Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0073 | 0.0426 | 0.0426 |
Echinococcus granulosus | snurportin 1 | 0.033 | 0.3587 | 0.3587 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0426 | 0.0426 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0073 | 0.0426 | 0.4864 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0073 | 0.0426 | 0.0426 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.0426 | 1 |
Brugia malayi | Hhat protein | 0.0073 | 0.0426 | 0.0426 |
Treponema pallidum | alginate O-acetylation protein (algI) | 0.0073 | 0.0426 | 0.5 |
Toxoplasma gondii | melibiase subfamily protein | 0.011 | 0.0875 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0073 | 0.0424 | 0.0424 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0073 | 0.0426 | 0.0426 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0073 | 0.0426 | 0.5 |
Trypanosoma cruzi | GUP1, putative | 0.0073 | 0.0426 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0073 | 0.0426 | 0.4864 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0073 | 0.0426 | 0.0426 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Brugia malayi | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.011 | 0.0875 | 0.0875 |
Schistosoma mansoni | hypothetical protein | 0.033 | 0.3587 | 0.3587 |
Schistosoma mansoni | alpha-glucosidase | 0.0151 | 0.1374 | 0.1374 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | alpha-glucosidase | 0.0151 | 0.1374 | 0.1374 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | snurportin 1 | 0.033 | 0.3587 | 0.3587 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0175 | 0.1674 | 0.1674 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0073 | 0.0426 | 0.5 |
Brugia malayi | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | MBOAT family protein | 0.0852 | 1 | 1 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.033 | 0.3587 | 0.3587 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.0852 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.0426 | 1 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | zinc finger protein | 0.0852 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0073 | 0.0426 | 1 |
Loa Loa (eye worm) | hhat protein | 0.0073 | 0.0426 | 0.0426 |
Leishmania major | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0073 | 0.0426 | 1 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0073 | 0.0426 | 0.0426 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0426 | 0.0426 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0073 | 0.0426 | 1 |
Loa Loa (eye worm) | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Echinococcus granulosus | zinc finger protein | 0.0778 | 0.9097 | 0.9097 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | hhat protein | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0073 | 0.0426 | 0.0426 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0073 | 0.0424 | 0.9974 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0073 | 0.0424 | 0.0424 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0073 | 0.0426 | 0.0426 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0426 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0426 | 0.0426 |
Leishmania major | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0073 | 0.0426 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0175 | 0.1674 | 0.1674 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0073 | 0.0426 | 0.0426 |
Brugia malayi | Melibiase family protein | 0.0073 | 0.0424 | 0.0424 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0175 | 0.1674 | 0.1674 |
Onchocerca volvulus | 0.0101 | 0.0767 | 1 | |
Trypanosoma cruzi | GUP1, putative | 0.0073 | 0.0426 | 1 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0073 | 0.0426 | 0.0426 |
Brugia malayi | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Leishmania major | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Trichomonas vaginalis | porcupine, putative | 0.0073 | 0.0426 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Leishmania major | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.0426 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0175 | 0.1674 | 0.1674 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0426 | 1 |
Brugia malayi | MBOAT family protein | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | zinc finger protein | 0.0778 | 0.9097 | 0.9097 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0073 | 0.0426 | 0.4864 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0073 | 0.0426 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0088 | 0.0605 | 0.0605 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0073 | 0.0426 | 0.0426 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0073 | 0.0426 | 0.0426 |
Brugia malayi | diacylglycerol acyltransferase | 0.0073 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0424 | 0.0424 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.0852 | 1 | 1 |
Leishmania major | glycerol uptake protein, putative | 0.0073 | 0.0426 | 1 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0073 | 0.0426 | 0.0426 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0175 | 0.1674 | 0.1674 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.011 | 0.0875 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0426 | 0.0426 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0426 | 0.0426 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0073 | 0.0426 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.