Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0058 | 0.0036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.1713 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0077 | 0.075 | 0.4177 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.1713 | 1 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0704 | 0.9858 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0097 | 0.104 | 0.5947 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0058 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0144 | 0.1713 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.2201 | 0.5469 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0704 | 0.9858 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0058 | 0.0174 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0149 | 0.0549 |
Onchocerca volvulus | 0.003 | 0.0069 | 0.0034 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0118 | 0.0353 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0704 | 0.9858 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0714 | 1 | 1 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0477 | 0.6556 | 0.6348 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0149 | 0.0549 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.0319 | 0.4259 | 0.3809 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0346 | 0.1032 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0227 | 0.1021 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0477 | 0.6556 | 0.6348 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0346 | 0.1032 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0256 | 0.335 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0346 | 0.1032 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0069 | 0.0062 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0149 | 0.0445 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0062 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0144 | 0.1713 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0346 | 0.1032 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0062 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0144 | 0.1713 | 1 |
Onchocerca volvulus | 0.0241 | 0.3133 | 1 | |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0058 | 0.8498 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0069 | 0.0062 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0256 | 0.335 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.0319 | 0.4259 | 0.375 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Trichomonas vaginalis | set domain proteins, putative | 0.0241 | 0.3133 | 0.9144 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0518 | 0.1546 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.2201 | 0.5469 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0367 | 0.1095 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0069 | 0.0062 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0069 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0097 | 0.104 | 0.3105 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0069 | 0.0098 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.2707 | 0.8082 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.2707 | 0.8082 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0058 | 0.0174 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0227 | 0.1053 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0058 | 0.8498 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0144 | 0.1713 | 0.5115 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0714 | 1 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0144 | 0.1713 | 0.5115 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0149 | 0.0582 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0477 | 0.6556 | 0.6348 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0069 | 0.0062 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0144 | 0.1713 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0149 | 0.0445 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0058 | 0.8498 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0118 | 0.0361 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0058 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0069 | 0.0205 |
Echinococcus granulosus | peregrin | 0.003 | 0.0058 | 0.0036 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0168 | 0.207 | 0.6542 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0144 | 0.1713 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0118 | 0.0353 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.335 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0058 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0058 | 0.0174 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0168 | 0.207 | 0.495 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0069 | 0.0205 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0149 | 0.0549 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0097 | 0.104 | 0.5932 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0069 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.