Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0076 | 1 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0059 | 0.7224 | 0.7224 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0059 | 0.7224 | 0.7224 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0076 | 1 | 1 |
Onchocerca volvulus | Notchless protein homolog | 0.0015 | 0 | 0.5 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0059 | 0.7224 | 0.7224 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0059 | 0.7224 | 0.7224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0036 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0076 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0036 | 0.3546 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0036 | 0.3546 | 0.3546 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0059 | 0.7224 | 0.7224 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0076 | 1 | 1 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0036 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0036 | 0.3546 | 0.3546 |
Brugia malayi | proteasome subunit beta type 1 | 0.0059 | 0.7224 | 0.7224 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0076 | 1 | 1 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0036 | 0.3546 | 0.3546 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0036 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0036 | 0.3546 | 0.3546 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0015 | 0 | 0.5 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0036 | 0.3546 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0076 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 2 | 0.0036 | 0.3546 | 0.3546 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0076 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0059 | 0.7224 | 0.7224 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0036 | 0.3546 | 0.3546 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0076 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0036 | 0.3546 | 0.3546 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0076 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0059 | 0.7224 | 0.7224 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0076 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0076 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0059 | 0.7224 | 0.7224 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0076 | 1 | 1 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0059 | 0.7224 | 0.7224 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0059 | 0.7224 | 0.7224 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0076 | 1 | 1 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0036 | 0.3546 | 0.3546 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0076 | 1 | 1 |
Mycobacterium ulcerans | proteasome PrcB | 0.0076 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0036 | 0.3546 | 0.3546 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0059 | 0.7224 | 0.7224 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0036 | 0.3546 | 0.3546 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0036 | 0.3546 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0059 | 0.7224 | 0.7224 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0059 | 0.7224 | 0.7224 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0036 | 0.3546 | 0.3546 |
Echinococcus granulosus | proteasome prosome macropain | 0.0076 | 1 | 1 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0059 | 0.7224 | 0.7224 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.