TDR Targets

Basic information

Technical information

TDR Targets ID: 907020
Name: 1,3,5-trimethyl-9-(2-methylpropyl)-8,10-dioxa spiro[5.5]undec-3-ene
MW: 252.392 | Formula: C16H28O2
H donors: 0 H acceptors: 0 LogP: 3.86 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: CC(CC1OCC2(CO1)C(C)CC(=CC2C)C)C
InChi: 1S/C16H28O2/c1-11(2)6-15-17-9-16(10-18-15)13(4)7-12(3)8-14(16)5/h7,11,13-15H,6,8-10H2,1-5H3
InChiKey: HDDBOZWAVDQKHR-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

9-isobutyl-1,3,5-trimethyl-8,10-dioxaspiro[5.5]undec-3-ene
STOCK2S-15332

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0067	0.0353	0.0269
Brugia malayi	cathepsin L-like precursor	0.0155	0.1137	0.1137
Loa Loa (eye worm)	fibroinase	0.0215	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0238	0.0238
Trypanosoma cruzi	cysteine proteinase, putative	0.0127	0.0887	0.0887
Brugia malayi	hypothetical protein	0.0328	0.2679	0.2679
Entamoeba histolytica	cysteine protease, putative	0.0215	0.1671	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0127	0.0887	0.0887
Onchocerca volvulus		0.0215	0.1671	0.5667
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0127	0.0887	0.266
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0067	0.0353	0.0353
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1151	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0067	0.0353	0.0269
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.1151	1	1
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0127	0.0887	0.531
Loa Loa (eye worm)	hypothetical protein	0.1151	1	1
Plasmodium vivax	vivapain-1	0.0127	0.0887	0.531
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0127	0.0887	0.0809
Brugia malayi	Cathepsin L-like precursor	0.006	0.0291	0.0291
Onchocerca volvulus	Cathepsin L homolog	0.0215	0.1671	0.5667
Schistosoma mansoni	cathepsin C	0.0067	0.0353	0.0269
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1151	1	1
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0067	0.0353	0.2112
Schistosoma mansoni	cathepsin s	0.006	0.0291	0.0207
Plasmodium vivax	vivapain-3	0.0127	0.0887	0.531
Plasmodium falciparum	serine repeat antigen 4	0.0067	0.0353	0.2112
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0067	0.0353	0.2112
Trypanosoma cruzi	cysteine peptidase, putative	0.006	0.0291	0.0291
Entamoeba histolytica	cysteine proteinase, putative	0.0127	0.0887	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0215	0.1671	0.4419
Brugia malayi	Papain family cysteine protease containing protein	0.0215	0.1671	0.1671
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0215	0.1671	0.4419
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0067	0.0353	0.2112
Loa Loa (eye worm)	cathepsin B	0.0402	0.3337	0.3337
Entamoeba histolytica	cysteine proteinase, putative	0.0215	0.1671	1
Plasmodium vivax	serine-repeat antigen (SERA)	0.0067	0.0353	0.2112
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0067	0.0353	0.0353
Loa Loa (eye worm)	cysteine protease	0.0215	0.1671	0.1671
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Brugia malayi	cathepsin F-like cysteine proteinase	0.006	0.0291	0.0291
Loa Loa (eye worm)	ctsf protein	0.0215	0.1671	0.1671
Echinococcus multilocularis	cysteine protease	0.0215	0.1671	0.1367
Plasmodium falciparum	serine repeat antigen 2	0.0067	0.0353	0.2112
Entamoeba histolytica	cysteine proteinase 2	0.0127	0.0887	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0127	0.0887	0.266
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0067	0.0353	0.0353
Plasmodium vivax	unspecified product	0.0067	0.0353	0.2112
Trypanosoma cruzi	cysteine peptidase, putative	0.0215	0.1671	0.1671
Onchocerca volvulus		0.0215	0.1671	0.5667
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0067	0.0353	0.2112
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1151	1	1
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0086	0.0086
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0215	0.1671	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0215	0.1671	0.1367
Brugia malayi	Cathepsin L-like precursor	0.0155	0.1137	0.1137
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0127	0.0887	0.0809
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Schistosoma mansoni	cathepsin B (C01 family)	0.0067	0.0353	0.0269
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Giardia lamblia	Cathepsin B precursor	0.0402	0.3337	1
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0067	0.0353	0.0269
Loa Loa (eye worm)	hypothetical protein	0.0328	0.2679	0.2679
Plasmodium falciparum	serine repeat antigen 3	0.0067	0.0353	0.2112
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0067	0.0353	0.2112
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0067	0.0353	0.2112
Loa Loa (eye worm)	hypothetical protein	0.006	0.0291	0.0291
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0067	0.0353	0.2112
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Loa Loa (eye worm)	hypothetical protein	0.006	0.0291	0.0291
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Giardia lamblia	Cathepsin B precursor	0.0402	0.3337	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0215	0.1671	0.1671
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Brugia malayi	cathepsin L-like cysteine proteinase	0.0067	0.0353	0.0353
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Trypanosoma cruzi	cysteine peptidase, putative	0.0215	0.1671	0.1671
Giardia lamblia	Cathepsin B precursor	0.0402	0.3337	1
Onchocerca volvulus		0.0155	0.1137	0.337
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0054	0.0238	0.0238
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0215	0.1671	0.1367
Brugia malayi	Papain family cysteine protease containing protein	0.0127	0.0887	0.0887
Echinococcus multilocularis	cysteine protease	0.0215	0.1671	0.1367
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Onchocerca volvulus		0.0328	0.2679	1
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Toxoplasma gondii	cathepsin B	0.0402	0.3337	1
Onchocerca volvulus	Cathepsin F homolog	0.0215	0.1671	0.5667
Loa Loa (eye worm)	hypothetical protein	0.0155	0.1137	0.1137
Entamoeba histolytica	cysteine proteinase, putative	0.0127	0.0887	0.4054
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0067	0.0353	0.1058
Trypanosoma cruzi	major cysteine proteinase, putative	0.0067	0.0353	0.0353
Plasmodium vivax	vivapain-2	0.0215	0.1671	1
Entamoeba histolytica	cysteine proteinase, putative	0.0215	0.1671	1
Echinococcus multilocularis	cathepsin L	0.0127	0.0887	0.0554
Echinococcus granulosus	cathepsin b	0.1151	1	1
Brugia malayi	Papain family cysteine protease containing protein	0.0127	0.0887	0.0887
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Echinococcus multilocularis	cathepsin L cysteine protease	0.0215	0.1671	0.1367
Entamoeba histolytica	cysteine proteinase, putative	0.0127	0.0887	0.4054
Onchocerca volvulus	Cathepsin L homolog	0.0215	0.1671	0.5667
Leishmania major	cysteine peptidase A (CPA)	0.0215	0.1671	0.5009
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.006	0.0291	0.0291
Schistosoma mansoni	cathepsin S (C01 family)	0.0067	0.0353	0.0269
Plasmodium falciparum	serine repeat antigen 1	0.0067	0.0353	0.2112
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Plasmodium vivax	unspecified product	0.006	0.0291	0.1739
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0402	0.3337	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0155	0.1137	0.1137
Brugia malayi	Papain family cysteine protease containing protein	0.0067	0.0353	0.0353
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0067	0.0353	0.2112
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0067	0.0353	0.2112
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0067	0.0353	0.0269
Brugia malayi	fibroinase precursor	0.0067	0.0353	0.0353
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.1151	1	1
Plasmodium falciparum	serine repeat antigen 7	0.0067	0.0353	0.2112
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0127	0.0887	0.0887
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Toxoplasma gondii	cathepsin CPC1	0.0067	0.0353	0.1058
Echinococcus multilocularis	cathepsin b	0.1151	1	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0127	0.0887	0.4054
Echinococcus granulosus	cathepsin b	0.1151	1	1
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Echinococcus multilocularis	cathepsin b	0.1151	1	1
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Toxoplasma gondii	cathepsin CPL	0.0215	0.1671	0.5009
Trypanosoma cruzi	cysteine protease, putative	0.0127	0.0887	0.0887
Schistosoma mansoni	cathepsin F (C01 family)	0.0215	0.1671	0.1599
Loa Loa (eye worm)	hypothetical protein	0.0155	0.1137	0.1137
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0402	0.3337	0.3279
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0054	0.0238	0.0238
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0215	0.1671	1
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0127	0.0887	0.1791
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Onchocerca volvulus		0.0215	0.1671	0.5667
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0067	0.0353	0.0353
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0067	0.0353	0.0269
Brugia malayi	Cathepsin L-like precursor	0.0155	0.1137	0.1137
Trypanosoma cruzi	cysteine peptidase, putative	0.0127	0.0887	0.0887
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0127	0.0887	0.1791
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0067	0.0353	0.2112
Plasmodium vivax	unspecified product	0.0127	0.0887	0.531
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0155	0.1137	0.2627
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0402	0.3337	1
Onchocerca volvulus		0.0215	0.1671	0.5667
Onchocerca volvulus		0.0215	0.1671	0.5667
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0067	0.0353	0.0269
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0215	0.1671	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0127	0.0887	0.0554
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Entamoeba histolytica	cysteine proteinase, putative	0.0127	0.0887	0.4054
Schistosoma mansoni	cathepsin F (C01 family)	0.0215	0.1671	0.1599
Plasmodium falciparum	serine repeat antigen 9	0.0067	0.0353	0.2112
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0067	0.0353	0.0353
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0067	0.0353	0.2112
Plasmodium vivax	serine-repeat antigen (SERA)	0.0067	0.0353	0.2112
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0155	0.1137	0.1137
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0054	0.0238	0.0238
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.006	0.0291	0.0291
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma cruzi	cruzipain precursor, putative	0.006	0.0291	0.0291
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0067	0.0353	0.0269
Schistosoma mansoni	cathepsin F (C01 family)	0.0155	0.1137	0.106
Echinococcus granulosus	cathepsin l1	0.0155	0.1137	0.0813
Plasmodium falciparum	serine repeat antigen 8	0.0067	0.0353	0.2112
Loa Loa (eye worm)	hypothetical protein	0.006	0.0291	0.0291
Loa Loa (eye worm)	hypothetical protein	0.0215	0.1671	0.1671
Trypanosoma cruzi	major cysteine proteinase, putative	0.0067	0.0353	0.0353
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0067	0.0353	0.2112
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0155	0.1137	0.2627
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Echinococcus granulosus	cathepsin L	0.0127	0.0887	0.0554
Leishmania major	cathepsin L-like protease	0.0215	0.1671	0.5009
Plasmodium vivax	vivapain-2	0.0215	0.1671	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma cruzi	cysteine peptidase, putative	0.0215	0.1671	0.1671
Echinococcus granulosus	cathepsin l1	0.0215	0.1671	0.1367
Echinococcus multilocularis	cathepsin L cysteine protease	0.0215	0.1671	0.1367
Plasmodium falciparum	serine repeat antigen 5	0.0067	0.0353	0.2112
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0215	0.1671	0.1671
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Brugia malayi	cathepsin L precursor	0.0067	0.0353	0.0353
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0067	0.0353	0.0269
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0067	0.0353	0.0269
Entamoeba histolytica	cysteine proteinase, putative	0.0155	0.1137	0.5946
Brugia malayi	cathepsin F-like cysteine proteinase	0.0067	0.0353	0.0353
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0215	0.1671	0.1367
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0402	0.3337	1
Brugia malayi	Papain family cysteine protease containing protein	0.0067	0.0353	0.0353
Brugia malayi	latrophilin 2 splice variant baaae	0.0037	0.0086	0.0086
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0127	0.0887	0.0809
Trypanosoma cruzi	cruzipain precursor, putative	0.0215	0.1671	0.1671
Toxoplasma gondii	cathepsin CPC2	0.0067	0.0353	0.1058
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054
Echinococcus granulosus	cysteine protease	0.0127	0.0887	0.0554
Plasmodium falciparum	serine repeat antigen 6	0.0067	0.0353	0.2112
Onchocerca volvulus		0.0215	0.1671	0.5667
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0402	0.3337	0.3337
Trypanosoma cruzi	cysteine peptidase, putative	0.0215	0.1671	0.1671
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0215	0.1671	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0215	0.1671	0.5009
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0215	0.1671	0.4419
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0067	0.0353	0.0353
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0067	0.0353	0.2112
Onchocerca volvulus		0.0215	0.1671	0.5667
Brugia malayi	Cathepsin L-like precursor	0.0215	0.1671	0.1671
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0215	0.1671	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0353	0.0353
Brugia malayi	Papain family cysteine protease containing protein	0.0067	0.0353	0.0353
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0155	0.1137	0.1137
Entamoeba histolytica	cysteine protease, putative	0.0127	0.0887	0.4054

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 907020