Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8361 records found | Showing page 1 of 335 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
T. brucei | Tb927.7.3360 | OG5_127590 | farnesyl pyrophosphate synthase | 405 |
T. brucei | Tb927.1.700 | OG5_126776 | phosphoglycerate kinase | 370 |
T. brucei | Tb927.10.2890 | OG5_126698 | enolase | 370 |
T. brucei | Tb11.v5.0531 | OG5_127143 | fructose-bisphosphate aldolase, glycosomal, putative | 370 |
T. brucei | Tb927.11.2730 | OG5_126853 | UDP-galactose 4-epimerase | 365 |
T. brucei | Tb927.6.2030 | OG5_140087 | STE/STE11 serine/threonine-protein kinase, putative | 365 |
T. brucei | Tb927.11.4700 | OG5_126583 | prostaglandin f synthase | 355 |
T. brucei | Tb927.6.560 | OG5_127800 | cysteine peptidase C (CPC) | 355 |
T. brucei | Tb927.10.14240 | OG5_127597 | N-myristoyltransferase | 355 |
T. brucei | Tb927.9.5590 | OG5_128755 | DNA topoisomerase ii | 345 |
T. brucei | Tb927.3.1380 | OG5_127099 | ATP synthase subunit beta, mitochondrial | 340 |
T. brucei | Tb927.8.5950 | OG5_144825 | mitogen-activated protein kinase kinase 4, putative | 340 |
T. brucei | Tb11.v5.0718 | OG5_126888 | protein kinase, putative | 340 |
T. brucei | Tb927.10.4990 | OG5_126712 | cdc2-related kinase 3 | 340 |
T. brucei | Tb927.4.1080 | OG5_127237 | V-type ATPase, A subunit, putative | 340 |
T. brucei | Tb927.7.6220 | OG5_131734 | calcium/calmodulin-dependent protein kinase, putative | 340 |
T. brucei | Tb927.11.3140 | OG5_127439 | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 340 |
T. brucei | Tb927.10.1070 | OG5_126712 | cdc2-related kinase 1 | 340 |
T. brucei | Tb927.8.2210 | OG5_133937 | pteridine reductase 1 | 340 |
T. brucei | Tb927.11.150 | OG5_126617 | receptor-type adenylate cyclase GRESAG 4, putative | 340 |
T. brucei | Tb11.v5.0671 | OG5_126748 | protein kinase A catalytic subunit, putative | 340 |
T. brucei | Tb927.9.12110 | OG5_127175 | 6-phosphogluconate dehydrogenase, decarboxylating | 335 |
T. brucei | Tb927.6.4280 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 335 |
T. brucei | Tb927.6.4300 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 335 |
T. brucei | Tb927.6.4590 | OG5_128638 | glutamyl-tRNA synthetase, putative | 330 |