Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0425 | 0.0966 |
Onchocerca volvulus | 0.0282 | 0.1141 | 0.5133 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Loa Loa (eye worm) | hypothetical protein | 0.0602 | 0.3656 | 0.4046 |
Brugia malayi | Trehalase family protein | 0.0282 | 0.1141 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1141 | 0.0946 |
Trypanosoma cruzi | glycosyl hydrolase, putative | 0.0137 | 0 | 0.5 |
Loa Loa (eye worm) | TRE-2 protein | 0.0282 | 0.1141 | 0.0946 |
Trypanosoma brucei | glycosyl hydrolase, putative | 0.0137 | 0 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0562 | 0.334 | 0.3657 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1141 | 0.0946 |
Loa Loa (eye worm) | trehalase | 0.0282 | 0.1141 | 0.0946 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1141 | 0.0946 |
Plasmodium vivax | hypothetical protein, conserved | 0.0184 | 0.0371 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Brugia malayi | Trehalase family protein | 0.0282 | 0.1141 | 0.0053 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0184 | 0.0371 | 0.5 |
Onchocerca volvulus | 0.0282 | 0.1141 | 0.5133 | |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0562 | 0.334 | 0.2522 |
Leishmania major | glycosyl hydrolase, putative | 0.0137 | 0 | 0.5 |
Onchocerca volvulus | 0.0282 | 0.1141 | 0.5133 | |
Echinococcus multilocularis | beta galactosidase | 0.0602 | 0.3656 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0425 | 0.0966 |
Echinococcus granulosus | beta galactosidase | 0.0602 | 0.3656 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Brugia malayi | hypothetical protein | 0.0282 | 0.1141 | 0.0053 |
Schistosoma mansoni | beta-galactosidase | 0.0602 | 0.3656 | 1 |
Onchocerca volvulus | 0.0282 | 0.1141 | 0.5133 | |
Brugia malayi | Trehalase family protein | 0.0282 | 0.1141 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1141 | 0.0946 |
Loa Loa (eye worm) | trehalase | 0.0282 | 0.1141 | 0.0946 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0276 | 0.1094 | 0.0888 |
Onchocerca volvulus | Trehalase homolog | 0.0282 | 0.1141 | 0.5133 |
Onchocerca volvulus | 0.0282 | 0.1141 | 0.5133 | |
Loa Loa (eye worm) | hypothetical protein | 0.1217 | 0.8486 | 1 |
Mycobacterium leprae | Possible hydrolase | 0.0137 | 0 | 0.5 |
Mycobacterium ulcerans | glycosyl hydrolase | 0.0137 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1141 | 0.0946 |
Mycobacterium tuberculosis | Conserved protein | 0.0137 | 0 | 0.5 |
Loa Loa (eye worm) | TRE-1 protein | 0.0282 | 0.1141 | 0.0946 |
Trichomonas vaginalis | trehalase, putative | 0.0282 | 0.1141 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0282 | 0.1141 | 1 |
Brugia malayi | Trehalase family protein | 0.0282 | 0.1141 | 0.0053 |
Loa Loa (eye worm) | trehalase | 0.0282 | 0.1141 | 0.0946 |
Onchocerca volvulus | 0.0377 | 0.1892 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0276 | 0.1094 | 0.9407 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.