Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0146 | 0.0901 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Trypanosoma brucei | aldehyde dehydrogenase family, putative | 0.0081 | 0.0106 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0396 | 0.3983 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0146 | 0.0901 | 0.2262 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0073 | 0 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0081 | 0.0106 | 0.0266 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Echinococcus multilocularis | neuroligin | 0.0146 | 0.0901 | 0.2262 |
Echinococcus multilocularis | acetylcholinesterase | 0.0396 | 0.3983 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0146 | 0.0901 | 0.0901 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0396 | 0.3983 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0396 | 0.3983 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase (NAD+) dependent | 0.0081 | 0.0106 | 0.0106 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.0901 | 0.205 |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 0.3983 | 1 |
Onchocerca volvulus | 0.0146 | 0.0901 | 1 | |
Onchocerca volvulus | 0.0146 | 0.0901 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 0.3983 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.0901 | 0.205 |
Schistosoma mansoni | acetylcholinesterase | 0.0146 | 0.0901 | 0.2262 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Trypanosoma cruzi | aldehyde dehydrogenase family, putative | 0.0081 | 0.0106 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0146 | 0.0901 | 0.2262 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0146 | 0.0901 | 0.2262 |
Echinococcus granulosus | acetylcholinesterase | 0.0396 | 0.3983 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0073 | 0 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase family 3 member B1 | 0.0081 | 0.0106 | 0.0266 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0883 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0396 | 0.3983 | 1 |
Echinococcus multilocularis | Fatty aldehyde dehydrogenase | 0.0081 | 0.0106 | 0.0266 |
Echinococcus granulosus | aldehyde dehydrogenase family 3 member B1 | 0.0081 | 0.0106 | 0.0266 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Trypanosoma cruzi | aldehyde dehydrogenase family, putative | 0.0081 | 0.0106 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Entamoeba histolytica | aldehyde dehydrogenase 1, putative | 0.0081 | 0.0106 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0146 | 0.0901 | 0.0901 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0146 | 0.0901 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.0901 | 0.205 |
Echinococcus granulosus | carboxylesterase 5A | 0.0396 | 0.3983 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.0901 | 0.205 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0396 | 0.3983 | 1 |
Schistosoma mansoni | gliotactin | 0.0146 | 0.0901 | 0.2262 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0146 | 0.0901 | 0.2262 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Onchocerca volvulus | 0.0146 | 0.0901 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0396 | 0.3983 | 1 |
Onchocerca volvulus | 0.0146 | 0.0901 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Echinococcus granulosus | acetylcholinesterase | 0.0396 | 0.3983 | 1 |
Echinococcus granulosus | Fatty aldehyde dehydrogenase | 0.0081 | 0.0106 | 0.0266 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0146 | 0.0901 | 0.2262 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0146 | 0.0901 | 0.2262 |
Brugia malayi | Carboxylesterase family protein | 0.0396 | 0.3983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Mycobacterium ulcerans | aldehyde dehydrogenase (NAD+) dependent | 0.0081 | 0.0106 | 0.0106 |
Mycobacterium leprae | PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT | 0.0081 | 0.0106 | 0.5 |
Onchocerca volvulus | 0.0146 | 0.0901 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0146 | 0.0901 | 0.205 |
Loa Loa (eye worm) | carboxylesterase | 0.0146 | 0.0901 | 0.205 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0901 | 0.205 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.