TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 401.458 | Formula: C24H23N3O3
H donors: 0 H acceptors: 2 LogP: 4.42 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)N1CCN(CC1)C(=O)c1cc2c(o1)nc1c(c2)ccc(c1)C
InChi: 1S/C24H23N3O3/c1-16-3-4-17-14-18-15-22(30-23(18)25-21(17)13-16)24(28)27-11-9-26(10-12-27)19-5-7-20(29-2)8-6-19/h3-8,13-15H,9-12H2,1-2H3
InChiKey: ZPAHWRXIYSFPRN-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0053	0.0051	0.1135
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Echinococcus granulosus	orexin receptor type 2	0.0053	0.0051	0.1318
Echinococcus multilocularis	neuropeptide s receptor	0.0053	0.0051	0.1318
Trypanosoma cruzi	GDP-mannose pyrophosphorylase	0.0034	0.0024	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	zgc:92842	0.0033	0.0022	0.0494
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.0051	0.1318
Plasmodium vivax	hypothetical protein, conserved	0.0033	0.0022	0.8405
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Trypanosoma cruzi	hypothetical protein, conserved	0.0033	0.0022	0.8405
Echinococcus granulosus	g protein coupled receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	neuropeptide receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	orexin receptor type 2	0.0053	0.0051	0.1318
Leishmania major	GDP-mannose pyrophosphorylase	0.0034	0.0024	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Toxoplasma gondii	eukaryotic initiation factor 2B epsilon subunit, putative	0.0033	0.0022	0.0048
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	neuropeptide F-like receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	somatostatin receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	geminin	0.0185	0.0242	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0054	0.0053	0.1174
Brugia malayi	putative neuropeptide receptor NPR1	0.0053	0.0051	0.1135
Echinococcus granulosus	g-protein coupled receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	mannose-1-phosphate guanyltransferase	0.0034	0.0024	0.0071
Brugia malayi	Dopamine receptor protein 2	0.0053	0.0051	0.1135
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.0051	0.1318
Trypanosoma brucei	hypothetical protein, conserved	0.0033	0.0022	0.8405
Mycobacterium ulcerans	molybdopterin-guanine dinucleotide biosynthesis protein A	0.1206	0.1715	0.1697
Schistosoma mansoni	hypothetical protein	0.0053	0.0051	0.1318
Mycobacterium tuberculosis	Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU	0.6945	1	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.0051	0.1318
Brugia malayi	MH2 domain containing protein	0.013	0.0163	0.3606
Chlamydia trachomatis	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	0.0033	0.0022	0.5
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Trypanosoma cruzi	GDP-mannose pyrophosphorylase	0.0034	0.0024	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Giardia lamblia	Translation initiation factor	0.0033	0.0022	0.5
Echinococcus multilocularis	g-protein coupled receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0053	0.0051	0.1318
Schistosoma mansoni	amine GPCR	0.0053	0.0051	0.1318
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0033	0.0022	0.0494
Loa Loa (eye worm)	MH2 domain-containing protein	0.013	0.0163	0.34
Brugia malayi	neuropeptide F receptor	0.0053	0.0051	0.1135
Echinococcus granulosus	neuropeptide receptor	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Brugia malayi	G protein-coupled receptor F59B2.13	0.0053	0.0051	0.1135
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Brugia malayi	ORL1-like opioid receptor	0.0053	0.0051	0.1135
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0053	0.0051	0.1318
Schistosoma mansoni	hypothetical protein	0.0037	0.0028	0.0265
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0053	0.0051	0.1318
Leishmania major	hypothetical protein, conserved	0.0033	0.0022	0.8405
Schistosoma mansoni	biogenic amine receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Toxoplasma gondii	hypothetical protein	0.0033	0.0022	0.0048
Brugia malayi	RE15519p	0.0053	0.0051	0.1135
Toxoplasma gondii	GDP-D-mannose pyrophosphorylase	0.0034	0.0024	0.0057
Echinococcus granulosus	g protein coupled receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Schistosoma mansoni	biogenic amine receptor	0.0053	0.0051	0.1318
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0053	0.0051	0.1135
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Brugia malayi	putative neuropeptide receptor	0.0053	0.0051	0.1135
Loa Loa (eye worm)	TYRA-2 protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0022	0.0187
Brugia malayi	hypothetical protein	0.0028	0.0014	0.0312
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0053	0.0051	0.0849
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0053	0.0051	0.1135
Leishmania major	hypothetical protein, conserved	0.0033	0.0022	0.8405
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0053	0.0051	0.1318
Loa Loa (eye worm)	nucleotidyl transferase	0.0034	0.0024	0.0223
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0053	0.0051	0.1135
Schistosoma mansoni	opsin-like receptor	0.0053	0.0051	0.1318
Leishmania major	serine acetyltransferase	0.0033	0.0022	0.8405
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Trichomonas vaginalis	sugar-1-phosphate guanyl transferase, putative	0.0034	0.0024	1
Trypanosoma cruzi	serine acetyltransferase, putative	0.0033	0.0022	0.8405
Trypanosoma brucei	GDP-mannose pyrophosphorylase	0.0034	0.0024	1
Toxoplasma gondii	eukaryotic initiation factor-2B, epsilon subunit, putative	0.0033	0.0022	0.0048
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Brugia malayi	neuropeptide F receptor	0.0053	0.0051	0.1135
Schistosoma mansoni	neuropeptide receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Chlamydia trachomatis	UDP-3-O-acylglucosamine N-acyltransferase	0.0033	0.0022	0.5
Mycobacterium ulcerans	hypothetical protein	0.1206	0.1715	0.1697
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.033	0.0451	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	mannose 1 phosphate guanyltransferase beta	0.0034	0.0024	0.0071
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0053	0.089
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0022	0.0187
Leishmania major	hypothetical protein, conserved	0.0033	0.0022	0.8405
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.0051	0.0849
Echinococcus granulosus	serotonin receptor	0.0053	0.0051	0.1318
Brugia malayi	Serotonin receptor	0.0053	0.0051	0.1135
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	growth hormone secretagogue receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	neuropeptides capa receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	glucosamine-1-phosphate N-acetyltransferase	0.0034	0.0024	0.0071
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	GDP-mannose pyrophosphorylase B	0.0033	0.0022	0.0187
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0053	0.0051	0.1135
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Brugia malayi	GDP-mannose pyrophosphorylase B	0.0034	0.0024	0.0528
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0033	0.0022	0.0494
Echinococcus granulosus	G protein coupled receptor 139	0.0053	0.0051	0.1318
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	neuropeptide F receptor	0.0053	0.0051	0.0849
Onchocerca volvulus		0.033	0.0451	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	transcription factor SMAD2	0.013	0.0163	0.34
Echinococcus multilocularis	allatostatin A receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	serotonin receptor	0.0053	0.0051	0.1318
Brugia malayi	larval opioid receptor	0.0053	0.0051	0.1135
Schistosoma mansoni	adenoreceptor	0.0053	0.0051	0.1318
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	allatostatin A receptor	0.0053	0.0051	0.1318
Brugia malayi	Serotonin receptor	0.0053	0.0051	0.1135
Brugia malayi	hypothetical protein	0.0033	0.0022	0.0494
Loa Loa (eye worm)	melatonin receptor type 1A	0.0053	0.0051	0.0849
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	amine GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	sex peptide receptor	0.0053	0.0051	0.1318
Mycobacterium ulcerans	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	0.6945	1	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0033	0.0022	0.8405
Schistosoma mansoni	opsin-like receptor	0.0053	0.0051	0.1318
Wolbachia endosymbiont of Brugia malayi	N-acetylglucosamine-1-phosphate uridyltransferase	0.6945	1	1
Echinococcus granulosus	hypothetical protein	0.0053	0.0051	0.1318
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0053	0.0051	0.0849
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.0051	0.0849
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	gdp-mannose pyrophosphorylase b isoform 2	0.0034	0.0024	0.0071
Brugia malayi	G-protein coupled receptor	0.0053	0.0051	0.1135
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0053	0.0051	0.1318
Trichomonas vaginalis	glucose-1-phosphate thymidylyltransferase, putative	0.0034	0.0024	1
Echinococcus multilocularis	mannose 1 phosphate guanyltransferase	0.0034	0.0024	0.0071
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0053	0.0051	0.1135
Echinococcus multilocularis	neuropeptide receptor A26	0.0053	0.0051	0.1318
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.0051	0.1318
Echinococcus granulosus	somatostatin receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	hypothetical protein	0.0185	0.0242	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Schistosoma mansoni	histamine h1 receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Mycobacterium ulcerans	d-alpha-D-mannose-1-phosphate guanylyltransferase ManB	0.0034	0.0024	0.0002
Loa Loa (eye worm)	GDP-mannose pyrophosphorylase B	0.0034	0.0024	0.0223
Brugia malayi	Dopamine receptor	0.0053	0.0051	0.1135
Echinococcus multilocularis	sex peptide receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Trypanosoma brucei	hypothetical protein, conserved	0.0033	0.0022	0.8405
Echinococcus granulosus	neuropeptides capa receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	amine GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	hypothetical protein	0.0053	0.0051	0.1318
Trypanosoma brucei	nucleotidyl transferase, putative	0.0034	0.0024	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	G-protein coupled receptor	0.0053	0.0051	0.1135
Plasmodium falciparum	mannose-1-phosphate guanyltransferase, putative	0.0034	0.0024	1
Brugia malayi	eIF4-gamma/eIF5/eIF2-epsilon family protein	0.0033	0.0022	0.0494
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0053	0.0051	0.1318
Echinococcus multilocularis	serotonin receptor	0.0053	0.0051	0.1318
Plasmodium falciparum	dynactin subunit 5, putative	0.0033	0.0022	0.8405
Schistosoma mansoni	amine GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.0051	0.1318
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	AKH receptor	0.0053	0.0051	0.1135
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0053	0.0051	0.1318
Brugia malayi	Nucleotidyl transferase family protein	0.0034	0.0024	0.0528
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	neuropeptide receptor	0.0053	0.0051	0.1318
Brugia malayi	GnHR receptor homolog	0.0053	0.0051	0.1135
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	follicle stimulating hormone receptor	0.0053	0.0051	0.1135
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	latrophilin 2 splice variant baaae	0.0037	0.0028	0.0623
Echinococcus granulosus	neuropeptide FF receptor 2	0.0053	0.0051	0.1318
Echinococcus granulosus	geminin	0.0185	0.0242	1
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0053	0.0051	0.1318
Echinococcus granulosus	7TM GPCR rhodopsin	0.0053	0.0051	0.1318
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Trypanosoma cruzi	hypothetical protein	0.0033	0.0022	0.8405
Schistosoma mansoni	opsin-like receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	sulfakinin receptor protein	0.0053	0.0051	0.1135
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.0051	0.1318
Trypanosoma cruzi	hypothetical protein, conserved	0.0033	0.0022	0.8405
Treponema pallidum	licC protein (licC)	0.1206	0.1715	0.5
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	g protein coupled receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	dynactin 5	0.0033	0.0022	0.0187
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0054	0.0053	0.089
Echinococcus granulosus	g protein coupled receptor	0.0053	0.0051	0.1318
Plasmodium falciparum	liver specific protein 2, putative	0.0033	0.0022	0.8405
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0053	0.0051	0.1318
Echinococcus granulosus	fmrfamide receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Mycobacterium tuberculosis	Conserved hypothetical protein	0.1206	0.1715	0.1697
Echinococcus granulosus	dro:myosuppressin receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0053	0.0051	0.0849
Echinococcus multilocularis	fmrfamide receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	mannose 1 phosphate guanyltransferase	0.0034	0.0024	0.0071
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.0051	0.1318
Trypanosoma cruzi	serine acetyltransferase, putative	0.0033	0.0022	0.8405
Plasmodium vivax	dynactin subunit 5, putative	0.0033	0.0022	0.8405
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Mycobacterium ulcerans	hypothetical protein	0.1206	0.1715	0.1697
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	hypothetical protein	0.0053	0.0051	0.1318
Toxoplasma gondii	eukaryotic initiation factor-2B, gamma subunit, putative	0.1206	0.1715	1
Schistosoma mansoni	amine GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	biogenic amine receptor	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Echinococcus granulosus	neuropeptide Y receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	neuropeptide s receptor	0.0053	0.0051	0.1318
Trypanosoma brucei	hypothetical protein, conserved	0.0033	0.0022	0.8405
Schistosoma mansoni	neuropeptide receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0053	0.0051	0.1135
Schistosoma mansoni	hypothetical protein	0.0185	0.0242	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Mycobacterium tuberculosis	Conserved hypothetical protein	0.1206	0.1715	0.1697
Trypanosoma cruzi	Translation initiation factor eIF-2B subunit epsilon, putative	0.0034	0.0024	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0053	0.0051	0.0849
Plasmodium vivax	mannose-1-phosphate guanyltransferase, putative	0.0034	0.0024	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0053	0.0051	0.0849
Brugia malayi	Melatonin receptor type 1A	0.0053	0.0051	0.1135
Echinococcus multilocularis	dro:myosuppressin receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0028	0.032
Schistosoma mansoni	neuropeptide receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	biogenic amine 5HT receptor	0.0053	0.0051	0.1318
Echinococcus granulosus	neuropeptide receptor	0.0053	0.0051	0.1318
Echinococcus multilocularis	G protein coupled receptor 139	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Schistosoma mansoni	neuropeptide f receptor 76f	0.0053	0.0051	0.1318
Schistosoma mansoni	hypothetical protein	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0054	0.0053	0.1174
Echinococcus granulosus	neuropeptide receptor A26	0.0053	0.0051	0.1318
Brugia malayi	Dopamine receptor protein 1	0.0053	0.0051	0.1135
Echinococcus granulosus	mannose 1 phosphate guanyltransferase beta	0.0034	0.0024	0.0071
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0053	0.0051	0.1318
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.033	0.0451	1
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0033	0.0022	0.8405
Echinococcus granulosus	7tm_1 domain containing protein	0.0053	0.0051	0.1318
Echinococcus granulosus	tm gpcr rhodopsin	0.0053	0.0051	0.1318
Echinococcus granulosus	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0053	0.0051	0.1318
Schistosoma mansoni	myosin xvIII	0.0053	0.0051	0.1318
Echinococcus multilocularis	neuropeptide Y receptor	0.0053	0.0051	0.1318
Brugia malayi	hypothetical protein	0.0033	0.0022	0.0494
Brugia malayi	G protein-coupled receptor	0.0053	0.0051	0.1135
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0053	0.0051	0.1318
Trypanosoma cruzi	hypothetical protein, conserved	0.0033	0.0022	0.8405
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0053	0.0051	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0051	0.0849
Entamoeba histolytica	translation initiation factor eIF-2B epsilon subunit, putative	0.0034	0.0024	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 797039