Detailed information for compound 831145

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 409.477 | Formula: C22H20FN3O2S
  • H donors: 2 H acceptors: 4 LogP: 4.28 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1Nc2nc(SCc3ccc(cc3)F)nc(c2C(C1)c1ccc(cc1C)C)O
  • InChi: 1S/C22H20FN3O2S/c1-12-3-8-16(13(2)9-12)17-10-18(27)24-20-19(17)21(28)26-22(25-20)29-11-14-4-6-15(23)7-5-14/h3-9,17H,10-11H2,1-2H3,(H2,24,25,26,27,28)
  • InChiKey: HPZPKSUGBJSMGL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.003 0.0144 0.3404
Plasmodium vivax hexose transporter 0.021 0.2208 0.2208
Trypanosoma brucei glucose transporter 2A 0.0065 0.0551 0.8107
Onchocerca volvulus 0.003 0.0144 0.3404
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0646 1
Giardia lamblia Hexose transporter 0.003 0.0144 0.2732
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0144 0.2954
Plasmodium vivax CDK-related protein kinase 6, putative 0.0893 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Brugia malayi hypothetical protein 0.003 0.0144 0.0526
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0527 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0342 0.0943
Loa Loa (eye worm) sugar transporter 0.003 0.0144 0.0526
Echinococcus multilocularis RUN 0.002 0.0029 0.0081
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0144 0.0526
Echinococcus granulosus solute carrier family 22 0.003 0.0144 0.0397
Echinococcus granulosus RUN 0.002 0.0029 0.0081
Schistosoma mansoni glucose transport protein 0.021 0.2208 1
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0184 0.0193
Schistosoma mansoni sugar transporter 0.003 0.0144 0.0652
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.034 0.3687 0.3687
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0184 0.4587
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0184 0.0709
Echinococcus multilocularis solute carrier family 22 0.003 0.0144 0.0397
Schistosoma mansoni glucose transporter 0.003 0.0144 0.0652
Giardia lamblia Sugar-proton symporter 0.003 0.0144 0.2732
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Brugia malayi major facilitator superfamily protein 0.003 0.0144 0.0526
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0551 0.8107
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0184 0.0709
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0542 0.0542
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0496 0.1367
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0542 0.7919
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0144 0.0526
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0542 0.0542
Echinococcus granulosus General substrate transporter 0.0181 0.187 0.5152
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0342 0.0943
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Echinococcus multilocularis General substrate transporter 0.0181 0.187 0.5152
Onchocerca volvulus 0.003 0.0144 0.3404
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0542 0.0542
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0144 0.5
Echinococcus granulosus pyruvate kinase 0.0033 0.0184 0.0506
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0542 0.2352
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0262 1
Onchocerca volvulus 0.003 0.0144 0.3404
Schistosoma mansoni lipoxygenase 0.0055 0.0431 0.1952
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0144 0.0526
Onchocerca volvulus 0.003 0.0144 0.3404
Schistosoma mansoni pyruvate kinase 0.0033 0.0184 0.0832
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Onchocerca volvulus 0.003 0.0144 0.3404
Leishmania major glucose transporter, lmgt2 0.0065 0.0551 0.8107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0184 0.0709
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Echinococcus granulosus solute carrier family 22 0.003 0.0144 0.0397
Onchocerca volvulus 0.003 0.0144 0.3404
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0184 0.0709
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0342 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0542 0.0542
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0542 0.0822
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0431 0.1187
Chlamydia trachomatis pyruvate kinase 0.0033 0.0184 0.4368
Onchocerca volvulus 0.003 0.0144 0.3404
Toxoplasma gondii facilitative glucose transporter GT1 0.021 0.2208 0.3349
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0144 0.0652
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0342 0.0342
Schistosoma mansoni pyruvate kinase 0.0033 0.0184 0.0832
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0342 0.6498
Onchocerca volvulus Putative transporter 0.003 0.0144 0.3404
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0184 0.0709
Echinococcus granulosus pyruvate kinase 0.0033 0.0184 0.0506
Schistosoma mansoni glucose transport protein 0.021 0.2208 1
Schistosoma mansoni glucose transport protein 0.021 0.2208 1
Brugia malayi major facilitator superfamily protein 0.003 0.0144 0.0526
Plasmodium vivax proline--tRNA ligase, putative 0.0074 0.0646 0.0646
Entamoeba histolytica protein kinase, putative 0.0064 0.0542 1
Plasmodium falciparum mitogen-activated protein kinase 2 0.034 0.3687 0.3687
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0542 0.0822
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0144 0.0397
Plasmodium falciparum protein kinase 7 0.0594 0.6592 0.6592
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0542 0.2352
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0551 0.1973
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0184 0.0793
Onchocerca volvulus 0.003 0.0144 0.3404
Leishmania major pyruvate kinase 0.0033 0.0184 0.0793
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0542 0.0542
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.034 0.3687 0.5593
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0542 0.0542
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0551 0.8107
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0551 0.1973
Toxoplasma gondii sugar transporter ST1 0.003 0.0144 0.0218
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0342 0.395
Schistosoma mansoni hypothetical protein 0.002 0.0029 0.0133
Schistosoma mansoni protein kinase 0.0064 0.0542 0.2453
Leishmania major pyruvate kinase 0.0033 0.0184 0.0793
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0144 0.0397
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0542 0.2453
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0184 0.0193
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0646 1
Trypanosoma brucei glucose transporter 1E 0.0065 0.0551 0.8107
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0342 0.4623
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0551 0.1973
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0047 0.0342 0.1437
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0542 0.0822
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0081
Plasmodium falciparum proline--tRNA ligase 0.0074 0.0646 0.0646
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0184 0.4587
Toxoplasma gondii sugar transporter ST2 0.003 0.0144 0.0218
Plasmodium falciparum pyruvate kinase 0.0033 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0342 1
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0551 0.1973
Onchocerca volvulus 0.003 0.0144 0.3404
Onchocerca volvulus 0.003 0.0144 0.3404
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0144 0.0526
Onchocerca volvulus 0.0049 0.0366 1
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0551 0.8107
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0144 0.0144
Schistosoma mansoni protein kinase 0.0064 0.0542 0.2453
Entamoeba histolytica hypothetical protein 0.0047 0.0342 0.5778
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.0133
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0342 0.0961
Schistosoma mansoni polycystin 1-related 0.002 0.0029 0.0133
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0074 0.0646 0.098
Echinococcus granulosus solute carrier family 22 0.003 0.0144 0.0397
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Echinococcus multilocularis solute carrier family 22 0.003 0.0144 0.0397
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Schistosoma mansoni sugar transporter 0.003 0.0144 0.0652
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.007 0.0184
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0342 0.395
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0144 0.2954
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0551 0.8107
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0081
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0029 0.0081
Schistosoma mansoni sugar transporter 0.003 0.0144 0.0652
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0184 0.0709
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0184 0.0793
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0081
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0342 0.155
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0184 0.0279
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Schistosoma mansoni sugar transporter 0.003 0.0144 0.0652
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.021 0.2208 0.6082
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0431 0.1187
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0262 0.2267
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0496 0.1367
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0542 0.0542
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0144 0.2954
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0527 0.2283
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0342 1
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0342 0.1437
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0342 0.155
Echinococcus multilocularis pyruvate kinase 0.0026 0.0104 0.0287
Loa Loa (eye worm) hypothetical protein 0.0063 0.0527 0.2283
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0144 0.0397
Schistosoma mansoni lipoxygenase 0.002 0.0029 0.0133
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Echinococcus multilocularis pyruvate kinase 0.0033 0.0184 0.0506
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0061 0.5
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0551 0.8107
Giardia lamblia Pyruvate kinase 0.0033 0.0184 0.3488
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Onchocerca volvulus 0.003 0.0144 0.3404
Loa Loa (eye worm) hypothetical protein 0.0063 0.0527 0.2283
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0029 0.0029
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0527 0.1855
Onchocerca volvulus 0.003 0.0144 0.3404
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0184 0.0793
Echinococcus granulosus solute carrier family 22 0.003 0.0144 0.0397
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0184 0.3385
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0184 0.4368
Loa Loa (eye worm) hypothetical protein 0.0064 0.0542 0.2352
Schistosoma mansoni hypothetical protein 0.021 0.2208 1
Brugia malayi Cam kinase protein 1 0.0064 0.0542 0.2352
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0102 0.0333
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Brugia malayi Sugar transporter family protein 0.021 0.2208 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0527 0.9685
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0029 0.0029
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0144 0.0397
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0276 0.0641
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0074 0.0646 1
Plasmodium vivax sugar transporter, putative 0.003 0.0144 0.0144
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0029 0.0081
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0551 0.1973
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Trichomonas vaginalis conserved hypothetical protein 0.021 0.2208 1
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0551 0.1973
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0081
Onchocerca volvulus 0.003 0.0144 0.3404
Echinococcus multilocularis solute carrier family 22 0.003 0.0144 0.0397
Onchocerca volvulus 0.003 0.0144 0.3404
Echinococcus granulosus tumor protein p63 0.0335 0.363 1
Toxoplasma gondii protein kinase, putative 0.0594 0.6592 1
Trypanosoma brucei glucose transporter, putative 0.0065 0.0551 0.8107
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0551 0.1973
Leishmania major glucose transporter, lmgt3 0.0065 0.0551 0.8107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0542 0.1492
Entamoeba histolytica protein kinase, putative 0.0064 0.0542 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0542 0.1927
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0184 0.0184
Toxoplasma gondii sugar transporter ST3 0.003 0.0144 0.0218
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0184 0.4587
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Brugia malayi Sugar transporter family protein 0.003 0.0144 0.0526
Loa Loa (eye worm) hypothetical protein 0.0049 0.0366 0.1545
Loa Loa (eye worm) sugar transporter 0.021 0.2208 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0262 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0342 0.395
Schistosoma mansoni protein kinase 0.0064 0.0542 0.2453
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0144 0.0526
Onchocerca volvulus 0.003 0.0144 0.3404
Trypanosoma cruzi hexose transporter 0.0065 0.0551 0.8107
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0527 0.1451
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0184
Echinococcus multilocularis pyruvate kinase 0.0033 0.0184 0.0506
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Plasmodium falciparum hexose transporter 0.021 0.2208 0.2208
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0184 0.0793
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0551 0.8107
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0366 0.1657
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0527 1
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0342 0.0519
Schistosoma mansoni loxhd1 0.002 0.0029 0.0133
Mycobacterium ulcerans sugar transporter 0.003 0.0144 0.2954
Brugia malayi Sugar transporter family protein 0.003 0.0144 0.0526
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0526
Echinococcus multilocularis solute carrier family 22 0.003 0.0144 0.0397
Echinococcus multilocularis tumor protein p63 0.0335 0.363 1
Leishmania major glucose transporter, lmgt1 0.0065 0.0551 0.8107
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0527 0.2386
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.0133
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0527 0.2283
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0542 0.0542
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0527 0.2386
Loa Loa (eye worm) hypothetical protein 0.0051 0.0392 0.1663
Leishmania major protein kinase, putative 0.0064 0.0542 0.7919
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0527 0.1451
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0551 0.8107
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0646 1
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0144 0.0218
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0074 0.0646 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0213 0.1383
Brugia malayi hypothetical protein 0.003 0.0144 0.0526
Brugia malayi hypothetical protein 0.003 0.0144 0.0526
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0542 0.1492
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2208 0.6082
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0542 0.2352
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0542 0.0542

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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