Detailed information for compound 871095

Basic information

Technical information
  • TDR Targets ID: 871095
  • Name: methyl 3-[(4-methylphenyl)methyl]-4-oxo-2-sul fanylidene-1H-quinazoline-7-carboxylate
  • MW: 340.396 | Formula: C18H16N2O3S
  • H donors: 1 H acceptors: 2 LogP: 2.94 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc2c(c1)[nH]c(=S)n(c2=O)Cc1ccc(cc1)C
  • InChi: 1S/C18H16N2O3S/c1-11-3-5-12(6-4-11)10-20-16(21)14-8-7-13(17(22)23-2)9-15(14)19-18(20)24/h3-9H,10H2,1-2H3,(H,19,24)
  • InChiKey: NHHDCBKWXKVPOS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • methyl 3-[(4-methylphenyl)methyl]-4-oxo-2-thioxo-1H-quinazoline-7-carboxylate
  • 3-[(4-methylphenyl)methyl]-4-oxo-2-thioxo-1H-quinazoline-7-carboxylic acid methyl ester
  • 4-keto-3-(4-methylbenzyl)-2-thioxo-1H-quinazoline-7-carboxylic acid methyl ester
  • Oprea1_230946

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni sugar transporter 0.0029 0.0141 0.0638
Trypanosoma cruzi hexose transporter 0.0064 0.0548 0.8107
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0187 0.0284
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0339 0.1538
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0081
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0187 0.092
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0187 0.0722
Schistosoma mansoni sugar transporter 0.0029 0.0141 0.0638
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0438 0.1187
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Toxoplasma gondii facilitative glucose transporter GT1 0.0208 0.2205 0.3346
Trichomonas vaginalis glucose transporter, putative 0.0064 0.0548 0.1973
Schistosoma mansoni sugar transporter 0.0029 0.0141 0.0638
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0539 0.1458
Echinococcus multilocularis solute carrier family 22 0.0029 0.0141 0.0381
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.003 0.0081
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.0081
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0141 0.2954
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0339 0.395
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0071 0.0188
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0339 1
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0135
Loa Loa (eye worm) hypothetical protein 0.0046 0.0339 0.1422
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0643 1
Echinococcus granulosus solute carrier family 22 0.0029 0.0141 0.0381
Schistosoma mansoni polycystin 1-related 0.002 0.003 0.0135
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0141 0.0509
Onchocerca volvulus 0.0029 0.0141 0.3237
Onchocerca volvulus 0.0029 0.0141 0.3237
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0339 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0539 0.0539
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0141 0.0141
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0548 0.8107
Schistosoma mansoni protein kinase 0.0064 0.0539 0.2442
Onchocerca volvulus 0.0049 0.0372 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0187 0.092
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0187 0.3931
Echinococcus granulosus solute carrier family 22 0.0029 0.0141 0.0381
Onchocerca volvulus 0.0029 0.0141 0.3237
Loa Loa (eye worm) hypothetical protein 0.0062 0.0524 0.227
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0548 0.8107
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0548 0.1973
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0187 0.4596
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0548 0.1973
Giardia lamblia Pyruvate kinase 0.0033 0.0187 0.357
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0057 0.5
Echinococcus multilocularis pyruvate kinase 0.0033 0.0187 0.0506
Schistosoma mansoni protein kinase 0.0064 0.0539 0.2442
Schistosoma mansoni lipoxygenase 0.002 0.003 0.0135
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.003 0.003
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.0524 1
Onchocerca volvulus 0.0029 0.0141 0.3237
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0339 0.0515
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0339 0.1422
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0141 0.0381
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.0524 1
Echinococcus multilocularis pyruvate kinase 0.0026 0.0106 0.0287
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0339 0.1538
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0493 0.1335
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0258 0.212
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0524 0.227
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0141 0.2954
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0539 0.7919
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0141 0.0509
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0539 0.0539
Onchocerca volvulus 0.0029 0.0141 0.3237
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0339 0.395
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0258 1
Plasmodium vivax hexose transporter 0.0208 0.2205 0.2205
Echinococcus multilocularis pyruvate kinase 0.0033 0.0187 0.0506
Loa Loa (eye worm) hypothetical protein 0.0023 0.0071 0.0188
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0524 0.2374
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Leishmania major protein kinase, putative 0.0064 0.0539 0.7919
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Loa Loa (eye worm) hypothetical protein 0.0049 0.0372 0.1574
Brugia malayi Sugar transporter family protein 0.0029 0.0141 0.0509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0187 0.4587
Toxoplasma gondii sugar transporter ST3 0.0029 0.0141 0.0213
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0187 0.0187
Leishmania major glucose transporter/membrane transporter D2, putative 0.0064 0.0548 0.8107
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0081
Trichomonas vaginalis glucose transporter, putative 0.0064 0.0548 0.1973
Onchocerca volvulus 0.0029 0.0141 0.3237
Brugia malayi Sugar transporter family protein 0.0208 0.2205 1
Plasmodium falciparum hexose transporter 0.0208 0.2205 0.2205
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0548 0.1973
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.003 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0539 0.1927
Trypanosoma brucei glucose transporter 2A 0.0064 0.0548 0.8107
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0548 0.1973
Plasmodium falciparum mitogen-activated protein kinase 2 0.0335 0.3685 0.3685
Toxoplasma gondii protein kinase, putative 0.0586 0.6591 1
Onchocerca volvulus 0.0029 0.0141 0.3237
Echinococcus multilocularis solute carrier family 22 0.0029 0.0141 0.0381
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.0524 0.1418
Loa Loa (eye worm) sugar transporter 0.0208 0.2205 1
Entamoeba histolytica protein kinase, putative 0.0064 0.0539 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0099 0.0317
Plasmodium vivax sugar transporter, putative 0.0029 0.0141 0.0141
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0643 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0273 0.0641
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0141 0.0381
Plasmodium falciparum LCCL domain-containing protein 0.002 0.003 0.003
Brugia malayi hypothetical protein 0.0029 0.0141 0.0509
Brugia malayi hypothetical protein 0.0029 0.0141 0.0509
Trypanosoma cruzi hexose transporter, putative 0.0035 0.021 0.1383
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0141 0.0213
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0643 0.0643
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0548 0.8107
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0539 0.0539
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0524 0.2374
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0548 0.8107
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.0524 0.1855
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0643 1
Entamoeba histolytica protein kinase, putative 0.0064 0.0539 1
Leishmania major glucose transporter, lmgt3 0.0064 0.0548 0.8107
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.0524 0.227
Loa Loa (eye worm) hypothetical protein 0.0051 0.0389 0.1648
Echinococcus multilocularis solute carrier family 22 0.0029 0.0141 0.0381
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0135
Loa Loa (eye worm) hypothetical protein 0.0062 0.0524 0.227
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0539 0.0818
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0335 0.3685 0.3685
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0372 0.1688
Trypanosoma brucei glucose transporter 1E 0.0064 0.0548 0.8107
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0187 0.092
Schistosoma mansoni glucose transport protein 0.0208 0.2205 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Brugia malayi Sugar transporter family protein 0.0029 0.0141 0.0509
Mycobacterium ulcerans sugar transporter 0.0029 0.0141 0.2954
Schistosoma mansoni loxhd1 0.002 0.003 0.0135
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0339 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.0524 0.9682
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0208 0.2205 0.5972
Brugia malayi major facilitator superfamily protein 0.0029 0.0141 0.0509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0187 0.0722
Schistosoma mansoni protein kinase 0.0064 0.0539 0.2442
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0548 0.8107
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Schistosoma mansoni sugar transporter 0.0029 0.0141 0.0638
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0335 0.3685 0.5591
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0187 0.0224
Giardia lamblia Sugar-proton symporter 0.0029 0.0141 0.2687
Schistosoma mansoni glucose transporter 0.0029 0.0141 0.0638
Echinococcus multilocularis solute carrier family 22 0.0029 0.0141 0.0381
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0187 0.0722
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0187 0.4587
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.0524 0.1418
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0339 0.0961
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Echinococcus granulosus RUN 0.002 0.003 0.0081
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0141 0.0509
Echinococcus granulosus solute carrier family 22 0.0029 0.0141 0.0381
Echinococcus multilocularis RUN 0.002 0.003 0.0081
Loa Loa (eye worm) sugar transporter 0.0029 0.0141 0.0509
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Onchocerca volvulus 0.0029 0.0141 0.3237
Schistosoma mansoni hypothetical protein 0.0208 0.2205 1
Brugia malayi hypothetical protein 0.0029 0.0141 0.0509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Plasmodium vivax CDK-related protein kinase 6, putative 0.0881 1 1
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0141 0.2954
Giardia lamblia Hexose transporter 0.0029 0.0141 0.2687
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0643 1
Onchocerca volvulus 0.0029 0.0141 0.3237
Brugia malayi Cam kinase protein 1 0.0064 0.0539 0.2338
Entamoeba histolytica hypothetical protein 0.0046 0.0339 0.5737
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0187 0.0722
Onchocerca volvulus 0.0029 0.0141 0.3237
Echinococcus granulosus solute carrier family 22 0.0029 0.0141 0.0381
Schistosoma mansoni lipoxygenase 0.0055 0.0438 0.1988
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0141 0.0509
Onchocerca volvulus 0.0029 0.0141 0.3237
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0438 0.1187
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0258 1
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0548 0.8107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0187 0.0722
Onchocerca volvulus 0.0029 0.0141 0.3237
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0539 0.0539
Onchocerca volvulus 0.0029 0.0141 0.3237
Schistosoma mansoni pyruvate kinase 0.0033 0.0187 0.0848
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0339 0.0918
Echinococcus granulosus General substrate transporter 0.0178 0.1868 0.5057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Echinococcus granulosus pyruvate kinase 0.0033 0.0187 0.0506
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0141 0.5
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0539 0.0539
Onchocerca volvulus 0.0029 0.0141 0.3237
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Echinococcus multilocularis General substrate transporter 0.0178 0.1868 0.5057
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0539 0.0818
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0539 0.0539
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0493 0.1335
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0141 0.0509
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0539 0.2338
Leishmania major glucose transporter, lmgt1 0.0064 0.0548 0.8107
Leishmania major pyruvate kinase 0.0033 0.0187 0.092
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0539 0.2338
Plasmodium falciparum protein kinase 7 0.0586 0.6591 0.6591
Onchocerca volvulus 0.0029 0.0141 0.3237
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0187 0.092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0509
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0548 0.1973
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2205 0.5972
Brugia malayi major facilitator superfamily protein 0.0029 0.0141 0.0509
Schistosoma mansoni glucose transport protein 0.0208 0.2205 1
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0187 0.0722
Echinococcus granulosus pyruvate kinase 0.0033 0.0187 0.0506
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0141 0.0381
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0539 0.2338
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0643 0.0976
Echinococcus multilocularis tumor protein p63 0.0336 0.3693 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0539 0.0539
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0141 0.0638
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.2205 1
Onchocerca volvulus 0.0029 0.0141 0.3237
Chlamydia trachomatis pyruvate kinase 0.0033 0.0187 0.4596
Onchocerca volvulus Putative transporter 0.0029 0.0141 0.3237
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0339 0.0918
Schistosoma mansoni pyruvate kinase 0.0033 0.0187 0.0848
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0339 0.0339
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0643 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0064 0.0539 0.2338
Plasmodium falciparum pyruvate kinase 0.0033 0.0187 0.0187
Toxoplasma gondii sugar transporter ST2 0.0029 0.0141 0.0213
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0187 0.4587
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0539 0.0539
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0339 0.452
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0539 0.2442
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0643 0.0643
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0339 0.6476
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0339 0.0339
Leishmania major glucose transporter, lmgt2 0.0064 0.0548 0.8107
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0141 0.0381
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0187 0.0224
Schistosoma mansoni glucose transport protein 0.0208 0.2205 1
Toxoplasma gondii sugar transporter ST1 0.0029 0.0141 0.0213
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0539 0.0539
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0539 0.0818
Trypanosoma brucei glucose transporter, putative 0.0064 0.0548 0.8107
Echinococcus granulosus tumor protein p63 0.0336 0.3693 1
Leishmania major pyruvate kinase 0.0033 0.0187 0.092
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0539 0.1458
Schistosoma mansoni hypothetical protein 0.002 0.003 0.0135
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0339 0.395

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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