Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 2 of 9 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv0568 | OG5_135997 | Possible cytochrome P450 135B1 Cyp135B1 |
M. tuberculosis | Rv3685c | OG5_135997 | Probable cytochrome P450 137 Cyp137 |
M. tuberculosis | Rv0136 | OG5_135997 | Probable cytochrome P450 138 Cyp138 |
M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
M. tuberculosis | Rv0764c | OG5_129288 | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lano ... |
M. tuberculosis | Rv3117 | OG5_127129 | Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfa ... |
M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD |
M. tuberculosis | Rv2392 | OG5_129962 | Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, t ... |
M. tuberculosis | Rv2726c | OG5_130716 | Probable diaminopimelate epimerase DapF (DAP epimerase) |
M. tuberculosis | Rv0429c | OG5_128237 | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) |
M. tuberculosis | Rv0824c | OG5_137533 | Probable acyl-[acyl-carrier protein] desaturase DesA1 (acyl-[ACP] desaturase) (s ... |
M. tuberculosis | Rv1094 | OG5_237738 | Possible acyl-[acyl-carrier protein] desaturase DesA2 (acyl-[ACP] desaturase) (s ... |
M. tuberculosis | Rv3132c | OG5_153508 | Two component sensor histidine kinase DevS |
M. tuberculosis | Rv2763c | OG5_128410 | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) |
M. tuberculosis | Rv1547 | OG5_132143 | Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) |
M. tuberculosis | Rv2343c | OG5_132296 | Probable DNA primase DnaG |
M. tuberculosis | Rv0675 | OG5_133017 | Probable enoyl-CoA hydratase EchA5 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
M. tuberculosis | Rv1350 | OG5_126618 | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carri ... |
M. tuberculosis | Rv1715 | OG5_131710 | Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3 (beta-hydroxybutyryl-CoA dehyd ... |
M. tuberculosis | Rv2500c | OG5_128729 | Possible acyl-CoA dehydrogenase FadE19 (MMGC) |
M. tuberculosis | Rv0400c | OG5_129299 | Acyl-CoA dehydrogenase FadE7 |
M. tuberculosis | Rv3803c | OG5_237550 | Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG ... |
M. tuberculosis | Rv3607c | OG5_133572 | Probable dihydroneopterin aldolase FolB (DHNA) |
M. tuberculosis | Rv2447c | OG5_126889 | Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate syn ... |
M. tuberculosis | Rv0727c | OG5_127052 | Possible L-fuculose phosphate aldolase FucA (L-fuculose-1-phosphate aldolase) |