Detailed information for compound 809992

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 379.436 | Formula: C19H17N5O2S
  • H donors: 1 H acceptors: 5 LogP: 2.07 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CSc1ncccn1)NCC1Cc2c(O1)c(ccc2)c1cncnc1
  • InChi: 1S/C19H17N5O2S/c25-17(11-27-19-22-5-2-6-23-19)24-10-15-7-13-3-1-4-16(18(13)26-15)14-8-20-12-21-9-14/h1-6,8-9,12,15H,7,10-11H2,(H,24,25)
  • InChiKey: LVOBBOFLAMOBAI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0421 0.1362 0.1296
Schistosoma mansoni tyrosine kinase 0.0065 0.0144 0.0597
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0068 0.0156 0.0081
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0194 0.0585 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0045 0.0075 0.0275
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0085 0.0295
Schistosoma mansoni tyrosine kinase 0.025 0.0778 0.3859
Echinococcus multilocularis Zinc finger, PHD finger 0.0068 0.0156 0.0656
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0085 0.0295
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0065 0.0144 0.0597
Brugia malayi intracellular kinase 0.0194 0.0585 0.371
Onchocerca volvulus 0.015 0.0434 0.7288
Schistosoma mansoni tyrosine kinase 0.0035 0.0041 0.0067
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0085 0.0334
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0065 0.0144 0.0597
Loa Loa (eye worm) SRC-1 0.0065 0.0144 0.0675
Onchocerca volvulus 0.0154 0.0448 0.7527
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0156 0.1574
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0085 0.0142
Echinococcus multilocularis tyrosine protein kinase Abl 0.0035 0.0041 0.0067
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0134 0.0382 0.6003
Schistosoma mansoni tyrosine kinase 0.0035 0.0041 0.0067
Schistosoma mansoni cell adhesion molecule 0.0044 0.0071 0.0221
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.0267 0.1591
Loa Loa (eye worm) hypothetical protein 0.0236 0.0728 0.4078
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0049 0.009 0.0317
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0085 0.001
Echinococcus multilocularis tyrosine protein kinase Srms 0.0061 0.0131 0.053
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0085 0.0199
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.0267 0.1393
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0134 0.0382 0.0309
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0082 0.0201 0.1755
Brugia malayi Immunoglobulin I-set domain containing protein 0.0198 0.06 0.3804
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0085 0.0295
Onchocerca volvulus 0.0142 0.0409 0.6828
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0065 0.0144 0.0597
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0068 0.0156 0.0081
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0065 0.0144 0.0597
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0134 0.0382 0.2802
Echinococcus granulosus neuroglian 0.0043 0.0069 0.0209
Loa Loa (eye worm) hypothetical protein 0.0044 0.0072 0.0256
Echinococcus granulosus c-Jun N-terminal kinases 0.0241 0.0747 0.37
Echinococcus multilocularis Immunoglobulin 0.0041 0.006 0.0165
Loa Loa (eye worm) TK protein kinase 0.0061 0.0131 0.06
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0075 0.0243
Onchocerca volvulus 0.0194 0.0585 1
Echinococcus multilocularis roundabout 2 0.0046 0.0079 0.0264
Echinococcus multilocularis protein kinase shaggy 0.0194 0.0585 0.2869
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0448 0.216
Trichomonas vaginalis hypothetical protein 0.2945 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0267 0.1231
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0041 0.006 0.0165
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0267 0.1492
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0421 0.1362 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Echinococcus granulosus tyrosine protein kinase HCK 0.0042 0.0066 0.0194
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0194 0.0585 0.2869
Plasmodium vivax protein kinase Crk2 0.0048 0.0085 0.0199
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0041 0.006 0.0165
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0085 0.0079
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0065 0.0144 0.0597
Brugia malayi Protein kinase domain containing protein 0.047 0.1531 1
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0085 0.0295
Brugia malayi Fibronectin type III domain containing protein 0.0041 0.006 0.0214
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0198 0.06 0.333
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0085 0.0199
Loa Loa (eye worm) phosphatidylinositol 3 0.0119 0.0328 0.1749
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0068 0.0156 0.1574
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0065 0.0144 0.0597
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0156 0.0081
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0236 0.0728 0.3603
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0156 0.1574
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0061 0.0131 0.053
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0134 0.0382 0.0309
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0085 0.0199
Echinococcus multilocularis tyrosine protein kinase shark 0.025 0.0778 0.3859
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0065 0.0144 0.0597
Loa Loa (eye worm) hypothetical protein 0.0045 0.0075 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Entamoeba histolytica protein kinase, putative 0.0194 0.0585 0.43
Echinococcus granulosus roundabout 2 0.0046 0.0079 0.0264
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0085 0.0142
Leishmania major phosphatidylinositol 3-kinase, putative 0.0068 0.0156 0.1574
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0068 0.0156 0.0656
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0131 0.053
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Echinococcus granulosus tyrosine protein kinase Lyn 0.0069 0.0157 0.0665
Loa Loa (eye worm) phosphatidylinositol 3 0.0533 0.1745 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0134 0.0382 0.2802
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0035 0.0041 0.0067
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0585 0.43
Brugia malayi protein-tyrosine kinase 0.0061 0.0131 0.0685
Brugia malayi Protein kinase domain containing protein 0.0048 0.0085 0.0382
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0045 0.0075 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0085 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0075 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0085 0.0295
Brugia malayi SRC-1 0.0065 0.0144 0.0771
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0068 0.0156 0.0656
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0085 0.0295
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.047 0.1531 0.8752
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0035 0.0041 0.0067
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0134 0.0382 0.2381
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0299
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0085 0.0079
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0194 0.0585 0.2869
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0075 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0747 0.37
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0068 0.0156 0.1142
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0068 0.0156 0.1142
Trypanosoma brucei polo-like protein kinase 0.0101 0.0267 0.376
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0254 0.0789 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.0267 0.4289
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0421 0.1362 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.0267 0.376
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0035 0.0041 0.0067
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0599 0.1971 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0041 0.006 0.0165
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0068 0.0156 0.0656
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Echinococcus multilocularis neuroglian 0.0043 0.0069 0.0209
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0085 0.0334
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0421 0.1362 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Echinococcus granulosus protein kinase shaggy 0.0194 0.0585 0.2869
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0085 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0599 0.1971 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0035 0.0041 0.0086
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0068 0.0156 0.0656
Echinococcus granulosus tyrosine kinase 0.0061 0.0131 0.053
Loa Loa (eye worm) AGC/PKA protein kinase 0.0045 0.0075 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Brugia malayi Stress-activated protein kinase jnk-1 0.0241 0.0747 0.4784
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0085 0.0295
Trypanosoma brucei protein kinase, putative 0.0194 0.0585 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0049 0.009 0.0317
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0031 0.0028 0.0206
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0585 0.43
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0236 0.0728 0.4659
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.032 0.1015 0.0947
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0267 0.0193
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0194 0.0585 0.2869
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0236 0.0728 0.3603
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0194 0.0585 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0267 0.1492
Echinococcus granulosus Immunoglobulin 0.0041 0.006 0.0165
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0085 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Echinococcus granulosus tyrosine protein kinase shark 0.025 0.0778 0.3859
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0599 0.1971 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Echinococcus granulosus tyrosine protein kinase Src64B 0.0065 0.0144 0.0597
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0421 0.1362 0.1296
Echinococcus multilocularis Immunoglobulin 0.0041 0.006 0.0165
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0085 0.0295
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0421 0.1362 0.8875
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.0267 0.1962
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0099 0.0024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0585 0.0514
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0134 0.0382 0.0309
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0299
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0085 0.0295
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0044 0.0071 0.0221
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0156 0.0624
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0085 0.0334
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0068 0.0156 0.0656
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.032 0.1015 0.0947
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0085 0.0627
Brugia malayi cell division control protein 2 homolog 0.0048 0.0085 0.0382
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0085 0.0079
Loa Loa (eye worm) hypothetical protein 0.0044 0.0071 0.025
Giardia lamblia Kinase, CMGC GSK 0.0194 0.0585 0.7148
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0041 0.0062 0.0174
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0075 0.0553
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0085 0.0199
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.0267 0.1231
Echinococcus multilocularis c src tyrosine kinase 0.0035 0.0041 0.0067
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.017 0.0502 0.3687
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0156 0.0624
Plasmodium vivax glycogen synthase kinase 3, putative 0.0194 0.0585 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0075 0.0553
Loa Loa (eye worm) hypothetical protein 0.0185 0.0555 0.3069
Plasmodium falciparum glycogen synthase kinase 3 0.0194 0.0585 1
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.006 0.0214
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0068 0.0156 0.0849
Schistosoma mansoni tyrosine kinase 0.0065 0.0144 0.0597
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0085 0.0627
Echinococcus granulosus tyrosine protein kinase Fyn 0.0065 0.0144 0.0597
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Echinococcus multilocularis tyrosine protein kinase Blk 0.0061 0.0131 0.053
Trichomonas vaginalis conserved hypothetical protein 0.2945 1 1
Schistosoma mansoni kinase 0.0053 0.0103 0.0386
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0194 0.0585 0.3247
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243
Echinococcus granulosus tyrosine protein kinase Src42A 0.0065 0.0144 0.0597
Entamoeba histolytica hypothetical protein 0.0355 0.1136 0.834
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0405 0.1308 0.9609
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0194 0.0585 0.3966
Onchocerca volvulus Tyrosine kinase homolog 0.0157 0.0458 0.7721
Echinococcus multilocularis tyrosine protein kinase HCK 0.0042 0.0066 0.0194
Schistosoma mansoni tyrosine kinase 0.0231 0.0712 0.3523
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0178 0.053 0.3344
Schistosoma mansoni vesicular amine transporter 0.0041 0.006 0.0165
Echinococcus granulosus tyrosine protein kinase Blk 0.0061 0.0131 0.053
Schistosoma mansoni nephrin 0.0043 0.0069 0.0209
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0421 0.1362 0.1296
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0085 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0585 0.0514
Echinococcus granulosus rho-associated protein kinase 1 0.0154 0.0448 0.216
Giardia lamblia Kinase, CMGC GSK 0.0194 0.0585 0.7148
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0355 0.1136 0.834
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0194 0.0585 0.3247
Echinococcus granulosus twitchin 0.0047 0.0082 0.0277
Plasmodium falciparum protein kinase 5 0.0048 0.0085 0.0199
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0134 0.0382 0.182
Giardia lamblia Kinase, PLK 0.0101 0.0267 0.2688
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0041 0.0062 0.0174
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0156 0.1574
Entamoeba histolytica protein kinase, putative 0.0042 0.0066 0.0482
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0119 0.0328 0.1967
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0241 0.0747 0.37
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0085 0.0199
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0156 0.1574
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0068 0.0156 0.0743
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.0267 0.1231
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0241 0.0747 0.4187
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0099 0.0024
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0068 0.0156 0.1574
Brugia malayi hypothetical protein 0.0041 0.006 0.0214
Echinococcus multilocularis rho associated protein kinase 0.0154 0.0448 0.216
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0187
Loa Loa (eye worm) TK protein kinase 0.0042 0.0066 0.0219
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0134 0.0382 0.2353
Echinococcus granulosus c src tyrosine kinase 0.0035 0.0041 0.0067
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0065 0.0144 0.0597
Echinococcus granulosus defective proboscis extension response 0.0041 0.006 0.0165
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0045 0.0075 0.0243

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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