0.5
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	voltage-gated potassium channel	0.0027	0.0099	0.051
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0296	0.0916
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	0.5
Schistosoma mansoni	60S ribosomal protein L21	0.0027	0.0099	0.051
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0063	0.0568	0.0568
Onchocerca volvulus		0.0267	0.3229	1
Schistosoma mansoni	hypothetical protein	0.0168	0.1942	1
Echinococcus granulosus	Niemann Pick C1 protein	0.0139	0.1565	0.3811
Schistosoma mansoni	hypothetical protein	0.0063	0.0568	0.2923
Echinococcus granulosus	Niemann Pick C1 protein	0.0097	0.1021	0.2484
Echinococcus multilocularis	Niemann Pick C1 protein	0.0139	0.1565	0.1565
Brugia malayi	Niemann-Pick C1 protein precursor	0.0097	0.1021	0.3312
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Schistosoma mansoni	hypothetical protein	0.0063	0.0568	0.2923
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	peptidase Clp S14 family	0.005	0.0399	0.0971
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	1
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Loa Loa (eye worm)	hypothetical protein	0.0198	0.2331	0.7219
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0063	0.0568	0.1382
Schistosoma mansoni	hypothetical protein	0.0027	0.0099	0.051
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0198	0.2331	0.7566
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0089	0.0919	0.4734
Entamoeba histolytica	hypothetical protein	0.007	0.067	0.6562
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0031	0.0157	0.1006
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	sterol regulatory element binding protein	0.0042	0.0296	0.0296
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	conserved hypothetical protein	0.0042	0.0296	0.096
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0089	0.0919	0.4734
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	voltage-gated potassium channel	0.0027	0.0099	0.051
Trichomonas vaginalis	guanylate cyclase beta 2 subunit, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	hypothetical protein	0.0168	0.1942	1
Echinococcus multilocularis	GPCR, family 2	0.0063	0.0568	0.0568
Trichomonas vaginalis	hypothetical protein	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0042	0.0296	0.0916
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0076	0.074	0.074
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0076	0.074	1
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0076	0.074	1
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0076	0.074	0.18
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	hypothetical protein	0.004	0.0276	0.1423
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0027	0.0099	0.0099
Echinococcus granulosus	voltage gated potassium channel	0.0027	0.0099	0.0241
Trichomonas vaginalis	adenylate cyclase type, putative	0.0027	0.0099	0.0321
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0076	0.074	1
Schistosoma mansoni	voltage-gated potassium channel	0.0027	0.0099	0.051
Echinococcus multilocularis	tumor protein p63	0.0334	0.4108	0.4108
Brugia malayi	latrophilin 2 splice variant baaae	0.0135	0.1515	0.4917
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0076	0.074	0.229
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.2054	0.6665
Echinococcus multilocularis	Niemann Pick C1 protein	0.0097	0.1021	0.1021
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.2054	0.6665
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0076	0.074	1
Echinococcus granulosus	geminin	0.0168	0.1942	0.4726
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	0.5
Echinococcus granulosus	expressed conserved protein	0.0091	0.0944	0.2297
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	expressed conserved protein	0.0091	0.0944	0.0944
Trichomonas vaginalis	guanylate cyclase beta 1 subunit, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0198	0.2331	0.7566
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0097	0.1021	1
Echinococcus multilocularis	peptidase Clp (S14 family)	0.005	0.0399	0.0399
Entamoeba histolytica	hypothetical protein	0.007	0.067	0.6562
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Trypanosoma cruzi	DNA polymerase eta, putative	0.0044	0.0328	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Leishmania major	DNA polymerase eta, putative	0.0044	0.0328	1
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0063	0.0568	0.1842
Onchocerca volvulus		0.0049	0.0389	0.0055
Echinococcus granulosus	sterol regulatory element binding protein	0.0042	0.0296	0.072
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Giardia lamblia	DINP protein human, muc B family	0.0019	0	0.5
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.007	0.067	0.067
Brugia malayi	Probable ClpP-like protease	0.0076	0.074	0.24
Echinococcus granulosus	Protein patched homolog 1	0.0042	0.0296	0.072
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0027	0.0099	0.0321
Trypanosoma cruzi	DNA polymerase eta, putative	0.0031	0.0157	0.4775
Echinococcus multilocularis	dna polymerase eta	0.0044	0.0328	0.0328
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0089	0.0919	0.2237
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	survival motor neuron protein 1	0.0234	0.28	0.28
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	protein dispatched 1	0.0048	0.0373	0.0373
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Trichomonas vaginalis	adenylate cyclase type VI, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0089	0.0919	0.4734
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	1
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	1
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	hypothetical protein	0.004	0.0276	0.1423
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	transcription factor LCR-F1	0.007	0.067	0.345
Schistosoma mansoni	survival motor neuron protein	0.0048	0.0373	0.1922
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0063	0.0568	0.0568
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0099	0.0307
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Schistosoma mansoni	hypothetical protein	0.0135	0.1515	0.7803
Schistosoma mansoni	cellular tumor antigen P53	0.0049	0.0389	0.2003
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.007	0.067	0.163
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0063	0.0568	0.1382
Schistosoma mansoni	voltage-gated potassium channel	0.0027	0.0099	0.051
Schistosoma mansoni	voltage-gated potassium channel	0.0027	0.0099	0.051
Entamoeba histolytica	hypothetical protein	0.007	0.067	0.6562
Trichomonas vaginalis	adenylate cyclase type, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0099	0.104	0.5358
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0027	0.0099	0.0321
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0063	0.0568	0.1757
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0027	0.0099	0.0241
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0048	0.0373	0.1211
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0076	0.074	1
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0089	0.0919	0.2846
Trichomonas vaginalis	adenylate cyclase type III, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0089	0.0919	0.2237
Trichomonas vaginalis	adenylate cyclase type vIII, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0198	0.2331	0.7219
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.005	0.0399	1
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.005	0.0399	1
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0255	0.3081	1
Trichomonas vaginalis	intestinal guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0089	0.0919	0.0919
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Brugia malayi	hypothetical protein	0.0234	0.28	0.9088
Schistosoma mansoni	hypothetical protein	0.004	0.0276	0.1423
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase type, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0097	0.1021	0.3161
Brugia malayi	Latrophilin receptor protein 2	0.0063	0.0568	0.1842
Trypanosoma brucei	DNA polymerase eta, putative	0.0044	0.0328	1
Schistosoma mansoni	hypothetical protein	0.0063	0.0568	0.2923
Mycobacterium leprae	Possible transporter protein	0.0027	0.0099	0.0113
Brugia malayi	CHE-14 protein	0.0042	0.0296	0.096
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0135	0.1515	0.4691
Schistosoma mansoni	DNA polymerase eta	0.0044	0.0328	0.1692
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Echinococcus granulosus	GPCR family 2	0.0063	0.0568	0.1382
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0089	0.0919	0.2983
Brugia malayi	aryl hydrocarbon receptor nuclear translocator protein, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Brugia malayi	hypothetical protein	0.007	0.067	0.2174
Trichomonas vaginalis	glucosylceramidase, putative	0.0167	0.1936	0.6284
Brugia malayi	ImpB/MucB/SamB family protein	0.0044	0.0328	0.1066
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Leishmania major	DNA polymerase eta, putative	0.0031	0.0157	0.4775
Schistosoma mansoni	hypothetical protein	0.0048	0.0373	0.1922
Echinococcus multilocularis	voltage gated potassium channel	0.0027	0.0099	0.0099
Echinococcus multilocularis	protein patched	0.0042	0.0296	0.0296
Entamoeba histolytica	hypothetical protein	0.007	0.067	0.6562
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	single minded 2	0.0027	0.0099	0.0241
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0089	0.0919	0.0919
Echinococcus granulosus	dna polymerase eta	0.0044	0.0328	0.08
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0099	0.0321
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylyl cyclase type V, putative	0.0027	0.0099	0.0321
Trichomonas vaginalis	adenylate cyclase type III, putative	0.0027	0.0099	0.0321
Schistosoma mansoni	hypothetical protein	0.007	0.067	0.345
Trichomonas vaginalis	adenylate cyclase, putative	0.0027	0.0099	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0568	0.1757
Schistosoma mansoni	hypothetical protein	0.0063	0.0568	0.2923
Trichomonas vaginalis	glucosylceramidase, putative	0.0255	0.3081	1
Schistosoma mansoni	peptidase Clp (S14 family)	0.0076	0.074	0.3809
Onchocerca volvulus	Glucosylceramidase homolog	0.0167	0.1936	0.5472
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0328	0.1017
Trichomonas vaginalis	guanylate cyclase, putative	0.0027	0.0099	0.0321
Echinococcus granulosus	survival motor neuron protein 1	0.0234	0.28	0.6816
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0419	0.1296
Echinococcus multilocularis	geminin	0.0168	0.1942	0.1942
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.005	0.0399	0.4744
Schistosoma mansoni	hypothetical protein	0.004	0.0276	0.1423

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 792763