Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 8 of 9 (records 176-200) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3266c | OG5_128895 | dTDP-6-deoxy-L-lyxo-4-hexulose reductase RmlD (dTDP-rhamnose modification protei ... |
| M. tuberculosis | Rv3273 | OG5_129533 | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehy ... |
| M. tuberculosis | Rv3279c | OG5_126858 | Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-Co ... |
| M. tuberculosis | Rv3290c | OG5_129508 | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysi ... |
| M. tuberculosis | Rv3307 | OG5_128114 | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) |
| M. tuberculosis | Rv3316 | OG5_144477 | Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (succinic dehyd ... |
| M. tuberculosis | Rv3317 | OG5_168828 | Probable succinate dehydrogenase (hydrophobic membrane anchor subunit) SdhD (suc ... |
| M. tuberculosis | Rv3319 | OG5_126893 | Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic d ... |
| M. tuberculosis | Rv3339c | OG5_127057 | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv3373 | OG5_239166 | Probable enoyl-CoA hydratase EchA18 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv3375 | OG5_174922 | Probable amidase AmiD (acylamidase) (acylase) |
| M. tuberculosis | Rv3409c | OG5_152459 | Cholesterol oxidase ChoD (cholesterol-O2 oxidoreductase) |
| M. tuberculosis | Rv3423c | OG5_131271 | Alanine racemase Alr |
| M. tuberculosis | Rv3457c | OG5_130460 | Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha cha ... |
| M. tuberculosis | Rv3465 | OG5_132926 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimer ... |
| M. tuberculosis | Rv3490 | OG5_129327 | Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosph ... |
| M. tuberculosis | Rv3506 | OG5_239145 | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligas ... |
| M. tuberculosis | Rv3515c | OG5_239171 | Fatty-acid-CoA ligase FadD19 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthas ... |
| M. tuberculosis | Rv3545c | OG5_132455 | Probable cytochrome P450 125 Cyp125 |
| M. tuberculosis | Rv3547 | OG5_184391 | Deazaflavin-dependent nitroreductase Ddn |
| M. tuberculosis | Rv3550 | No group | Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv3566c | OG5_131280 | Arylamine N-acetyltransferase Nat (arylamine acetylase) |
| M. tuberculosis | Rv3581c | OG5_130616 | Probable 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF (MECPS) |
| M. tuberculosis | Rv3588c | OG5_127503 | Beta-carbonic anhydrase CanB |
| M. tuberculosis | Rv3601c | OG5_134769 | Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase ... |