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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8243 records found | Showing page 2 of 330 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.26.0140 | OG5_127379 | adenine phosphoribosyltransferase | 316 |
L. major | LmjF.05.0970 | OG5_127129 | 3-mercaptopyruvate sulfurtransferase | 316 |
L. major | LmjF.12.0530 | OG5_126980 | glucose-6-phosphate isomerase | 316 |
L. major | LmjF.35.0020 | OG5_126685 | pyruvate kinase | 316 |
L. major | LmjF.10.0465 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.10.0460 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.10.0480 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.10.0470 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.34.2000 | OG5_150045 | pyroglutamyl-peptidase I (C15 family) | 306 |
L. major | LmjF.04.0060 | OG5_145769 | DNA topoisomerase type IB small subunit | 306 |
L. major | LmjF.31.1220 | OG5_128905 | vacuolar-type proton translocating pyrophosphatase 1, putative | 306 |
L. major | LmjF.20.1310 | OG5_138266 | small myristoylated protein-1 | 306 |
L. major | LmjF.04.1160 | OG5_127400 | 301 | |
L. major | LmjF.30.3520 | OG5_126734 | S-adenosylmethionine synthetase | 301 |
L. major | LmjF.28.2860 | OG5_127410 | cytosolic malate dehydrogenase | 301 |
L. major | LmjF.34.1260 | OG5_127218 | mitochondrial DNA polymerase I protein A, putative | 301 |
L. major | LmjF.18.1080 | OG5_126748 | protein kinase A catalytic subunit | 301 |
L. major | LmjF.28.0690 | OG5_126821 | serine/threonine protein phosphatase catalytic subunit, putative | 301 |
L. major | LmjF.10.0890 | OG5_128118 | FKBP-type peptidyl-prolyl cis-trans isomerase, putative | 301 |
L. major | LmjF.08.1070 | OG5_126607 | cathepsin L-like protease | 301 |
L. major | LmjF.23.0950 | OG5_127293 | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 301 |
L. major | LmjF.33.1630 | OG5_126792 | cyclophilin 4, putative | 301 |
L. major | LmjF.07.1030 | OG5_128367 | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 301 |
L. major | LmjF.08.1050 | OG5_126607 | cathepsin L-like protease | 301 |
L. major | LmjF.19.1530 | OG5_126727 | peptidylprolyl isomerase-like protein | 301 |