Detailed information for compound 829573

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 380.397 | Formula: C20H20N4O4
  • H donors: 1 H acceptors: 2 LogP: 2.15 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1nn(CC(=O)NCc2ccc(cc2)OC)c(=O)c2n1c1ccoc1c2
  • InChi: 1S/C20H20N4O4/c1-3-18-22-23(20(26)16-10-17-15(24(16)18)8-9-28-17)12-19(25)21-11-13-4-6-14(27-2)7-5-13/h4-10H,3,11-12H2,1-2H3,(H,21,25)
  • InChiKey: QAVHXIUTALSCBF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hexose transporter 0.0067 0.0554 0.8107
Schistosoma mansoni sugar transporter 0.0031 0.0147 0.0666
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.018 0.0274
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0346 0.1563
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0081
Loa Loa (eye worm) pyruvate kinase 0.0034 0.018 0.0695
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.018 0.0662
Schistosoma mansoni sugar transporter 0.0031 0.0147 0.0666
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0423 0.1187
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Toxoplasma gondii facilitative glucose transporter GT1 0.0217 0.2211 0.3353
Trichomonas vaginalis glucose transporter, putative 0.0067 0.0554 0.1973
Schistosoma mansoni sugar transporter 0.0031 0.0147 0.0666
Echinococcus multilocularis solute carrier family 22 0.0031 0.0147 0.0413
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0067 0.0545 0.1528
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0029 0.0081
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0081
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0147 0.2954
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.0346 0.395
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0068 0.0181
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0346 1
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0346 0.1452
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0649 1
Echinococcus granulosus solute carrier family 22 0.0031 0.0147 0.0413
Schistosoma mansoni polycystin 1-related 0.002 0.0029 0.013
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0147 0.0543
Onchocerca volvulus 0.0031 0.0147 0.3582
Onchocerca volvulus 0.0031 0.0147 0.3582
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.0346 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.0545 0.0545
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0554 0.8107
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0147 0.0147
Schistosoma mansoni protein kinase 0.0067 0.0545 0.2465
Onchocerca volvulus 0.005 0.0359 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.018 0.0662
Echinococcus granulosus solute carrier family 22 0.0031 0.0147 0.0413
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.018 0.2827
Onchocerca volvulus 0.0031 0.0147 0.3582
Loa Loa (eye worm) hypothetical protein 0.0065 0.053 0.2297
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0554 0.1973
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0554 0.8107
Mycobacterium ulcerans pyruvate kinase 0.0034 0.018 0.4135
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0554 0.1973
Giardia lamblia Pyruvate kinase 0.0034 0.018 0.3406
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0064 0.5
Echinococcus multilocularis pyruvate kinase 0.0034 0.018 0.0506
Schistosoma mansoni protein kinase 0.0067 0.0545 0.2465
Schistosoma mansoni lipoxygenase 0.002 0.0029 0.013
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0029 0.0029
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0065 0.053 1
Onchocerca volvulus 0.0031 0.0147 0.3582
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.0346 0.0524
Brugia malayi lysyl-tRNA synthetase 0.0049 0.0346 0.1452
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0147 0.0413
Giardia lamblia Prolyl-tRNA synthetase 0.0065 0.053 1
Echinococcus multilocularis pyruvate kinase 0.0026 0.0102 0.0287
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0346 0.1563
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0265 0.2412
Echinococcus granulosus calcium dependent protein kinase 0.0062 0.0499 0.14
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0065 0.053 0.2297
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0067 0.0545 0.7919
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0147 0.2954
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0147 0.0543
Onchocerca volvulus 0.0031 0.0147 0.3582
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.0545 0.0545
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.0346 0.395
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0265 1
Plasmodium vivax hexose transporter 0.0217 0.2211 0.2211
Echinococcus multilocularis pyruvate kinase 0.0034 0.018 0.0506
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0181
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.053 0.2397
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Leishmania major protein kinase, putative 0.0067 0.0545 0.7919
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Loa Loa (eye worm) hypothetical protein 0.005 0.0359 0.1515
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Brugia malayi Sugar transporter family protein 0.0031 0.0147 0.0543
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.018 0.4587
Plasmodium vivax pyruvate kinase, putative 0.0034 0.018 0.018
Toxoplasma gondii sugar transporter ST3 0.0031 0.0147 0.0223
Leishmania major glucose transporter/membrane transporter D2, putative 0.0067 0.0554 0.8107
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0081
Trichomonas vaginalis glucose transporter, putative 0.0067 0.0554 0.1973
Onchocerca volvulus 0.0031 0.0147 0.3582
Plasmodium falciparum hexose transporter 0.0217 0.2211 0.2211
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0554 0.1973
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0029 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0545 0.1927
Trypanosoma brucei glucose transporter 2A 0.0067 0.0554 0.8107
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0554 0.1973
Echinococcus multilocularis tumor protein p63 0.034 0.3566 1
Toxoplasma gondii protein kinase, putative 0.0614 0.6593 1
Onchocerca volvulus 0.0031 0.0147 0.3582
Echinococcus multilocularis solute carrier family 22 0.0031 0.0147 0.0413
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0065 0.053 0.1486
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Entamoeba histolytica protein kinase, putative 0.0067 0.0545 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0105 0.0351
Plasmodium vivax sugar transporter, putative 0.0031 0.0147 0.0147
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0649 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.028 0.0641
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0147 0.0413
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0029 0.0029
Brugia malayi hypothetical protein 0.0031 0.0147 0.0543
Brugia malayi hypothetical protein 0.0031 0.0147 0.0543
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0217 0.1383
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0147 0.0223
Plasmodium falciparum proline--tRNA ligase 0.0076 0.0649 0.0649
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0554 0.8107
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.0545 0.0545
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.053 0.2397
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0554 0.8107
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0065 0.053 0.1855
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0649 1
Entamoeba histolytica protein kinase, putative 0.0067 0.0545 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0065 0.053 0.2297
Leishmania major glucose transporter, lmgt3 0.0067 0.0554 0.8107
Loa Loa (eye worm) hypothetical protein 0.0053 0.0395 0.1678
Echinococcus multilocularis solute carrier family 22 0.0031 0.0147 0.0413
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.013
Loa Loa (eye worm) hypothetical protein 0.0065 0.053 0.2297
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.0545 0.0827
Echinococcus granulosus tumor protein p63 0.034 0.3566 1
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0359 0.1626
Trypanosoma brucei glucose transporter 1E 0.0067 0.0554 0.8107
Trypanosoma brucei pyruvate kinase 1 0.0034 0.018 0.0662
Schistosoma mansoni glucose transport protein 0.0217 0.2211 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Brugia malayi Sugar transporter family protein 0.0031 0.0147 0.0543
Mycobacterium ulcerans sugar transporter 0.0031 0.0147 0.2954
Schistosoma mansoni loxhd1 0.002 0.0029 0.013
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0346 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0065 0.053 0.9688
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0217 0.2211 0.6199
Brugia malayi major facilitator superfamily protein 0.0031 0.0147 0.0543
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.018 0.0695
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Schistosoma mansoni protein kinase 0.0067 0.0545 0.2465
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0554 0.8107
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Plasmodium falciparum mitogen-activated protein kinase 2 0.0351 0.3689 0.3689
Schistosoma mansoni sugar transporter 0.0031 0.0147 0.0666
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.018 0.0161
Giardia lamblia Sugar-proton symporter 0.0031 0.0147 0.2779
Schistosoma mansoni glucose transporter 0.0031 0.0147 0.0666
Echinococcus multilocularis solute carrier family 22 0.0031 0.0147 0.0413
Loa Loa (eye worm) pyruvate kinase 0.0034 0.018 0.0695
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.018 0.4587
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0065 0.053 0.1486
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.0346 0.0961
Schistosoma mansoni hypothetical protein 0.0217 0.2211 1
Echinococcus granulosus solute carrier family 22 0.0031 0.0147 0.0413
Echinococcus granulosus RUN 0.002 0.0029 0.0081
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0147 0.0543
Echinococcus multilocularis RUN 0.002 0.0029 0.0081
Loa Loa (eye worm) sugar transporter 0.0031 0.0147 0.0543
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2211 0.6199
Onchocerca volvulus 0.0031 0.0147 0.3582
Brugia malayi hypothetical protein 0.0031 0.0147 0.0543
Brugia malayi Sugar transporter family protein 0.0217 0.2211 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Plasmodium vivax CDK-related protein kinase 6, putative 0.0922 1 1
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0147 0.2954
Giardia lamblia Hexose transporter 0.0031 0.0147 0.2779
Onchocerca volvulus 0.0031 0.0147 0.3582
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0649 1
Brugia malayi Cam kinase protein 1 0.0067 0.0545 0.2365
Entamoeba histolytica hypothetical protein 0.0049 0.0346 0.5818
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.018 0.0695
Onchocerca volvulus 0.0031 0.0147 0.3582
Echinococcus granulosus solute carrier family 22 0.0031 0.0147 0.0413
Schistosoma mansoni lipoxygenase 0.0056 0.0423 0.1915
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0147 0.0543
Onchocerca volvulus 0.0031 0.0147 0.3582
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0423 0.1187
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0265 1
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Loa Loa (eye worm) hypothetical protein 0.0034 0.018 0.0695
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0554 0.8107
Onchocerca volvulus 0.0031 0.0147 0.3582
Onchocerca volvulus 0.0031 0.0147 0.3582
Schistosoma mansoni pyruvate kinase 0.0034 0.018 0.0816
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.0545 0.0545
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.0346 0.0969
Echinococcus granulosus General substrate transporter 0.0187 0.1873 0.5253
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0147 0.5
Echinococcus granulosus pyruvate kinase 0.0034 0.018 0.0506
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Onchocerca volvulus 0.0031 0.0147 0.3582
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.0545 0.0545
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Echinococcus multilocularis General substrate transporter 0.0187 0.1873 0.5253
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.0545 0.0827
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.0545 0.0545
Echinococcus multilocularis calcium dependent protein kinase 0.0062 0.0499 0.14
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0147 0.0543
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0067 0.0545 0.2365
Leishmania major glucose transporter, lmgt1 0.0067 0.0554 0.8107
Leishmania major pyruvate kinase 0.0034 0.018 0.0662
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0067 0.0545 0.2365
Plasmodium falciparum protein kinase 7 0.0614 0.6593 0.6593
Onchocerca volvulus 0.0031 0.0147 0.3582
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.018 0.0662
Loa Loa (eye worm) hypothetical protein 0.0031 0.0147 0.0543
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0554 0.1973
Loa Loa (eye worm) sugar transporter 0.0217 0.2211 1
Brugia malayi major facilitator superfamily protein 0.0031 0.0147 0.0543
Schistosoma mansoni glucose transport protein 0.0217 0.2211 1
Echinococcus granulosus pyruvate kinase 0.0034 0.018 0.0506
Loa Loa (eye worm) pyruvate kinase 0.0034 0.018 0.0695
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0147 0.0413
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0067 0.0545 0.2365
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0351 0.3689 0.3689
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0076 0.0649 0.0985
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.0545 0.0545
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0147 0.0666
Onchocerca volvulus 0.0031 0.0147 0.3582
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.2211 1
Chlamydia trachomatis pyruvate kinase 0.0034 0.018 0.4135
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.0346 0.0969
Onchocerca volvulus Putative transporter 0.0031 0.0147 0.3582
Schistosoma mansoni pyruvate kinase 0.0034 0.018 0.0816
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.0346 0.0346
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0649 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0081
Loa Loa (eye worm) hypothetical protein 0.0067 0.0545 0.2365
Plasmodium falciparum pyruvate kinase 0.0034 0.018 0.018
Toxoplasma gondii sugar transporter ST2 0.0031 0.0147 0.0223
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.018 0.4587
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.0545 0.0545
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.0346 0.4724
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0545 0.2465
Plasmodium vivax proline--tRNA ligase, putative 0.0076 0.0649 0.0649
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.0346 0.6521
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.0346 0.0346
Leishmania major glucose transporter, lmgt2 0.0067 0.0554 0.8107
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0147 0.0413
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.018 0.0161
Schistosoma mansoni glucose transport protein 0.0217 0.2211 1
Toxoplasma gondii sugar transporter ST1 0.0031 0.0147 0.0223
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.0545 0.0827
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.0545 0.0545
Trypanosoma brucei glucose transporter, putative 0.0067 0.0554 0.8107
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0351 0.3689 0.5596
Leishmania major pyruvate kinase 0.0034 0.018 0.0662
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0545 0.1528
Schistosoma mansoni hypothetical protein 0.002 0.0029 0.013
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.0346 0.395

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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