Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | fatty acid desaturase, putative | 0.3079 | 1 | 1 |
Leishmania major | fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0348 | 0.0615 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Leishmania major | delta-6 fatty acid desaturase | 0.0348 | 0.0615 | 0.0615 |
Toxoplasma gondii | sphingolipid delta 4 desaturase/c-4 hydroxylase protein des2 family protein | 0.0348 | 0.0615 | 0.5 |
Onchocerca volvulus | 0.3079 | 1 | 1 | |
Leishmania major | fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Trypanosoma brucei | sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Loa Loa (eye worm) | fatty acid desaturase | 0.0348 | 0.0615 | 0.0699 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0348 | 0.0615 | 1 |
Trypanosoma brucei | delta-4 fatty acid desaturase | 0.0348 | 0.0615 | 0.0615 |
Leishmania major | fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Leishmania major | fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Leishmania major | fatty-acid desaturase, putative | 0.3079 | 1 | 1 |
Leishmania major | delta-4 fatty acid desaturase | 0.0348 | 0.0615 | 0.0615 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.2731 | 0.8804 | 1 |
Trypanosoma cruzi | cytochrome b5-dependent oleate desaturase | 0.0348 | 0.0615 | 0.0615 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3_2 | 0.0348 | 0.0615 | 1 |
Leishmania major | fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Echinococcus granulosus | Fatty acid desaturase type 1 | 0.0348 | 0.0615 | 0.5 |
Leishmania major | delta-5 fatty acid desaturase | 0.0348 | 0.0615 | 0.0615 |
Brugia malayi | acyl-CoA desaturase | 0.2731 | 0.8804 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.0615 | 0.0699 |
Brugia malayi | Cytochrome P450 family protein | 0.0377 | 0.0714 | 0.0811 |
Brugia malayi | Fatty acid desaturase family protein | 0.0348 | 0.0615 | 0.0699 |
Loa Loa (eye worm) | fatty acid desaturase | 0.0348 | 0.0615 | 0.0699 |
Leishmania major | delta-12 fatty acid desaturase | 0.0348 | 0.0615 | 0.0615 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0348 | 0.0615 | 0.5 |
Mycobacterium tuberculosis | Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (f | 0.0348 | 0.0615 | 0.5 |
Onchocerca volvulus | 0.3079 | 1 | 1 | |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.2731 | 0.8804 | 0.8804 |
Trypanosoma cruzi | delta-4 fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.3079 | 1 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.2731 | 0.8804 | 0.8804 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0348 | 0.0615 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0377 | 0.0714 | 0.0811 |
Schistosoma mansoni | fatty acid desaturase | 0.0348 | 0.0615 | 0.5 |
Brugia malayi | Delta5 fatty acid desaturase | 0.0348 | 0.0615 | 0.0699 |
Trypanosoma cruzi | delta-4 fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Echinococcus multilocularis | Fatty acid desaturase, type 1 | 0.0348 | 0.0615 | 0.5 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0348 | 0.0615 | 0.5 |
Trypanosoma brucei | cytochrome b5-dependent oleate desaturase | 0.0348 | 0.0615 | 0.0615 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.2731 | 0.8804 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0348 | 0.0615 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0348 | 0.0615 | 1 |
Mycobacterium tuberculosis | Probable conserved membrane protein | 0.0348 | 0.0615 | 0.5 |
Trypanosoma cruzi | sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Trypanosoma brucei | delta-6 fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.2731 | 0.8804 | 0.5 |
Mycobacterium ulcerans | transmembrane alkane 1-monooxygenase AlkB | 0.0348 | 0.0615 | 1 |
Echinococcus granulosus | Sphingolipid delta4 desaturase DES1 | 0.0348 | 0.0615 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0348 | 0.0615 | 1 |
Leishmania major | fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative | 0.0348 | 0.0615 | 0.0615 |
Loa Loa (eye worm) | FAT-3 protein | 0.0348 | 0.0615 | 0.0699 |
Brugia malayi | Fatty acid desaturase family protein | 0.0348 | 0.0615 | 0.0699 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.