Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0081 | 0 | 0.5 |
Onchocerca volvulus | 0.0081 | 0 | 0.5 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0118 | 0.0809 | 0.0809 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0081 | 0 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0082 | 0.0038 | 0.0038 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0 | 0.5 |
Echinococcus multilocularis | choline O acetyltransferase | 0.054 | 1 | 1 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0081 | 0 | 0.5 |
Onchocerca volvulus | 0.0081 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.054 | 1 | 1 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0081 | 0 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0081 | 0 | 0.5 |
Echinococcus granulosus | choline O acetyltransferase | 0.054 | 1 | 1 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Schistosoma mansoni | choline o-acyltransferase | 0.054 | 1 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0118 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.054 | 1 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.054 | 1 | 1 |
Onchocerca volvulus | 0.0081 | 0 | 0.5 | |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0081 | 0 | 0.5 |
Onchocerca volvulus | 0.0081 | 0 | 0.5 | |
Schistosoma mansoni | lipoxygenase | 0.0118 | 0.0809 | 0.0809 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0081 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.