Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0429 | 0.0429 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.9512 | 0.9512 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0042 | 0.2155 | 1 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0429 | 0.0442 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.1036 | 0.2024 |
Plasmodium vivax | endoplasmin, putative | 0.0032 | 0.149 | 0.2911 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0017 | 0.0422 | 0.0435 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0063 | 0.3618 | 0.3618 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Giardia lamblia | Grp94/Hsp90 | 0.0026 | 0.1036 | 0.4808 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.1036 | 0.1036 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | Hsp90 protein | 0.0013 | 0.0174 | 0.0174 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.149 | 0.6163 |
Brugia malayi | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0013 | 0.0174 | 0.0174 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0063 | 0.3618 | 0.373 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0032 | 0.149 | 0.2911 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.149 | 0.149 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1785 | 0.1785 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0013 | 0.0174 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0017 | 0.0422 | 0.0435 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.2418 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1785 | 0.1785 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0084 | 0.512 | 1 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.2418 | 0.4723 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0013 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3722 | 0.3837 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0032 | 0.149 | 0.2911 |
Trichomonas vaginalis | endoplasmin, putative | 0.002 | 0.0628 | 0.2597 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus granulosus | phd:f box containing protein | 0.0017 | 0.0422 | 0.0435 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0042 | 0.2155 | 1 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0154 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0084 | 0.512 | 1 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0013 | 0.0174 | 0.0339 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0084 | 0.512 | 0.512 |
Loa Loa (eye worm) | endoplasmin | 0.0032 | 0.149 | 0.149 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trichomonas vaginalis | heat shock protein, putative | 0.002 | 0.0628 | 0.2597 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0032 | 0.149 | 0.6916 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0084 | 0.512 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0017 | 0.0422 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0017 | 0.0422 | 0.0422 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Schistosoma mansoni | jumonji domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0429 | 0.0429 |
Plasmodium falciparum | endoplasmin, putative | 0.002 | 0.0628 | 0.1227 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0017 | 0.0422 | 0.0422 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.149 | 0.149 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.149 | 0.149 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1785 | 0.1785 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0429 | 0.0442 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.9512 | 0.9512 |
Leishmania major | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0154 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0422 | 0.0824 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | phd:f box containing protein | 0.0017 | 0.0422 | 0.0422 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0084 | 0.512 | 1 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0084 | 0.512 | 0.512 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3722 | 0.3722 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.2954 | 0.2954 |
Plasmodium vivax | heat shock protein 86, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.149 | 0.6916 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3722 | 0.3722 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | Endoplasmin precursor | 0.0032 | 0.149 | 0.149 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0429 | 0.0429 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0084 | 0.512 | 0.5279 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.149 | 0.6916 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0026 | 0.1036 | 0.2024 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0026 | 0.1036 | 0.2024 |
Echinococcus multilocularis | heat shock protein | 0.0032 | 0.149 | 0.149 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0429 | 0.0442 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0042 | 0.2155 | 0.4209 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0019 | 0.0576 | 0.1126 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.9512 | 0.9512 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.2418 | 0.2493 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.2418 | 1 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0013 | 0.0174 | 0.0806 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0422 | 0.0422 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Trypanosoma cruzi | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.1036 | 0.1068 |
Schistosoma mansoni | protein phosphatase 2C | 0.0017 | 0.0422 | 0.0422 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0013 | 0.0174 | 0.0339 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0154 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.9512 | 0.9512 |
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0429 | 0.0429 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0026 | 0.1036 | 0.4808 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.1036 | 0.1068 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0026 | 0.1036 | 0.2024 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.2954 | 0.2954 |
Echinococcus granulosus | heat shock protein 90 | 0.0032 | 0.149 | 0.1537 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0017 | 0.0422 | 0.0422 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0422 | 0.0435 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0429 | 0.0429 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0017 | 0.0422 | 0.0824 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0026 | 0.1036 | 0.2024 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.2954 | 0.2954 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0013 | 0.0174 | 0.0339 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0429 | 0.0429 |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.1036 | 0.1068 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.1036 | 0.1036 |
Plasmodium vivax | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.9512 | 0.9807 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0017 | 0.0422 | 0.0435 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3722 | 0.3722 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Plasmodium vivax | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3722 | 0.3722 |
Schistosoma mansoni | jumonji domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Schistosoma mansoni | phd/f-box containing protein | 0.0017 | 0.0422 | 0.0422 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.149 | 0.149 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.2418 | 0.4723 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0084 | 0.512 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0017 | 0.0422 | 0.0824 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.015 | 0.9699 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0084 | 0.512 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0013 | 0.0174 | 0.0179 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0017 | 0.0422 | 0.0422 |
Plasmodium falciparum | heat shock protein 90 | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0017 | 0.0422 | 0.0422 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0084 | 0.512 | 1 |
Plasmodium vivax | JmjC domain containing protein | 0.0017 | 0.0422 | 0.0824 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.9512 | 0.9512 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0063 | 0.3618 | 0.373 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Trichomonas vaginalis | heat shock protein, putative | 0.0013 | 0.0174 | 0.0719 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.2418 | 0.4723 |
Echinococcus granulosus | heat shock protein | 0.0032 | 0.149 | 0.1537 |
Schistosoma mansoni | heat shock protein | 0.0013 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2954 | 0.2954 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.