Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0056 | 0.0709 | 0.2473 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0156 | 0.2651 | 0.2556 |
Brugia malayi | Carboxylesterase family protein | 0.0026 | 0.0127 | 0.004 |
Schistosoma mansoni | survival motor neuron protein | 0.0032 | 0.0242 | 0.061 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0156 | 0.2651 | 0.2776 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0041 | 0.0423 | 0.0301 |
Brugia malayi | Carboxylesterase family protein | 0.0026 | 0.0127 | 0.004 |
Loa Loa (eye worm) | carboxylesterase | 0.0153 | 0.2592 | 0.2812 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0044 | 0.0488 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.9218 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0039 | 0.0383 | 0.026 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.006 | 0.0798 | 0.0739 |
Loa Loa (eye worm) | carboxylesterase | 0.0026 | 0.0127 | 0.0137 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0026 | 0.0127 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0026 | 0.0127 | 0.0137 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0032 | 0.0242 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2592 | 0.2812 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0039 | 0.0383 | 0.1172 |
Onchocerca volvulus | 0.0032 | 0.0242 | 1 | |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0041 | 0.0423 | 0.0326 |
Brugia malayi | Carboxylesterase family protein | 0.0026 | 0.0127 | 0.004 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0039 | 0.0383 | 0.0321 |
Echinococcus multilocularis | muscleblind protein | 0.0493 | 0.9218 | 0.9208 |
Echinococcus granulosus | muscleblind protein | 0.0493 | 0.9218 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0153 | 0.2592 | 0.2498 |
Loa Loa (eye worm) | glutamate receptor | 0.0049 | 0.0578 | 0.0627 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0039 | 0.0383 | 0.026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0039 | 0.0383 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0026 | 0.0127 | 0.0148 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0039 | 0.0383 | 0.0282 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0026 | 0.0127 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0153 | 0.2592 | 0.2742 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0049 | 0.0578 | 0.0535 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0026 | 0.0127 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Echinococcus granulosus | acetylcholinesterase | 0.0153 | 0.2592 | 0.2712 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0026 | 0.0127 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Brugia malayi | Carboxylesterase family protein | 0.0153 | 0.2592 | 0.2742 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0039 | 0.0383 | 0.0415 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0026 | 0.0127 | 0.0148 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0493 | 0.9218 | 0.9208 |
Schistosoma mansoni | gliotactin | 0.0026 | 0.0127 | 0.0148 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0026 | 0.0127 | 0.0148 |
Brugia malayi | Muscleblind-like protein | 0.0493 | 0.9218 | 1 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0127 | 0.004 |
Echinococcus granulosus | carboxylesterase 5A | 0.0153 | 0.2592 | 0.2712 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0039 | 0.0383 | 0.1172 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0026 | 0.0127 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.2651 | 0.2875 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0041 | 0.0423 | 0.1333 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0153 | 0.2592 | 0.2498 |
Echinococcus multilocularis | acetylcholinesterase | 0.0153 | 0.2592 | 0.2498 |
Brugia malayi | Carboxylesterase family protein | 0.0026 | 0.0127 | 0.004 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.006 | 0.0798 | 0.068 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0026 | 0.0127 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0242 | 0.061 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0039 | 0.0383 | 0.1172 |
Brugia malayi | hypothetical protein | 0.0156 | 0.2651 | 0.2806 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0026 | 0.0127 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0153 | 0.2592 | 0.2712 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0137 |
Schistosoma mansoni | acetylcholinesterase | 0.0026 | 0.0127 | 0.0148 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0026 | 0.0127 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0153 | 0.2592 | 0.2812 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2592 | 0.2812 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0798 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.9218 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0153 | 0.2592 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.