Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.5946 | 0.5946 |
Loa Loa (eye worm) | fibroinase | 0.0235 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0121 | 0.4054 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0235 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1791 | 0.1791 |
Onchocerca volvulus | Cathepsin L homolog | 0.0235 | 1 | 1 |
Echinococcus granulosus | cysteine protease | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | cysteine protease | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cysteine protease | 0.0043 | 0 | 0.5 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0043 | 0 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0121 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.5946 | 0.5946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0043 | 0 | 0.5 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0235 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0043 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0235 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0157 | 0.5946 | 0.5946 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0121 | 0.4054 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0235 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0235 | 1 | 1 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Onchocerca volvulus | 0.0157 | 0.5946 | 0.5946 | |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.015 | 0.558 | 0.558 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1791 | 0.1791 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1791 | 0.1791 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.1791 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.5946 | 0.5946 |
Toxoplasma gondii | cathepsin CPL | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0235 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0078 | 0.1791 | 0.1791 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0235 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0043 | 0 | 0.5 |
Giardia lamblia | Cathepsin L-like protease | 0.0043 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.0043 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0157 | 0.5946 | 0.5946 |
Brugia malayi | Cathepsin L-like precursor | 0.0235 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0235 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0078 | 0.1791 | 0.1791 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0157 | 0.5946 | 0.5946 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0121 | 0.4054 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0078 | 0.1791 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0157 | 0.5946 | 0.5946 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Giardia lamblia | Cysteine protease | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0043 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma cruzi | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | ctsf protein | 0.0235 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0235 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0157 | 0.5946 | 0.5946 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.5946 | 0.5946 |
Onchocerca volvulus | Cathepsin F homolog | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0235 | 1 | 1 |
Schistosoma mansoni | cathepsin s | 0.0078 | 0.1791 | 0.1791 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0121 | 0.4054 | 0.4054 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Plasmodium vivax | unspecified product | 0.0078 | 0.1791 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0235 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0121 | 0.4054 | 0.4054 |
Leishmania major | cysteine peptidase A (CPA) | 0.0235 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0121 | 0.4054 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.5946 | 0.5946 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0235 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0121 | 0.4054 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0157 | 0.5946 | 0.5946 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0235 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.4054 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0235 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.5946 | 0.5946 |
Giardia lamblia | Hypothetical protein | 0.0043 | 0 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Giardia lamblia | Cysteine protease | 0.0043 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0235 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0121 | 0.4054 | 0.4054 |
Plasmodium vivax | vivapain-1 | 0.0121 | 0.4054 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0235 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0235 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0235 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0043 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0235 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0235 | 1 | 1 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0235 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Onchocerca volvulus | 0.0235 | 1 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.0132 | 0.4628 | 0.4628 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.5946 | 0.5946 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.1791 | 0.1791 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0132 | 0.4628 | 0.4628 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.4054 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.4054 | 0.4054 |
Giardia lamblia | Cathepsin L precursor | 0.0043 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1791 | 0.1791 |
Giardia lamblia | Cathepsin L-like protease | 0.0043 | 0 | 0.5 |
Onchocerca volvulus | 0.015 | 0.558 | 0.558 | |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.4054 | 0.4054 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.