Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Echinococcus multilocularis | ectonucleotide | 0.0477 | 0.1101 | 0.2342 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.034 | 0.0755 | 0.3414 |
Onchocerca volvulus | 0.1221 | 0.2986 | 1 | |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0477 | 0.1101 | 0.4983 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.1221 | 0.2986 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0477 | 0.1101 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.1327 | 0.4211 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0142 | 0.0254 | 0.0137 |
Trypanosoma brucei | endonuclease G, putative | 0.034 | 0.0755 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Brugia malayi | hypothetical protein | 0.0177 | 0.0341 | 0.0775 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0549 | 0.1284 | 0.581 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0341 | 0.0775 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0914 | 0.221 | 0.2116 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.1221 | 0.2986 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1221 | 0.2986 | 0.2902 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.1327 | 0.4211 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0565 | 0.1327 | 0.1222 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.034 | 0.0755 | 1 |
Toxoplasma gondii | MAPEG family protein | 0.0914 | 0.221 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.6002 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.034 | 0.0755 | 0.5 |
Onchocerca volvulus | 0.0565 | 0.1327 | 0.4211 | |
Leishmania major | endonuclease G, putative | 0.034 | 0.0755 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.1327 | 0.4211 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0914 | 0.221 | 0.4987 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0314 | 0.0691 | 1 |
Onchocerca volvulus | 0.0177 | 0.0341 | 0.0775 | |
Trypanosoma brucei | endonuclease G, putative | 0.034 | 0.0755 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0549 | 0.1284 | 0.2778 |
Plasmodium falciparum | GPI ethanolamine phosphate transferase 3, putative | 0.0089 | 0.0119 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.034 | 0.0755 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0142 | 0.0254 | 0.0322 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0154 | 0.0283 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Trypanosoma cruzi | endonuclease G, putative | 0.034 | 0.0755 | 0.5 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0138 | 0.0244 | 0.1106 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.6002 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0565 | 0.1327 | 0.1222 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Onchocerca volvulus | 0.0565 | 0.1327 | 0.4211 | |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.0356 | 0.0239 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.034 | 0.0755 | 0.5 |
Schistosoma mansoni | endonuclease related | 0.034 | 0.0755 | 0.0643 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Echinococcus granulosus | ectonucleotide | 0.0477 | 0.1101 | 0.4983 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.0356 | 0.0239 |
Echinococcus granulosus | Endonuclease G | 0.034 | 0.0755 | 0.3414 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0565 | 0.1327 | 0.4211 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Loa Loa (eye worm) | acetyltransferase | 0.0142 | 0.0254 | 0.0471 |
Echinococcus multilocularis | Endonuclease G | 0.034 | 0.0755 | 0.1515 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.2879 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 0.1101 | 0.3425 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1744 | 0.4312 | 1 |
Echinococcus granulosus | gpi ethanolamine phosphate transferase 3 | 0.0089 | 0.0119 | 0.054 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0914 | 0.221 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.034 | 0.0755 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.6002 |
Echinococcus multilocularis | geminin | 0.0182 | 0.0356 | 0.0564 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.6002 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0565 | 0.1327 | 0.1222 |
Echinococcus granulosus | neuropeptide s receptor | 0.0549 | 0.1284 | 0.581 |
Echinococcus granulosus | geminin | 0.0182 | 0.0356 | 0.1611 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0142 | 0.0254 | 0.0471 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0314 | 0.0691 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0549 | 0.1284 | 0.2778 |
Echinococcus granulosus | transferase | 0.0089 | 0.0119 | 0.054 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0565 | 0.1327 | 0.6002 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0565 | 0.1327 | 0.1222 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0089 | 0.0119 | 0.054 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0154 | 0.0283 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0314 | 0.0691 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0154 | 0.0283 | 1 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.034 | 0.0755 | 0.2216 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.