TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 499.075 | Formula: C24H31ClN8S
H donors: 3 H acceptors: 4 LogP: 4.81 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: N[C@@H]1CC[C@H](CC1)Nc1nc(NCc2csc(n2)c2ccccc2)c2c(n1)n(cn2)C(C)C.Cl
InChi: 1S/C24H30N8S.ClH/c1-15(2)32-14-27-20-21(26-12-19-13-33-23(28-19)16-6-4-3-5-7-16)30-24(31-22(20)32)29-18-10-8-17(25)9-11-18;/h3-7,13-15,17-18H,8-12,25H2,1-2H3,(H2,26,29,30,31);1H/t17-,18-;
InChiKey: UOBJMFWSKCGAJJ-YHSIFKNPSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	cyclin E2	Starlite/ChEMBL	References
Homo sapiens	cyclin A1	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Brugia malayi	Cyclin, N-terminal domain containing protein	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania infantum	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Echinococcus granulosus	cyclin B	Get druggable targets OG5_126649	All targets in OG5_126649
Candida albicans	likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania donovani	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania braziliensis	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Brugia malayi	Cyclin, N-terminal domain containing protein	Get druggable targets OG5_126649	All targets in OG5_126649
Echinococcus multilocularis	cyclin B	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclin A, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126649	All targets in OG5_126649
Candida albicans	likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction	Get druggable targets OG5_126649	All targets in OG5_126649
Schistosoma japonicum	ko:K05868 cyclin B, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Giardia lamblia	G2/mitotic-specific cyclin B	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma congolense	Cyclin, N-terminal domain/Cyclin, C-terminal domain containing protein, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Schistosoma mansoni	cyclin B	Get druggable targets OG5_126649	All targets in OG5_126649
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126649	All targets in OG5_126649
Candida albicans	hypothetical protein	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma cruzi	cyclin 6, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania mexicana	CYC2-like cyclin, putative,cyclin 6, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclins, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclins, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania infantum	CYC2-like cyclin, putative,cyclin 6, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania mexicana	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclin B, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma brucei	mitotic cyclin 6	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclin B, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclin B, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Onchocerca volvulus		Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclins, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania donovani	CYC2-like cyclin, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania braziliensis	CYC2-like cyclin, putative,cyclin 6, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma congolense	mitotic cyclin 6	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclins, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclin B, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma cruzi	cyclin, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Cryptosporidium hominis	mitotic cyclin-CYC2	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma brucei gambiense	cyclin 6,mitotic cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania major	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma cruzi	CYC2-like cyclin, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126649	All targets in OG5_126649
Entamoeba histolytica	cyclin, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Leishmania major	CYC2-like cyclin, putative,cyclin 6, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Candida albicans	likely B-type cyclin similar to S. cerevisiae CLB4 (YLR210W) and CLB3 (YDL155W) involved in G1/S transition	Get druggable targets OG5_126649	All targets in OG5_126649
Cryptosporidium parvum	cyclin	Get druggable targets OG5_126649	All targets in OG5_126649
Trichomonas vaginalis	cyclins, putative	Get druggable targets OG5_126649	All targets in OG5_126649
Trypanosoma cruzi	cyclin, putative	Get druggable targets OG5_126649	All targets in OG5_126649

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0303	0.0757	0.4749
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0279	0.0671	0.8431
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0292	0.0719	0.45
Echinococcus multilocularis	phosphatidylinositol 4,5 bisphosphate 3 kinase	0.0734	0.2288	0.2221
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0338	0.0881	0.2507
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0279	0.0671	0.4187
Brugia malayi	phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative	0.0203	0.0404	0.2147
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0303	0.0757	0.4749
Entamoeba histolytica	protein kinase rad3, putative	0.0165	0.0267	0.0908
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0303	0.0757	0.4749
Trichomonas vaginalis	conserved hypothetical protein	0.0114	0.0086	0.0387
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.2908	1	1
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0291	0.0716	0.8994
Loa Loa (eye worm)	hypothetical protein	0.0165	0.0267	0.0939
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0165	0.0267	0.1226
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0279	0.0671	0.4187
Loa Loa (eye worm)	cytochrome P450 family protein	0.013	0.0143	0.0296
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0128	0.0138	0.0724
Entamoeba histolytica	hypothetical protein	0.0455	0.1298	0.8126
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0303	0.0758	0.9519
Trypanosoma cruzi	target of rapamycin kinase 3	0.0303	0.0758	0.2116
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.0314	0.0796	0.4608
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0314	0.0796	0.4797
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0178	0.0312	0.1858
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0182	0.0329	0.4128
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0128	0.0138	0.0159
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0314	0.0796	0.4999
Giardia lamblia	Phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.034	0.0888	1
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0182	0.0329	0.0762
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0204	0.0405	0.2462
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0314	0.0796	0.0716
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0087	0.0008
Trichomonas vaginalis	PIKK family atypical protein kinase	0.02	0.0392	0.2377
Echinococcus granulosus	serine protein kinase ATM	0.0182	0.0329	0.0245
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0204	0.0405	0.1874
Brugia malayi	Cytochrome P450 family protein	0.013	0.0143	0.0387
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.0338	0.0881	0.3613
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0244	0.0548	0.2873
Echinococcus granulosus	phosphatidylinositol 4 kinase alpha	0.0128	0.0138	0.0052
Entamoeba histolytica	phosphatidylinositol 3-kinase 1, putative	0.0463	0.1325	0.8312
Echinococcus granulosus	phosphatidylinositol 4 phosphate 3 kinase C2	0.0319	0.0816	0.0736
Echinococcus multilocularis	serine protein kinase ATM	0.0182	0.0329	0.0245
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0206	0.0413	0.2515
Toxoplasma gondii	FATC domain-containing protein	0.0182	0.0329	0.3129
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0314	0.0796	0.2237
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0187	0.0344	0.2065
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0314	0.0796	0.4999
Loa Loa (eye worm)	hypothetical protein	0.0319	0.0816	0.3774
Brugia malayi	phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	0.0128	0.0138	0.035
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0734	0.2288	1
Echinococcus granulosus	phosphatidylinositol 3 kinase catalytic subunit	0.0128	0.0138	0.0052
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0289	0.0709	0.4436
Trichomonas vaginalis	PIKK family atypical protein kinase	0.029	0.0709	0.4437
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0314	0.0796	0.2237
Trypanosoma cruzi	phosphatidylinositol 3-kinase vps34-like	0.0204	0.0405	0.1004
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0128	0.0138	0.0159
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0338	0.0881	0.2507
Toxoplasma gondii	target of rapamycin (TOR), putative	0.03	0.0748	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0279	0.0671	0.4187
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0455	0.1298	0.8126
Echinococcus granulosus	phosphatidylinositol 45 bisphosphate 3 kinase	0.0734	0.2288	0.2221
Trichomonas vaginalis	phosphatidylinositol 4-kinase, putative	0.0128	0.0138	0.0724
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0128	0.0138	0.0724
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0182	0.0329	0.1103
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0165	0.0267	0.1566
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0303	0.0757	0.4749
Echinococcus multilocularis	phosphatidylinositol 4 kinase alpha	0.0128	0.0138	0.0052
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0338	0.0881	0.5374
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0289	0.0709	0.4436
Loa Loa (eye worm)	phosphatidylinositol 3	0.0659	0.202	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0136	0.0164	0.0405
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Trypanosoma cruzi	hypothetical protein, conserved	0.1007	0.3254	1
Echinococcus multilocularis	Zinc finger, PHD finger	0.0128	0.0138	0.0052
Loa Loa (eye worm)	phosphatidylinositol 3	0.0291	0.0716	0.3258
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.0314	0.0796	0.4608
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Entamoeba histolytica	Phosphatidylinositol 3- and 4-kinase family	0.0178	0.0312	0.1222
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0314	0.0796	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.029	0.0709	0.4437
Entamoeba histolytica	hypothetical protein	0.0182	0.0329	0.1336
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.0193	0.0365	0.4591
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.0531	0.1566	0.4669
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Plasmodium vivax	phosphatidylinositol 3-kinase, putative	0.0128	0.0138	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0187	0.0344	0.2065
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0204	0.0405	0.1451
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Trichomonas vaginalis	PIKK family atypical protein kinase	0.029	0.0709	0.4437
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0303	0.0757	0.4749
Echinococcus multilocularis	serine:threonine protein kinase SMG1	0.0165	0.0267	0.0183
Leishmania major	hypothetical protein, conserved	0.1075	0.3496	1
Trypanosoma brucei	phosphatidylinositol 4-kinase alpha, putative	0.0128	0.0138	0.1729
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0279	0.0671	0.4187
Trichomonas vaginalis	PIKK family atypical protein kinase	0.03	0.0748	0.4686
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0432	0.1792
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0292	0.0719	0.45
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0187	0.0344	0.2065
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0314	0.0796	0.0716
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.0338	0.0881	0.0802
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0314	0.0796	0.196
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0531	0.1566	1
Echinococcus granulosus	serine:threonine protein kinase SMG1	0.0165	0.0267	0.0183
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0182	0.0329	0.164
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0165	0.0267	0.0568
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0279	0.0671	0.1588
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0327	0.1247
Loa Loa (eye worm)	phosphatidylinositol 4-kinase type 3 alpha isoform 1	0.0128	0.0138	0.0268
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0319	0.0816	0.4931
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0204	0.0405	0.5093
Echinococcus multilocularis	phosphatidylinositol 4 phosphate 3 kinase C2	0.0319	0.0816	0.0736
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0314	0.0796	0.4999
Loa Loa (eye worm)	phosphatidylinositol 3	0.0314	0.0796	0.3672
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0204	0.0405	0.2462
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0415	0.1156	0.7335
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0204	0.0405	0.1874
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0182	0.0329	0.1964
Trichomonas vaginalis	PIKK family atypical protein kinase	0.029	0.0709	0.4437
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0531	0.1566	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0291	0.0716	0.4479
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0204	0.0405	0.2462
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.0531	0.1566	0.4669
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0531	0.1566	1
Schistosoma mansoni	fkbp-rapamycin associated protein	0.0165	0.0267	0.0824
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0136	0.0164	0.0242
Toxoplasma gondii	non-specific serine/threonine protein kinase	0.0182	0.0327	0.3103
Trichomonas vaginalis	conserved hypothetical protein	0.0182	0.0327	0.1953
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0289	0.0709	0.4436
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0189	0.0354	0.2128
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0415	0.1156	0.7335
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit gamma, putative	0.0531	0.1566	1
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.0291	0.0716	0.1722
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0314	0.0796	1
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0314	0.0796	0.196
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0314	0.0796	0.3225
Giardia lamblia	GTOR	0.0314	0.0796	0.8679
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0531	0.1566	1
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0128	0.0138	0.0236
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0303	0.0758	0.1846
Plasmodium falciparum	phosphatidylinositol 3-kinase	0.0128	0.0138	0.5
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0204	0.0405	0.2159
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.0338	0.0881	0.0802
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0128	0.0138	0.0236

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.4 microM	Inhibition of Cdk2/cyclinE	ChEMBL.	19854650
IC50 (binding)	= 0.7 microM	Inhibition of recombinant Cdk2/cyclinA	ChEMBL.	19854650

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL566539

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1063251