Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.8173 | 0.8173 |
Onchocerca volvulus | 0.0029 | 0.0626 | 0.0191 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0031 | 0.069 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0054 | 0.1627 | 0.1908 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.002 | 0.0258 | 0.021 |
Mycobacterium tuberculosis | Probable gamma-glutamyltranspeptidase precursor GgtB (gamma-glutamyltransferase) (glutamyl transpeptidase) | 0.0146 | 0.531 | 0.72 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0017 | 0.0142 | 0.0055 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0031 | 0.069 | 0.0814 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0025 | 0.0445 | 0.0424 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0054 | 0.1627 | 0.1627 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0033 | 0.0795 | 0.0776 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0018 | 0.0184 | 0.1404 |
Schistosoma mansoni | lamin | 0.0029 | 0.0626 | 0.0531 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0626 | 0.0671 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0033 | 0.0795 | 0.0701 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.069 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0626 | 0.0606 |
Trichomonas vaginalis | ran, putative | 0.0018 | 0.0184 | 0.0111 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0795 | 0.088 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0016 | 0.0101 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.069 | 0.0789 |
Mycobacterium ulcerans | bifunctional acylase, GgtA | 0.0071 | 0.232 | 1 |
Schistosoma mansoni | ran | 0.0018 | 0.0184 | 0.0084 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0025 | 0.0479 | 0.0459 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0025 | 0.0479 | 0.0382 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0025 | 0.0479 | 0.0382 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.069 | 0.0789 |
Trichomonas vaginalis | esterase, putative | 0.0031 | 0.069 | 0.0789 |
Brugia malayi | beta-lactamase | 0.0031 | 0.069 | 0.075 |
Brugia malayi | RNA, U transporter 1 | 0.007 | 0.2265 | 0.2697 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0018 | 0.0165 | 0.0144 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0033 | 0.0795 | 0.0776 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0626 | 0.0606 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0031 | 0.069 | 0.0814 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0626 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.5129 | 0.5129 |
Plasmodium vivax | importin-beta 2, putative | 0.0025 | 0.0445 | 0.5831 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0017 | 0.0142 | 0.0055 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Echinococcus granulosus | tar DNA binding protein | 0.0054 | 0.1627 | 0.1609 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0795 | 0.0701 |
Loa Loa (eye worm) | RNA binding protein | 0.0054 | 0.1627 | 0.1627 |
Onchocerca volvulus | 0.0217 | 0.8173 | 1 | |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0017 | 0.0142 | 0.0055 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.069 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0017 | 0.0142 | 0.0055 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.069 | 0.0814 |
Trichomonas vaginalis | set domain proteins, putative | 0.0202 | 0.757 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0025 | 0.0479 | 0.0459 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0018 | 0.0165 | 0.0144 |
Brugia malayi | RNA binding protein | 0.0054 | 0.1627 | 0.1908 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0018 | 0.0184 | 0.1404 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.8173 | 0.8173 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0626 | 0.0626 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0018 | 0.0184 | 1 |
Schistosoma mansoni | single-minded | 0.0066 | 0.2094 | 0.2013 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.002 | 0.0258 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.069 | 0.0814 |
Brugia malayi | Gamma-glutamyltranspeptidase family protein | 0.0071 | 0.232 | 0.2764 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0031 | 0.069 | 0.0814 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0626 | 0.0606 |
Brugia malayi | beta-lactamase family protein | 0.0031 | 0.069 | 0.075 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0025 | 0.0445 | 0.5831 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0795 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.564 | 0.564 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0479 | 0.0479 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0025 | 0.0442 | 0.0421 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0031 | 0.069 | 0.067 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0017 | 0.0142 | 0.0055 |
Schistosoma mansoni | tar DNA-binding protein | 0.0054 | 0.1627 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0018 | 0.0165 | 0.0165 |
Onchocerca volvulus | 0.0031 | 0.069 | 0.0274 | |
Brugia malayi | Pre-SET motif family protein | 0.0025 | 0.0479 | 0.049 |
Toxoplasma gondii | ABC1 family protein | 0.0031 | 0.069 | 1 |
Onchocerca volvulus | 0.0031 | 0.069 | 0.0274 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | gamma-glutamyl transpeptidase | 0.0217 | 0.8173 | 0.8173 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0795 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1441 | 0.1353 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0445 | 0.0445 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0018 | 0.0184 | 0.0163 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0018 | 0.0184 | 0.1404 |
Entamoeba histolytica | Ran family GTPase | 0.0018 | 0.0184 | 0.1191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0017 | 0.0142 | 0.0055 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0025 | 0.0479 | 0.0459 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.069 | 0.0814 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0018 | 0.0184 | 0.1404 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0031 | 0.069 | 0.2655 |
Echinococcus granulosus | gamma glutamyltransferase 1 | 0.0217 | 0.8173 | 0.8169 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Loa Loa (eye worm) | beta-lactamase | 0.0031 | 0.069 | 0.069 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0017 | 0.0142 | 0.0055 |
Leishmania major | GTP-binding protein, putative | 0.0018 | 0.0184 | 0.1404 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1441 | 0.1353 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0017 | 0.0142 | 0.0055 |
Onchocerca volvulus | 0.0141 | 0.5129 | 0.6044 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0031 | 0.069 | 0.0814 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0031 | 0.069 | 0.0814 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.069 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0154 | 0.564 | 0.6869 |
Echinococcus multilocularis | 0.0217 | 0.8173 | 0.8169 | |
Onchocerca volvulus | 0.0031 | 0.069 | 0.0274 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0031 | 0.069 | 0.0814 |
Echinococcus multilocularis | gamma glutamyltransferase 1 | 0.0217 | 0.8173 | 0.8169 |
Onchocerca volvulus | 0.0029 | 0.0626 | 0.0191 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0031 | 0.069 | 0.0595 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0016 | 0.0101 | 0.008 |
Echinococcus granulosus | importin subunit beta 1 | 0.0025 | 0.0445 | 0.0424 |
Onchocerca volvulus | 0.0202 | 0.757 | 0.9217 | |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0017 | 0.0142 | 0.0055 |
Echinococcus granulosus | single minded 2 | 0.0049 | 0.1409 | 0.139 |
Trichomonas vaginalis | importin beta-1, putative | 0.002 | 0.0258 | 0.021 |
Echinococcus granulosus | gamma glutamyltranspeptidase 1 | 0.0217 | 0.8173 | 0.8169 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0263 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.8173 | 0.8173 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0031 | 0.069 | 0.075 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0025 | 0.0479 | 0.0382 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0017 | 0.0142 | 0.0055 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0031 | 0.069 | 0.0789 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.002 | 0.0258 | 0.266 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0142 | 0.5152 | 0.5142 |
Mycobacterium ulcerans | putative regulatory protein | 0.0049 | 0.1409 | 0.5893 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0025 | 0.0445 | 0.5831 |
Schistosoma mansoni | tar DNA-binding protein | 0.0054 | 0.1627 | 0.1541 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.576 | 0.5717 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0124 | 0.4444 | 0.5391 |
Mycobacterium ulcerans | lipase LipD | 0.0031 | 0.069 | 0.2655 |
Echinococcus multilocularis | snurportin 1 | 0.0263 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.069 | 0.0789 |
Schistosoma mansoni | tar DNA-binding protein | 0.0054 | 0.1627 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.4444 | 0.4444 |
Onchocerca volvulus | 0.0217 | 0.8173 | 1 | |
Echinococcus multilocularis | transfer RNA-Lys | 0.0049 | 0.1409 | 0.139 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0031 | 0.069 | 0.0814 |
Schistosoma mansoni | ran | 0.0018 | 0.0184 | 0.0084 |
Brugia malayi | Gamma-glutamyltranspeptidase family protein | 0.0217 | 0.8173 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0154 | 0.564 | 0.6708 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0017 | 0.0142 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0626 | 0.0671 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0196 | 0.7335 | 1 |
Entamoeba histolytica | hypothetical protein | 0.002 | 0.0258 | 0.2257 |
Brugia malayi | Pre-SET motif family protein | 0.0178 | 0.6585 | 0.8037 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0031 | 0.069 | 0.0789 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0025 | 0.0479 | 0.0382 |
Schistosoma mansoni | lamin | 0.0029 | 0.0626 | 0.0531 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0031 | 0.069 | 0.2655 |
Echinococcus multilocularis | tar DNA binding protein | 0.0054 | 0.1627 | 0.1609 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0017 | 0.0142 | 0.0055 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0016 | 0.0101 | 0.008 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0018 | 0.0184 | 0.1404 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0031 | 0.069 | 0.0595 |
Mycobacterium ulcerans | hypothetical protein | 0.0031 | 0.069 | 0.2655 |
Leishmania major | protein kinase, putative | 0.002 | 0.0276 | 0.2964 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.576 | 0.5717 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0018 | 0.0184 | 0.0163 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0025 | 0.0445 | 0.5831 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0025 | 0.0479 | 0.6422 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0016 | 0.0101 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0054 | 0.1627 | 0.1541 |
Leishmania major | protein kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1441 | 0.1422 |
Mycobacterium ulcerans | beta-lactamase | 0.0031 | 0.069 | 0.2655 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1441 | 0.1422 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0142 | 0.0073 |
Brugia malayi | bHLH-PAS transcription factor | 0.0049 | 0.1409 | 0.1638 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1441 | 0.1353 |
Schistosoma mansoni | gamma-glutamyltransferase-like protein 3 (T03 family) | 0.0217 | 0.8173 | 0.8154 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0626 | 0.0606 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0626 | 0.0531 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0018 | 0.0184 | 0.0124 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0626 | 0.0626 |
Brugia malayi | Importin beta-1 subunit | 0.0025 | 0.0445 | 0.0446 |
Schistosoma mansoni | hypothetical protein | 0.0263 | 1 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0025 | 0.0445 | 0.0347 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1441 | 0.1422 |
Echinococcus granulosus | lamin | 0.0029 | 0.0626 | 0.0606 |
Brugia malayi | PAS domain containing protein | 0.0066 | 0.2094 | 0.2485 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0178 | 0.6585 | 0.6585 |
Echinococcus granulosus | geminin | 0.0157 | 0.576 | 0.5751 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0016 | 0.0101 | 0.0101 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.1441 | 0.1678 |
Mycobacterium tuberculosis | Probable bifunctional acylase GgtA: cephalosporin acylase (GL-7ACA acylase) + gamma-glutamyltranspeptidase (GGT) | 0.0071 | 0.232 | 0.3067 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.1441 | 0.1441 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0191 | 0.7104 | 0.7074 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0016 | 0.0101 | 0.0022 |
Plasmodium vivax | SET domain protein, putative | 0.0025 | 0.0479 | 0.6422 |
Loa Loa (eye worm) | TAR-binding protein | 0.0054 | 0.1627 | 0.1627 |
Leishmania major | importin beta-1 subunit, putative | 0.002 | 0.0258 | 0.266 |
Schistosoma mansoni | tar DNA-binding protein | 0.0054 | 0.1627 | 0.1541 |
Onchocerca volvulus | 0.0049 | 0.1431 | 0.1237 | |
Echinococcus multilocularis | geminin | 0.0157 | 0.576 | 0.5751 |
Brugia malayi | TAR-binding protein | 0.0054 | 0.1627 | 0.1908 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0018 | 0.0184 | 0.0184 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0795 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.069 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0031 | 0.069 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.069 | 0.069 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0018 | 0.0184 | 0.2408 |
Mycobacterium leprae | conserved hypothetical protein | 0.0031 | 0.069 | 1 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0142 | 0.5152 | 0.5142 |
Mycobacterium leprae | Probable lipase LipE | 0.0031 | 0.069 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0031 | 0.069 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.4467 | 0.4467 |
Plasmodium falciparum | importin beta, putative | 0.0025 | 0.0445 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0031 | 0.069 | 0.069 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1441 | 0.1422 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0795 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0626 | 0.0626 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0017 | 0.0142 | 0.0698 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 22.02 % | Inhibition of endothelin A receptor in New Zealand white rabbit aortic rings assessed as inhibition of endothelin-1-induced vascular contraction at 10'-6 M | ChEMBL. | 21652209 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.