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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8299 records found | Showing page 2 of 332 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
T. brucei | Tb927.10.7570 | OG5_128029 | dihydrolipoamide acetyltransferase E2 subunit, putative | 1011 |
T. brucei | Tb927.3.2030 | OG5_127552 | acylphosphatase, putative | 1011 |
T. brucei | Tb927.3.1790 | OG5_127524 | pyruvate dehydrogenase E1 beta subunit, putative | 1011 |
T. brucei | Tb927.10.2350 | OG5_145729 | pyruvate dehydrogenase complex E3 binding protein, putative | 1011 |
T. brucei | Tb927.6.4210 | OG5_131364 | aldehyde dehydrogenase, putative | 1011 |
T. brucei | Tb427.10.4330 | No group | 2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor, putative | 1001 |
T. brucei | Tb927.7.3360 | OG5_127590 | farnesyl pyrophosphate synthase | 101 |
T. brucei | Tb927.11.13730 | OG5_126750 | ornithine decarboxylase | 101 |
T. brucei | Tb927.10.14070 | OG5_128252 | mevalonate diphosphate decarboxylase | 81 |
T. brucei | Tb927.4.4590 | OG5_157978 | AGC family serine/threonine kinase, putative | 81 |
T. brucei | Tb11.v5.0718 | OG5_126888 | protein kinase, putative | 81 |
T. brucei | Tb927.10.10390 | OG5_126785 | trypanothione reductase | 81 |
T. brucei | Tb927.6.4410 | OG5_128279 | S-adenosylmethionine decarboxylase | 81 |
T. brucei | Tb927.10.880 | OG5_129576 | thymidine kinase | 81 |
T. brucei | Tb927.4.3810 | OG5_126694 | DNA-directed RNA polymerase II subunit 2, putative | 81 |
T. brucei | Tb927.10.13560 | OG5_128252 | mevalonate-diphosphate decarboxylase | 81 |
T. brucei | Tb927.10.4990 | OG5_126712 | cdc2-related kinase 3 | 81 |
T. brucei | Tb927.11.9590 | OG5_127233 | S-adenosylhomocysteine hydrolase, putative | 81 |
T. brucei | Tb927.8.2000 | OG5_126792 | cyclophilin, putative | 81 |
T. brucei | Tb927.11.14780 | OG5_127555 | phosphomannose isomerase | 81 |
T. brucei | Tb927.10.1070 | OG5_126712 | cdc2-related kinase 1 | 81 |
T. brucei | Tb927.5.3830 | OG5_127289 | dihydroorotate dehydrogenase (fumarate) | 81 |
T. brucei | Tb927.7.4770 | OG5_127452 | cyclophilin-type peptidyl-prolyl cis-trans isomerase, putative | 81 |
T. brucei | Tb927.10.12370 | OG5_128698 | gamma-glutamylcysteine synthetase | 81 |
T. brucei | Tb927.10.13630 | OG5_126880 | glucosidase, putative | 81 |