Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0032 | 0.0106 | 0.0542 | |
Brugia malayi | Pre-SET motif family protein | 0.0023 | 0.0042 | 0.0072 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0802 | 0.5785 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0252 | 0.1727 | 0.2985 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Giardia lamblia | DINP protein human, muc B family | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0106 | 0.0183 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0032 | 0.0106 | 0.0183 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0032 | 0.0106 | 0.0183 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0802 | 0.5785 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0106 | 0.0183 |
Brugia malayi | Pre-SET motif family protein | 0.0162 | 0.1065 | 0.1841 |
Brugia malayi | Adenosylhomocysteinase | 0.0802 | 0.5785 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0032 | 0.0106 | 0.0183 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0802 | 0.5785 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0802 | 0.5785 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0106 | 0.0183 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0802 | 0.5785 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0032 | 0.0106 | 0.0112 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0802 | 0.5785 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0802 | 0.5785 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0106 | 0.0183 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0032 | 0.0106 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.0042 | 0.0072 |
Mycobacterium ulcerans | beta-lactamase | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0204 | 0.1376 | 0.2379 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0802 | 0.5785 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0802 | 0.5785 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0032 | 0.0106 | 0.0183 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0802 | 0.5785 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.0042 | 0.0072 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0802 | 0.5785 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0162 | 0.1065 | 0.1841 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0023 | 0.0042 | 0.0072 |
Onchocerca volvulus | 0.0032 | 0.0106 | 0.0542 | |
Onchocerca volvulus | 0.0032 | 0.0106 | 0.0542 | |
Brugia malayi | beta-lactamase | 0.0032 | 0.0106 | 0.0183 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0497 | 0.353 | 0.6103 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0497 | 0.353 | 0.6103 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0032 | 0.0106 | 0.0183 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0497 | 0.353 | 0.6103 |
Onchocerca volvulus | 0.0184 | 0.123 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0042 | 0.0072 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0032 | 0.0106 | 0.0183 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0106 | 0.0183 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0022 | 0.0035 | 0.0061 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0802 | 0.5785 | 0.5785 |
Trichomonas vaginalis | esterase, putative | 0.0032 | 0.0106 | 0.0183 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0802 | 0.5785 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0497 | 0.353 | 0.6103 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0802 | 0.5785 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0106 | 0.0183 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0032 | 0.0106 | 0.0183 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0106 | 0.0183 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0106 | 0.0183 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0802 | 0.5785 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0106 | 0.0183 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0023 | 0.0042 | 0.0042 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0802 | 0.5785 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0106 | 0.0183 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0802 | 0.5785 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.0042 | 0.0072 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0802 | 0.5785 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0184 | 0.123 | 0.2126 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0023 | 0.0042 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0106 | 0.0183 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0106 | 0.0183 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0032 | 0.0106 | 0.0183 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0106 | 0.0112 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0032 | 0.0106 | 0.0183 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0032 | 0.0106 | 0.0106 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0023 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0032 | 0.0106 | 0.0183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.