Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0032 | 0.0338 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Brugia malayi | Protein kinase domain containing protein | 0.035 | 0.928 | 0.928 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | hemicentin 1 | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Schistosoma mansoni | serine/threonine protein kinase | 0.035 | 0.928 | 1 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0032 | 0.0338 | 0.0279 |
Echinococcus multilocularis | Immunoglobulin | 0.0032 | 0.0338 | 0.0364 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0032 | 0.0338 | 0.0279 |
Brugia malayi | phosphoinositide-dependent protein kinase I | 0.035 | 0.928 | 0.928 |
Trichomonas vaginalis | AGC family protein kinase | 0.035 | 0.928 | 0.5 |
Schistosoma mansoni | nephrin | 0.0044 | 0.0683 | 0.0654 |
Echinococcus multilocularis | roundabout 2 | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Echinococcus multilocularis | neuroglian | 0.0023 | 0.0081 | 0.0088 |
Echinococcus multilocularis | peroxidasin | 0.0023 | 0.0081 | 0.0088 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0042 | 0.0629 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0973 | 0.0973 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0023 | 0.0081 | 0.0081 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | lachesin | 0.0023 | 0.0081 | 0.0088 |
Echinococcus granulosus | hemicentin 1 | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0973 | 0.0973 |
Echinococcus granulosus | neuroglian | 0.0044 | 0.0683 | 0.0736 |
Echinococcus granulosus | defective proboscis extension response | 0.0032 | 0.0338 | 0.0364 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0023 | 0.0081 | 0.0088 |
Echinococcus multilocularis | roundabout 2 | 0.0054 | 0.0973 | 0.1049 |
Entamoeba histolytica | protein kinase, putative | 0.035 | 0.928 | 0.5 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.035 | 0.928 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.035 | 0.928 | 0.928 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0023 | 0.0081 | 0.0081 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.035 | 0.928 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Trichomonas vaginalis | AGC family protein kinase | 0.035 | 0.928 | 0.5 |
Echinococcus multilocularis | roundabout 2 | 0.0023 | 0.0081 | 0.0088 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Echinococcus granulosus | roundabout 2 | 0.0054 | 0.0973 | 0.1049 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus granulosus | roundabout 2 | 0.0023 | 0.0081 | 0.0088 |
Echinococcus multilocularis | neuroglian | 0.0044 | 0.0683 | 0.0736 |
Brugia malayi | Peroxidasin | 0.0023 | 0.0081 | 0.0081 |
Trichomonas vaginalis | AGC family protein kinase | 0.035 | 0.928 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Echinococcus multilocularis | hemicentin 1 | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0375 | 1 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0081 | 0.0088 |
Onchocerca volvulus | 0.0326 | 0.8607 | 0.939 | |
Brugia malayi | Fibronectin type III domain containing protein | 0.0032 | 0.0338 | 0.0338 |
Brugia malayi | Prion-like- | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0081 | 0.0088 |
Echinococcus granulosus | roundabout 2 | 0.0023 | 0.0081 | 0.0088 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0081 | 0.0088 |
Echinococcus granulosus | contactin | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0032 | 0.0338 | 0.0364 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0338 | 0.0338 |
Echinococcus multilocularis | Immunoglobulin | 0.0032 | 0.0338 | 0.0364 |
Echinococcus granulosus | peroxidasin | 0.0023 | 0.0081 | 0.0088 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0023 | 0.0081 | 0.0088 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0023 | 0.0081 | 0.0088 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0239 | 0.6178 | 0.6178 |
Echinococcus granulosus | lachesin | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0239 | 0.6178 | 0.6178 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.035 | 0.928 | 0.928 |
Echinococcus granulosus | neuroglian | 0.0023 | 0.0081 | 0.0088 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0026 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0081 | 0.0081 |
Echinococcus granulosus | Immunoglobulin | 0.0032 | 0.0338 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0629 | 0.0629 |
Schistosoma mansoni | cell adhesion molecule | 0.0042 | 0.0629 | 0.0595 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0023 | 0.0081 | 0.0088 |
Schistosoma mansoni | tyrosine kinase | 0.003 | 0.0291 | 0.0228 |
Schistosoma mansoni | vesicular amine transporter | 0.0032 | 0.0338 | 0.0279 |
Echinococcus granulosus | twitchin | 0.0047 | 0.0776 | 0.0836 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0345 | 0.9162 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 0.0081 | 0.0081 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.