Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Loa Loa (eye worm) | cathepsin B | 0.0425 | 0.3161 | 0.3093 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Leishmania major | cysteine peptidase A (CPA) | 0.0258 | 0.1608 | 0.5087 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0719 | 0.0627 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0258 | 0.1608 | 0.1524 |
Plasmodium vivax | vivapain-2 | 0.0258 | 0.1608 | 1 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0095 | 0.0099 | 0.0613 |
Onchocerca volvulus | Proteasomal ubiquitin receptor ADRM1 homolog | 0.0103 | 0.0171 | 0.0481 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0425 | 0.3161 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0258 | 0.1608 | 0.1524 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0425 | 0.3161 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Echinococcus multilocularis | adhesion regulating molecule 1 | 0.0162 | 0.0719 | 0.0627 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0258 | 0.1608 | 1 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0258 | 0.1608 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.1608 | 0.1524 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3161 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0258 | 0.1608 | 1 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.1608 | 0.1524 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0258 | 0.1608 | 0.1524 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1163 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0095 | 0.0099 | 0.0613 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Echinococcus multilocularis | cathepsin b | 0.1163 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0258 | 0.1608 | 0.1524 |
Brugia malayi | Adhesion regulating molecule conserved region family protein | 0.0162 | 0.0719 | 0.0627 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0095 | 0.0099 | 0.0613 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Toxoplasma gondii | cathepsin CPL | 0.0258 | 0.1608 | 0.4929 |
Echinococcus granulosus | cathepsin b | 0.1163 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Onchocerca volvulus | Cathepsin F homolog | 0.0258 | 0.1608 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1163 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1163 | 1 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0095 | 0.0099 | 0.0613 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0258 | 0.1608 | 0.1524 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.1608 | 0.1524 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0425 | 0.3161 | 0.3093 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0095 | 0.0099 | 0.0613 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0258 | 0.1608 | 0.1524 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0095 | 0.0099 | 0.0613 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Plasmodium vivax | vivapain-2 | 0.0258 | 0.1608 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1163 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.1608 | 0.1524 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0258 | 0.1608 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0258 | 0.1608 | 0.1524 |
Brugia malayi | cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0258 | 0.1608 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0258 | 0.1608 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Onchocerca volvulus | Cathepsin L homolog | 0.0258 | 0.1608 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0258 | 0.1608 | 0.1524 |
Loa Loa (eye worm) | cysteine protease | 0.0258 | 0.1608 | 0.1524 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.1608 | 0.1524 |
Schistosoma mansoni | adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) | 0.0162 | 0.0719 | 0.0627 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0425 | 0.3161 | 1 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Echinococcus granulosus | adhesion regulating molecule 1 | 0.0162 | 0.0719 | 0.0627 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Entamoeba histolytica | cysteine protease, putative | 0.0258 | 0.1608 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.1608 | 0.1524 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 | |
Toxoplasma gondii | cathepsin B | 0.0425 | 0.3161 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0258 | 0.1608 | 0.1524 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0258 | 0.1608 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Echinococcus granulosus | cathepsin b | 0.1163 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1163 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0095 | 0.0099 | 0.0613 |
Loa Loa (eye worm) | fibroinase | 0.0258 | 0.1608 | 0.1524 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0425 | 0.3161 | 0.3093 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.1608 | 0.1524 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3161 | 1 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0095 | 0.0099 | 0.0613 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Toxoplasma gondii | adhesion regulating molecule region protein, putative | 0.0162 | 0.0719 | 0.2027 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0095 | 0.0099 | 0.0613 |
Echinococcus multilocularis | cysteine protease | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.1608 | 0.4929 |
Echinococcus granulosus | cathepsin l1 | 0.0258 | 0.1608 | 0.1524 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0095 | 0.0099 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.1163 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1163 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0095 | 0.0099 | 0.0613 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3161 | 1 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0095 | 0.0099 | 0.0613 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.1608 | 0.1524 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0095 | 0.0099 | 0.0613 |
Loa Loa (eye worm) | ctsf protein | 0.0258 | 0.1608 | 0.1524 |
Brugia malayi | Cathepsin L-like precursor | 0.0258 | 0.1608 | 0.1524 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Echinococcus multilocularis | cysteine protease | 0.0258 | 0.1608 | 0.1524 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0258 | 0.1608 | 0.4929 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0258 | 0.1608 | 0.1524 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.1608 | 0.5087 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0258 | 0.1608 | 0.1524 |
Onchocerca volvulus | 0.0258 | 0.1608 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.