Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 7 of 9 (records 151-175) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv2773c | OG5_131385 | Dihydrodipicolinate reductase DapB (DHPR) |
| M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) |
| M. tuberculosis | Rv2783c | OG5_128725 | Bifunctional protein polyribonucleotide nucleotidyltransferase GpsI: guanosine p ... |
| M. tuberculosis | Rv2831 | OG5_142767 | Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv2855 | OG5_126785 | NADPH-dependent mycothiol reductase Mtr |
| M. tuberculosis | Rv2861c | OG5_126721 | Methionine aminopeptidase MapB (map) (peptidase M) |
| M. tuberculosis | Rv2870c | OG5_130462 | Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomera ... |
| M. tuberculosis | Rv2888c | OG5_141344 | Probable amidase AmiC (aminohydrolase) |
| M. tuberculosis | Rv2900c | OG5_144408 | Possible formate dehydrogenase H FdhF (formate-hydrogen-lyase-linked, selenocyst ... |
| M. tuberculosis | Rv2941 | OG5_127582 | Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... |
| M. tuberculosis | Rv2949c | OG5_159033 | Chorismate pyruvate lyase |
| M. tuberculosis | Rv2981c | OG5_130117 | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D- ... |
| M. tuberculosis | Rv2986c | OG5_130206 | DNA-binding protein HU homolog HupB (histone-like protein) (HLP) (21-kDa laminin ... |
| M. tuberculosis | Rv3010c | OG5_126758 | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) |
| M. tuberculosis | Rv3045 | OG5_126661 | Probable NADP-dependent alcohol dehydrogenase AdhC |
| M. tuberculosis | Rv3051c | OG5_126839 | Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductas ... |
| M. tuberculosis | Rv3068c | OG5_127226 | Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM) |
| M. tuberculosis | Rv3086 | OG5_127257 | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) |
| M. tuberculosis | Rv3106 | OG5_128406 | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) |
| M. tuberculosis | Rv3117 | OG5_127129 | Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfa ... |
| M. tuberculosis | Rv3133c | OG5_127928 | Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family ... |
| M. tuberculosis | Rv3214 | OG5_132095 | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-depende ... |
| M. tuberculosis | Rv3219 | OG5_237613 | Transcriptional regulatory protein WhiB-like WhiB1. Contains [4FE-4S]2+ cluster. |
| M. tuberculosis | Rv3247c | OG5_126920 | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) |
| M. tuberculosis | Rv3248c | OG5_127233 | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adoh ... |