Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.1001 | 0.091 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0383 | 0.0285 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0221 | 0.9883 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.1093 | 0.1018 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0236 | 0.0137 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0216 | 0.0491 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0383 | 0.0869 |
Echinococcus multilocularis | ras gtpase | 0.036 | 0.44 | 0.4343 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0106 | 0.12 | 0.6396 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0309 | 0.0227 |
Echinococcus multilocularis | dna polymerase eta | 0.0044 | 0.0414 | 0.0317 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0295 | 0.3579 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.1594 | 0.1509 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0383 | 0.0285 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.1074 | 0.2442 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.1074 | 0.0984 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.1038 | 0.0947 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0295 | 0.3579 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0309 | 0.0211 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.0675 | 0.1534 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0221 | 0.0123 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.0104 | 0.0236 |
Brugia malayi | Ras-related protein R-Ras2 | 0.036 | 0.44 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0364 | 0.0282 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0317 | 0.0235 |
Onchocerca volvulus | 0.0035 | 0.0309 | 0.0296 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0044 | 0.0414 | 0.109 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.1025 | 0.2659 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0385 | 0.0819 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0081 | 0.0882 | 0.0789 |
Trichomonas vaginalis | dexras1, putative | 0.036 | 0.44 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1622 | 0.4373 |
Brugia malayi | Bromodomain containing protein | 0.0028 | 0.0221 | 0.0503 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0333 | 0.0235 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0236 | 0.0137 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0221 | 0.0503 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0224 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.025 | 0.043 |
Onchocerca volvulus | 0.0058 | 0.0589 | 0.1191 | |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.1074 | 0.2266 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.025 | 0.043 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.01 | 0.0207 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0383 | 0.0869 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.1594 | 0.1509 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0221 | 0.0017 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0309 | 0.0211 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0383 | 0.0657 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0243 | 0.2928 | 0.6654 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0309 | 0.0702 |
Schistosoma mansoni | apoptosis regulator bax | 0.0081 | 0.0882 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.036 | 0.44 | 1 |
Entamoeba histolytica | ras-1, putative | 0.036 | 0.44 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1025 | 0.2659 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0385 | 0.0819 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.1025 | 0.2581 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0106 | 0.12 | 0.1111 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.0675 | 0.1337 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0414 | 0.094 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.01 | 0.0016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.12 | 0.3304 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0383 | 0.0285 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0383 | 0.0869 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0675 | 0.1652 |
Onchocerca volvulus | 0.0176 | 0.2082 | 0.5955 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0438 | 0.0786 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.3579 | 1 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0081 | 0.0882 | 0.0805 |
Schistosoma mansoni | hypothetical protein | 0.04 | 0.4896 | 0.4853 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.01 | 0.0227 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0106 | 0.12 | 0.5 |
Echinococcus granulosus | peregrin | 0.0028 | 0.0221 | 0.0123 |
Echinococcus multilocularis | dnaJ subfamily B | 0.04 | 0.4896 | 0.4845 |
Echinococcus multilocularis | peregrin | 0.0028 | 0.0221 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0364 | 0.0282 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0221 | 0.0503 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0805 | 1 | 1 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0106 | 0.12 | 0.6396 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0236 | 0.0154 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0589 | 0.051 |
Entamoeba histolytica | Ras family GTPase | 0.036 | 0.44 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0224 | 0.724 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 0.0414 | 0.0901 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0438 | 0.0786 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0456 | 0.036 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Echinococcus granulosus | dna polymerase eta | 0.0044 | 0.0414 | 0.0317 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1622 | 0.4373 |
Onchocerca volvulus | 0.0277 | 0.335 | 1 | |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0216 | 0.0491 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.1025 | 0.233 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0362 | 0.0264 |
Echinococcus multilocularis | tumor protein p63 | 0.0394 | 0.4826 | 0.4774 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0285 | 0.0187 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.0796 | 0.0718 |
Echinococcus granulosus | ras gtpase | 0.036 | 0.44 | 0.4343 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0675 | 0.0581 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0029 | 0.0224 | 0.008 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.01 | 0.0016 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1074 | 0.2442 |
Schistosoma mansoni | DNA polymerase eta | 0.0044 | 0.0414 | 0.0333 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0309 | 0.0227 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0029 | 0.0224 | 0.008 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.3579 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0882 | 0.0805 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0221 | 0.1311 |
Schistosoma mansoni | kinase | 0.0047 | 0.0453 | 0.0373 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0106 | 0.12 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0882 | 0.0805 |
Trichomonas vaginalis | GTP-binding protein rit, putative | 0.036 | 0.44 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0221 | 0.0503 |
Trichomonas vaginalis | ral, putative | 0.036 | 0.44 | 1 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0383 | 0.0301 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.2082 | 0.4733 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0792 | 0.9842 | 0.984 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0221 | 0.0123 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.01 | 0.0207 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.182 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.1025 | 0.0934 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0029 | 0.0224 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0221 | 0.0139 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0675 | 0.1534 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0309 | 1 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.1025 | 1 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0221 | 0.0139 |
Echinococcus granulosus | dnaJ subfamily B | 0.04 | 0.4896 | 0.4845 |
Brugia malayi | Pre-SET motif family protein | 0.0243 | 0.2928 | 0.6654 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0317 | 0.0721 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0317 | 0.0721 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.1001 | 0.091 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0364 | 0.0282 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0309 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0309 | 0.0702 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Trichomonas vaginalis | set domain proteins, putative | 0.0277 | 0.335 | 0.7559 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0081 | 0.0882 | 0.2004 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0224 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0882 | 0.2004 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0362 | 0.0264 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.05 | 0.1148 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0385 | 0.101 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Loa Loa (eye worm) | phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Brugia malayi | hypothetical protein | 0.0176 | 0.2082 | 0.4733 |
Loa Loa (eye worm) | Ras protein let-60 | 0.036 | 0.44 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0882 | 0.0805 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0221 | 0.7155 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.12 | 0.1126 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.05 | 0.1135 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0317 | 0.0235 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0675 | 0.1825 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.1025 | 0.0934 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0383 | 0.0285 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1025 | 0.2659 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0309 | 0.0227 |
Trichomonas vaginalis | rap1 and, putative | 0.036 | 0.44 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0309 | 0.0211 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.1025 | 0.2811 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0385 | 0.0819 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0216 | 0.0133 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0297 | 0.0199 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.12 | 0.3162 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0628 | 0.0549 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0224 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0603 | 0.1371 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.1025 | 0.233 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus granulosus | tumor protein p63 | 0.0394 | 0.4826 | 0.4774 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1025 | 0.0949 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0805 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0478 | 0.1086 |
Trichomonas vaginalis | ras-dva small GTPase, putative | 0.036 | 0.44 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0106 | 0.12 | 0.1111 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.0224 | 0.1339 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.0224 | 0.0288 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.0675 | 0.1652 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.1038 | 0.0947 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.1622 | 0.449 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0081 | 0.0882 | 0.0789 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.1038 | 0.2359 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.1074 | 0.0984 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1025 | 0.2151 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.182 | 1 |
Entamoeba histolytica | Ras family GTPase | 0.036 | 0.44 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0548 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0224 | 1 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0081 | 0.0882 | 0.2004 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0224 | 0.0288 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0333 | 0.0235 |
Brugia malayi | phosphofructokinase | 0.0106 | 0.12 | 0.2728 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0317 | 0.0219 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0309 | 0.2675 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.1025 | 0.2151 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0462 | 0.7362 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0081 | 0.0882 | 0.0789 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0675 | 0.0581 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0589 | 0.1339 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 0.0414 | 0.0901 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0081 | 0.0882 | 0.0789 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.12 | 0.1126 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.01 | 0.0227 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.01 | 0.0207 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0044 | 0.0414 | 0.094 |
Trichomonas vaginalis | rheb, putative | 0.036 | 0.44 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0224 | 0.724 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.12 | 0.2559 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0106 | 0.12 | 0.3162 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0675 | 0.0596 |
Brugia malayi | Ras protein let-60 | 0.036 | 0.44 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0031 | 0.025 | 0.0869 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0236 | 0.0154 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0364 | 0.0282 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0675 | 0.1652 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibition of DPP9 | ChEMBL. | 18556199 |
IC50 (binding) | = 228 uM | Inhibition of DPP2 | ChEMBL. | 18556199 |
IC50 (binding) | = 374 uM | Inhibition of DPP4 | ChEMBL. | 18556199 |
IC50 (binding) | = 612 uM | Inhibition of DPP8 | ChEMBL. | 18556199 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.