TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 379.431 | Formula: C17H21N3O5S
H donors: 2 H acceptors: 5 LogP: 0.76 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: S[C@H](C(=O)N[C@H]1CCC(=O)N(N(C1=O)CC(=O)O)C)Cc1ccccc1
InChi: 1S/C17H21N3O5S/c1-19-14(21)8-7-12(17(25)20(19)10-15(22)23)18-16(24)13(26)9-11-5-3-2-4-6-11/h2-6,12-13,26H,7-10H2,1H3,(H,18,24)(H,22,23)/t12-,13-/m0/s1
InChiKey: DLMMMBXYCBMUDE-STQMWFEESA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	angiotensin I converting enzyme	Starlite/ChEMBL	No references
Homo sapiens	membrane metallo-endopeptidase	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Onchocerca volvulus		Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Neospora caninum	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	Get druggable targets OG5_127344	All targets in OG5_127344
Schistosoma japonicum	IPR000718,Peptidase M13, neprilysin,domain-containing	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Schistosoma japonicum	ko:K01415 endothelin-converting enzyme [EC3.4.24.71], putative	Get druggable targets OG5_127344	All targets in OG5_127344
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	Get druggable targets OG5_127344	All targets in OG5_127344
Toxoplasma gondii	peptidase family M13 protein	Get druggable targets OG5_127344	All targets in OG5_127344
Brugia malayi	Peptidase family M13 containing protein	Get druggable targets OG5_127344	All targets in OG5_127344
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	peptidase family M13 containing protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	peptidase family M13 containing protein	Get druggable targets OG5_127344	All targets in OG5_127344
Brugia malayi	Angiotensin-converting enzyme family protein	Get druggable targets OG5_131988	All targets in OG5_131988
Loa Loa (eye worm)	angiotensin-converting enzyme family protein	Get druggable targets OG5_131988	All targets in OG5_131988
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Mycobacterium leprae	probable zinc metalloprotease	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Echinococcus granulosus	endothelin converting enzyme 1	Get druggable targets OG5_127344	All targets in OG5_127344
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127344	All targets in OG5_127344
Echinococcus multilocularis	endothelin converting enzyme 1	Get druggable targets OG5_127344	All targets in OG5_127344
Mycobacterium ulcerans	zinc metalloprotease	Get druggable targets OG5_127344	All targets in OG5_127344

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	hypothetical protein, conserved	0.01	0.0971	0.2903
Trypanosoma brucei	metacaspase MCA3	0.0053	0.0317	0.0763
Trypanosoma brucei	metacaspase	0.0053	0.0317	0.0763
Trypanosoma brucei	metacaspase 5, putative	0.0053	0.0317	0.0763
Trichomonas vaginalis	glutaminase, putative	0.0271	0.336	1
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0058	0.0386	0.0845
Echinococcus multilocularis	Alpha N acetylgalactosaminidase	0.0122	0.1278	0.2661
Loa Loa (eye worm)	angiotensin-converting enzyme family protein	0.0749	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713
Echinococcus multilocularis	geminin	0.0358	0.4572	1
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0122	0.1278	0.2795
Echinococcus multilocularis	snurportin 1	0.0306	0.3836	0.8361
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0081	0.0714	0.1562
Loa Loa (eye worm)	ubiquitin conjugating enzyme protein 13	0.0256	0.3143	0.3086
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0053	0.0317	0.0763
Trichomonas vaginalis	set domain proteins, putative	0.0235	0.2857	0.8463
Loa Loa (eye worm)	jmjC domain-containing protein	0.007	0.0557	0.0478
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0114	0.1172	0.1098
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Brugia malayi	jmjC domain containing protein	0.007	0.0557	0.0478
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0053	0.0317	0.0763
Brugia malayi	Ubiquitin conjugating enzyme protein 13	0.0256	0.3143	0.3086
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0084	0.0758	0.0681
Trypanosoma cruzi	metacaspase 5, putative	0.0053	0.0317	0.0763
Loa Loa (eye worm)	hypothetical protein	0.0114	0.1172	0.1098
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0714	0.0636
Trichomonas vaginalis	ubiquitin-conjugating enzyme E2, putative	0.0256	0.3143	0.9337
Echinococcus multilocularis	caspase 8	0.0053	0.0317	0.052
Echinococcus granulosus	caspase 2	0.0101	0.0997	0.2036
Trichomonas vaginalis	alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative	0.0081	0.0714	0.1926
Brugia malayi	jmjC domain containing protein	0.007	0.0557	0.0478
Toxoplasma gondii	ubiquitin-conjugating enzyme subfamily protein	0.0256	0.3143	1
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713
Schistosoma mansoni	caspase-7 (C14 family)	0.0139	0.1518	0.332
Schistosoma mansoni	hypothetical protein	0.0306	0.3836	0.8391
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0098	0.0952	0.2082
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0207	0.246	0.2396
Plasmodium vivax	hypothetical protein, conserved	0.0053	0.0317	0.0763
Loa Loa (eye worm)	ubiquitin conjugating enzyme protein 13	0.0256	0.3143	0.3086
Trypanosoma cruzi	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Brugia malayi	hypothetical protein	0.0049	0.0267	0.0185
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Echinococcus granulosus	ubiquitin conjugating enzyme E2 N	0.0256	0.3143	0.6817
Echinococcus multilocularis	lysine specific demethylase 5A	0.007	0.0557	0.1057
Leishmania major	ubiquitin-conjugating enzyme e2, putative	0.0256	0.3143	1
Trypanosoma cruzi	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Schistosoma mansoni	caspase-7 (C14 family)	0.0101	0.0997	0.2181
Echinococcus multilocularis	caspase	0.0139	0.1518	0.3196
Leishmania major	metacaspase, putative	0.0053	0.0317	0.0763
Brugia malayi	Cell death protein 3 precursor	0.0101	0.0997	0.0922
Trypanosoma cruzi	ubiquitin-conjugating enzyme E2, putative	0.0256	0.3143	1
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0053	0.0317	0.0763
Brugia malayi	mucosa associated lymphoid tissue lymphoma translocation protein 1	0.0053	0.0317	0.0236
Plasmodium vivax	ubiquitin-conjugating enzyme E2 N, putative	0.0256	0.3143	1
Mycobacterium leprae	probable zinc metalloprotease	0.0114	0.1172	1
Loa Loa (eye worm)	hypothetical protein	0.0101	0.0997	0.0922
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0122	0.1278	0.2795
Trypanosoma cruzi	metacaspase, putative	0.0053	0.0317	0.0763
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Toxoplasma gondii	peptidase family M13 protein	0.0114	0.1172	0.3559
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0098	0.0952	0.0876
Echinococcus granulosus	snurportin 1	0.0306	0.3836	0.8361
Entamoeba histolytica	ubiquitin-conjugating enzyme family protein	0.0256	0.3143	0.5
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0758	0.0681
Echinococcus multilocularis	caspase 3, apoptosis cysteine peptidase	0.0139	0.1518	0.3196
Trypanosoma cruzi	ubiquitin-conjugating enzyme E2, putative	0.0256	0.3143	1
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0083	0.0182
Trypanosoma cruzi	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Echinococcus granulosus	caspase	0.0139	0.1518	0.3196
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0317	0.0236
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0058	0.0386	0.0845
Echinococcus multilocularis	caspase 2	0.0101	0.0997	0.2036
Trypanosoma cruzi	metacaspase, putative	0.0053	0.0317	0.0763
Brugia malayi	Pre-SET motif family protein	0.0207	0.246	0.2396
Brugia malayi	RNA, U transporter 1	0.0081	0.0718	0.064
Schistosoma mansoni	ubiquitin conjugating enzyme 13	0.0256	0.3143	0.6875
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0098	0.0952	0.1935
Trypanosoma brucei	Metacaspase-4	0.0053	0.0317	0.0763
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0372	0.0291
Toxoplasma gondii	melibiase subfamily protein	0.0122	0.1278	0.3904
Mycobacterium ulcerans	glutaminase	0.0271	0.336	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.023	0.2784	0.2723
Trypanosoma cruzi	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Onchocerca volvulus	Cell death protein 3 homolog	0.0101	0.0997	0.3296
Trypanosoma brucei	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Trypanosoma brucei	hypothetical protein, conserved	0.01	0.0971	0.2903
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0758	0.0681
Trypanosoma cruzi	Enriched in surface-labeled proteome protein 12	0.01	0.0971	0.2903
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0228	0.2762	1
Schistosoma mansoni	jumonji domain containing protein	0.007	0.0557	0.1219
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0122	0.1278	0.2795
Trichomonas vaginalis	ubiquitin-conjugating enzyme E2, putative	0.0256	0.3143	0.9337
Trypanosoma cruzi	metacaspase 5, putative	0.0053	0.0317	0.0763
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0098	0.0952	0.0876
Schistosoma mansoni	hypothetical protein	0.0358	0.4572	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0098	0.0952	0.1935
Schistosoma mansoni	caspase-3 (C14 family)	0.0139	0.1518	0.332
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0306	0.3836	0.3785
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0098	0.0952	0.1935
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0058	0.0386	0.0845
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0058	0.0386	0.0845
Echinococcus multilocularis	Glycoside hydrolase, family 27	0.0122	0.1278	0.2661
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0098	0.0952	0.2082
Trypanosoma cruzi	metacaspase, putative	0.0053	0.0317	0.0763
Brugia malayi	glutaminase DH11.1	0.0271	0.336	0.3305
Echinococcus granulosus	lysine specific demethylase 5A	0.007	0.0557	0.1057
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713
Brugia malayi	ubiquitin conjugating enzyme protein 13	0.0256	0.3143	0.3086
Schistosoma mansoni	jumonji/arid domain-containing protein	0.007	0.0557	0.1219
Loa Loa (eye worm)	hypothetical protein	0.0114	0.1172	0.1098
Loa Loa (eye worm)	hypothetical protein	0.0114	0.1172	0.1098
Loa Loa (eye worm)	glutaminase 2	0.0271	0.336	0.3305
Echinococcus granulosus	caspase 8	0.0053	0.0317	0.052
Echinococcus granulosus	Alpha N acetylgalactosaminidase	0.0122	0.1278	0.2661
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0758	0.0681
Plasmodium vivax	metacaspase 1, putative	0.0053	0.0317	0.0763
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0058	0.0386	0.0845
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.007	0.0557	0.1057
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0081	0.0714	0.1562
Trypanosoma brucei	metacaspase MCA2	0.0053	0.0317	0.0763
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0083	0.0182
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0098	0.0952	0.2082
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0267	0.0185
Mycobacterium ulcerans	zinc metalloprotease	0.0114	0.1172	0.3323
Trypanosoma cruzi	metacaspase, putative	0.0053	0.0317	0.0763
Brugia malayi	Melibiase family protein	0.0081	0.0714	0.0636
Echinococcus granulosus	caspase 3	0.0086	0.0787	0.1569
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Onchocerca volvulus		0.0049	0.0267	0.0661
Plasmodium falciparum	ubiquitin-conjugating enzyme E2 N, putative	0.0256	0.3143	1
Schistosoma mansoni	hypothetical protein	0.0358	0.4572	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0098	0.0952	0.1935
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.007	0.0557	0.1057
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Brugia malayi	follicle stimulating hormone receptor	0.023	0.2784	0.2723
Schistosoma mansoni	alpha-galactosidase/alpha-n-acetylgalactosaminidase	0.0122	0.1278	0.2795
Echinococcus granulosus	geminin	0.0358	0.4572	1
Onchocerca volvulus		0.0235	0.2857	1
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0114	0.1172	0.2564
Schistosoma mansoni	glutaminase	0.0271	0.336	0.735
Echinococcus multilocularis	caspase 3	0.0086	0.0787	0.1569
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Schistosoma mansoni	jumonji/arid domain-containing protein	0.007	0.0557	0.1219
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Echinococcus multilocularis	apoptotic protease activating factor 1	0.0049	0.0267	0.0409
Onchocerca volvulus		0.0056	0.0372	0.1041
Echinococcus multilocularis	endothelin converting enzyme 1	0.0114	0.1172	0.2426
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0758	0.0681
Echinococcus granulosus	endothelin converting enzyme 1	0.0114	0.1172	0.2426
Loa Loa (eye worm)	glutaminase	0.0271	0.336	0.3305
Echinococcus multilocularis	ubiquitin conjugating enzyme E2 N	0.0256	0.3143	0.6817
Echinococcus granulosus	caspase 3 apoptosis cysteine peptidase	0.0139	0.1518	0.3196
Brugia malayi	Peptidase family M13 containing protein	0.0114	0.1172	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713
Schistosoma mansoni	subfamily C14A unassigned peptidase (C14 family)	0.0053	0.0317	0.0693
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0053	0.0317	0.0713
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0084	0.0758	0.0681
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0786	0.0709
Trypanosoma brucei	ubiquitin-protein ligase, putative	0.0256	0.3143	1
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0114	0.1172	0.4065
Schistosoma mansoni	hypothetical protein	0.0049	0.0267	0.0583
Echinococcus granulosus	apoptotic protease activating factor 1	0.0049	0.0267	0.0409
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.0317	0.0713

Activities

Activity type	Activity value	Assay description	Source	Reference
ED50 (functional)	= 0.13 uM kg-1	In vivo effective dose against angiotensin I induced pressor response after intravenous administration in normotensive rats	ChEMBL.	No reference
I50 (binding)	= 16 nM	In vitro inhibitory activity of the compound against angiotensin converting enzyme (ACE) in rat was determined	ChEMBL.	No reference
I50 (binding)	= 55 nM	In vitro inhibitory activity of the compound against neutral endopeptidase (NEP) was determined	ChEMBL.	No reference
IC50 (binding)	= 16 nM	In vitro inhibitory activity of the compound against angiotensin converting enzyme (ACE) in rat was determined	ChEMBL.	No reference
IC50 (binding)	= 55 nM	In vitro inhibitory activity of the compound against neutral endopeptidase (NEP) was determined	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL304881

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 104967