Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.4455 | 0.7578 | 0.5 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.4455 | 0.7578 | 0.5 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.1722 | 0 | 0.5 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.3719 | 0.5536 | 0.5536 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.4455 | 0.7578 | 0.5 |
Treponema pallidum | uridine phosphorylase (udp) | 0.4455 | 0.7578 | 0.5 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.5329 | 1 | 0.5 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.1722 | 0 | 0.5 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.5329 | 1 | 0.5 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.5329 | 1 | 0.5 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.4455 | 0.7578 | 0.5 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.3719 | 0.5536 | 0.5536 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.4455 | 0.7578 | 0.5 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3719 | 0.5536 | 1 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.4455 | 0.7578 | 0.5 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.1722 | 0 | 0.5 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.3719 | 0.5536 | 0.5536 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.5329 | 1 | 0.5 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.5329 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.1722 | 0 | 0.5 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.5329 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.